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In this study, researchers developed a carboxylated β-cyclodextrin formulation to enhance finasteride's physicochemical properties, achieving an encapsulation efficiency of about 85% and indicating potential for controlled drug release in therapeutic applications. Their findings suggest this inclusion complex could improve delivery of hydrophobic drugs like finasteride.

This study found that human meibomian glands differ significantly from free and hair-associated sebaceous glands in morphology and lipid composition, making them highly specialized holocrine glands.

This study examined argan oil inclusion complexes with β-CD, finding that these complexes improve the antibacterial efficacy, uniformity, and mechanical performance of hair treatment formulations while enhancing the durability of bleached hair, suggesting their potential as stable and effective cosmetic ingredients.

This study describes a new method using high-resolution mass spectrometry for analyzing multiple steroids in human scalp hair, with newborn hair showing the highest steroid concentrations among examined age groups.

In this study, the researchers developed and optimized a bilayer tablet containing Tamsulosin and Finasteride, achieving sustained and immediate drug release with favorable release kinetics, including first-order and anomalous diffusion mechanisms, through in vitro testing.

In this study, forming inclusion complexes of Finasteride and poly (ethylene glycol) resulted in significantly improved solubility and dissolution rates, suggesting a promising new solid form for enhanced drug release.

In this study, the researchers developed and optimized a curcumin nanocrystal gel to enhance skin permeability, reporting improved dissolution properties and antiproliferative effects on cell lines, suggesting it as a promising topical delivery system.

This review systematically summarizes the ethnopharmacology, phytochemistry, and pharmacological activities of Caryota mitis, highlighting its rich phytochemical profile and potential uses in treating various ailments, though many traditional uses still require further scientific validation.

This study found that betasitosterol-loaded nanostructured lipid carriers, when added to butter, improved its nutritional profile and antioxidant properties, maintaining stability over a three-month storage period.

This study found distinct hair metal profiles in Parkinson's disease patients, with lower iron and copper, higher manganese and arsenic, and explored their link to gut dysfunction and microbiota dysbiosis, suggesting hair metal analysis as a promising diagnostic tool.

This study demonstrates that MPM-FLIM multimodal imaging can effectively assess the delivery and dissolution of zinc pyrithione particles in human skin follicles using different application techniques.

This study demonstrates that bioequivalence for proposed 50-mg ritlecitinib capsules versus clinical 100-mg capsules can be supported using a PBPK model-based biowaiver, achieving over 90% probability of success.

This study introduces three spectrophotometric techniques for accurately determining finasteride and tadalafil in their combined pharmaceutical form, demonstrating their sustainability, sensitivity, and suitability for quality assurance, alongside a dissolution study following FDA guidelines.

This study found that the MXD/HP-β-CD GEL formulation promoted greater hair growth and improved gene expression related to hair growth in male rats compared to MXD solution or control groups.

This study found that forming solid dispersions and inclusion complexes of finasteride significantly increased its solubility compared to its pure form.

This study found that using nanoporous silica entrapped lipid-drug complexes enhanced the solubility and bioavailability of dutasteride in beagle dogs.

This review discusses newer therapeutic techniques for treating postacne scarring, highlighting their effectiveness for particular grades of scars, and reports no new clinical results.

This study found that the solid self-nanoemulsifying drug delivery system improved the oral bioavailability of carvedilol significantly compared to the drug alone, enhancing its solubility, dissolution, AUC, and Cmax.

This study reported that phytosome formulations of citrus flavonoids naringenin and naringin showed significantly increased oral bioavailability and plasma drug concentration in rabbits, suggesting that phytosome technology effectively addresses the pharmacokinetic limitations of these compounds.

This study developed and tested Bicalutamide-loaded lipid vesicles in dissolving microarray patches for topical application, finding that they effectively deliver Bicalutamide through murine skin while maintaining a favorable safety profile, suggesting potential to improve treatments for androgenetic alopecia.

In this study, the authors developed a medicated face mask using electrospun fibers to deliver the active compound Eflornithine hydrochloride for managing hirsutism. The mask showed promising drug release characteristics, a high safety profile, and reduced hair growth in mice.

In this study, researchers developed a coamorphous form of tadalafil and finasteride, showing improved solubility and dissolution in vitro, with results successfully translated in vivo in rats. They reported reasonable stability, suggesting this form could serve as a therapeutic alternative to the current marketed combination.

This study found that the n-hexane fraction from Leea indica leaves significantly increased hair growth in mice and showed potential as a natural treatment for alopecia.

This review highlights cepharanthine as a promising candidate for COVID-19 treatment due to its antiviral activity against SARS-CoV-2 and favorable pharmacokinetic and safety profile, but reports no new clinical results.

This study found that dexamethasone-loaded Eudragit® L 100 nanoparticles displayed controlled drug release depending on pH levels, with minimal toxicity to human fibroblasts.

This study demonstrated that a new topical treatment using ketotifen-loaded microneedles, designed for prolonged release, significantly reduced inflammatory markers in an animal model of allergic conjunctivitis, suggesting enhanced therapeutic delivery and sustained ocular benefits.

This review discusses recent advances in using nanocarrier-loaded gels for various medical applications and reports no new clinical results, highlighting potential advantages in therapeutic strategies.

This review examines the main absorption sites and influencing factors for orally administered drugs, highlighting variables such as solubility and gastrointestinal conditions that affect drug absorption in the small intestine and the development of effective drug delivery systems.

This study found that minoxidil exhibits preferential solvation by water in both water-rich and ethanol-rich solvent mixtures.

This review highlights the promising potential of microemulsions and nanoemulsions in (trans)dermal drug delivery, noting a gap in understanding their distinct mechanisms and composition-related effects on skin permeability, while emphasizing the limited clarity on mesostructures and cosolvent impacts.