15 citations
,
October 2020 in “Journal of Nanomaterials” This review discusses the potential of strontium-containing electrospun nanofibers for bone tissue engineering, outlining their effects on various cell types and highlighting current research challenges and future perspectives in the field.
9 citations
,
January 2023 in “Langmuir” This study presents a method for directly measuring the solubility of solid chemicals in the skin's stratum corneum under various humidity conditions, emphasizing its importance for dermal drug delivery and chemical safety assessments.
8 citations
,
January 2024 in “Regenerative Biomaterials” This study found that a novel bioceramic/alginate hydrogel with photothermal properties and multiple ion release effectively reduces infection and inflammation, and enhances osseointegration in early-stage peri-implant lesions, potentially improving dental implant survival rates.
8 citations
,
March 2023 in “Polymers” This study suggests that a chitosan-coated omeprazole-loaded nanoemulgel formulation may effectively treat certain skin infections due to its demonstrated antimicrobial properties and enhanced antibacterial activity.
7 citations
,
August 2021 in “ChemEngineering” This study found that Soluplus and L-ascorbyl 2,6-dipalmitate nanoparticles may improve minoxidil's skin permeability through stable hydrophobic interactions, enhancing its potential for targeted skin application.
6 citations
,
May 2022 in “Journal of Organometallic Chemistry” This study developed a catalytic system using indenyl-molybdenum(II)-bipyridine complexes and ionic liquid solvents to achieve a 95% yield of campholenic aldehyde from α-pinene oxide under mild conditions.
3 citations
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May 2025 in “Carbohydrate Polymers” In this study, researchers developed a dissolvable microneedle patch containing baricitinib for alopecia areata treatment, reporting significantly higher hair growth in mouse models compared to controls, suggesting its potential as an effective, pain-free topical therapy.
2 citations
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July 2023 in “Cosmetics” In this study, researchers highlighted that while hair lipids are crucial for hair health and protection, surfactants in shampoos and conditioners can partially remove these lipids, potentially affecting hair structure, though the exact mechanisms remain poorly understood and require further investigation.
2 citations
,
August 2021 in “Experimental and Therapeutic Medicine” This study suggested that moxibustion treatment before or at the early stage of diminished ovarian reserve in rats may improve ovarian function by modulating androgen balance, though its effects differ across intervention timings.
1 citations
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December 2024 in “ACS Biomaterials Science & Engineering” The patches could quickly deliver epilepsy treatment and reduce seizures.
1 citations
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January 2022 in “Contrast Media & Molecular Imaging” Levofloxacin and metronidazole reduce inflammation and speed up healing in gingival wounds.
January 2026 in “Pharmaceutics” This review highlighted recent advances in nanocarrier-based topical delivery systems for skincare, emphasizing their potential to enhance ingredient stability, penetration, and targeted release while addressing specific pathophysiological skin concerns.
December 2025 in “Processes” This study found that minoxidil had the highest solubility in shea butter, stearic acid, and rosemary oil, suggesting these natural oils may improve drug loading and encapsulation efficiency in lipid nanocarrier formulations for potential hair growth applications.
September 2025 in “Frontiers in Pharmacology” This study found that the meropenem-loaded spanlastic formulation showed strong potential as an effective topical therapy for bacterial skin infections in non-diabetic mice, demonstrating superior therapeutic activity and wound healing compared to free meropenem.
October 2024 in “Journal of Advanced Pharmaceutical Technology amp Research” This study found that nanoparticulate trigonelline formulations significantly improved hair length and density in rats with induced alopecia compared to controls and commercial hair oil, though it was not more effective than minoxidil after 30 days.
19 citations
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January 2022 in “Journal of Nanomaterials” This study concluded that an adapalene nanohydrogel containing Tween-80 could be a promising and stable topical treatment option for acne vulgaris due to enhanced skin permeability and stability compared to other formulations.
7 citations
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December 2024 in “International Journal of Pharmaceutics” In this study, researchers developed a new method for producing dissolving microneedle array patches containing mesoporous silica nanoparticles, successfully confirming nanoparticle deposition and release in both ex vivo and in vivo models.
January 2025 in “Journal of Materials Chemistry B” This research highlights the potential of using nanomaterials with advanced reactive oxygen properties to target oxidative stress in hair follicle tissue, which is associated with androgenetic alopecia, addressing a gap in the current understanding of AGA treatments.
61 citations
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April 2023 in “Bioactive Materials” This review article highlights recent advances in microneedle technology for wound healing and tissue regeneration, discussing various cargo types, structural designs, and fabrication methods, and suggesting guidelines for designing microneedle systems tailored to specific applications.
13 citations
,
November 2022 in “Biomaterials Science” This study demonstrated that a device combining hyaluronic acid-based dissolving microneedles and lipid polymer hybrid nanoparticles effectively delivered miR-218 to promote hair growth in a shaved mouse model, outperforming topical smear treatment without safety concerns.
13 citations
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September 2022 in “Materials & design” This study found that astaxanthin-loaded mucoadhesive patches effectively promoted recovery of oral premalignant lesions in vivo without the side effects seen with clinical tretinoin cream.
1 citations
,
August 2023 in “Advanced Drug Delivery Reviews” This review discusses various microneedle technologies for long-acting drug delivery, highlighting design considerations and challenges in bringing these minimally invasive devices to market, but it reports no new clinical results.
1 citations
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April 2023 in “Biomaterials advances” In this study, researchers developed gellan gum hydrogels functionalized with biomimetic peptides that create a supportive microenvironment for human dermal papilla cells, enhancing their hair-inductive capacity and ability to mimic hair morphogenesis-like events in vitro.
1 citations
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March 2023 in “Phytochemistry Reviews” This review discusses the potential of CBD for treating skin disorders, the challenges of its topical administration, and current strategies to improve its application, but reports no new clinical findings.
February 2025 in “Advanced Composites and Hybrid Materials” This study reported that in animal studies of androgenetic alopecia, a biodegradable microneedle patch releasing glutamic acid promoted hair regeneration more effectively than daily minoxidil, with higher hair follicle counts and less frequent dosing, showing the potential for clinical application.
36 citations
,
January 2014 in “Elsevier eBooks” This narrative review discusses the structure and functions of the skin, focusing on its barrier role, self-repair, thermoregulation, and immune functions, and reports no new experimental results.
12 citations
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July 2020 in “International Journal of Pharmaceutics” This study found that finasteride- and dutasteride-loaded iron oxide nanoparticles improved drug penetration in the skin, suggesting they may be promising for topical alopecia therapies.
25 citations
,
June 2011 in “International journal of pharmaceutics” This study found that polymeric nanoparticle suspensions can deliver poorly water-soluble drugs to hair follicles in animal models, suggesting a promising method for targeted topical treatments.
38 citations
,
August 2012 in “Biochemical and biophysical research communications” This study found that leukocytes and beard hair follicle cells have an endogenous circadian clock, with PER1 and PER3 expression possibly serving as biomarkers for assessing individual biological clock traits.
25 citations
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January 2013 in “Journal of Industrial and Engineering Chemistry” This study found that cubosomal suspensions significantly enhanced the hair growth-promoting effects of Thuja orientalis, Polygonum multiflorum Thunberg, and Espinosilla extracts in a mouse model, making them as effective as Minoxidil.