44 citations
,
January 2006 in “Biological & Pharmaceutical Bulletin” This research suggests that testosterone-induced expression of TGF-beta1 and type I procollagen may lead to perifollicular fibrosis in androgenetic alopecia, with finasteride inhibiting this process as a possible mechanism for its effects.
43 citations
,
July 2019 in “Stem Cells International” This review discusses advances and challenges in skin tissue engineering, focusing on developing 3D constructs for functional skin substitutes, and reports no new clinical results.
41 citations
,
September 2017 in “Advanced Healthcare Materials” This study found that the DexIEME hydrogel promotes complete skin regeneration and scar attenuation in murine and porcine models, suggesting potential for treating deep dermal injuries.
37 citations
,
December 2024 in “Theranostics” In this study, a newly developed nanoparticle-loaded hydrogel wound dressing demonstrated significant antibacterial, antioxidant, anti-inflammatory, and proangiogenic activities, effectively reducing pain and promoting healing in a murine burn wound model while preventing infection by *Staphylococcus aureus*.
33 citations
,
December 2012 in “NMR in Biomedicine” This study reports that microencapsulation of therapeutic cells with contrast agents enables visualization across multiple imaging modalities, potentially improving cellular immunoprotection and tracking after transplantation.
28 citations
,
September 2020 in “Pharmaceutics” This review discusses the potential of three-dimensional printed mesoporous scaffolds for drug delivery applications, particularly for bone cells and tissues, but reports no new clinical results.
25 citations
,
September 2006 in “Birth Defects Research” This article discusses various skin pattern formations, their molecular mechanisms, and highlights the need for further understanding to connect molecular biology with organism phenotypes, without providing new clinical findings.
24 citations
,
June 2018 in “Expert Review of Pharmacoeconomics & Outcomes Research” This review discusses the potential of microneedle arrays for drug delivery and in the cosmetic market, but reports no new clinical results; factors for commercial therapeutic use are explored.
19 citations
,
September 2020 in “Pharmaceutics” This study investigated a new formula called SV-loaded nanospanlastics for topical application to treat androgenic alopecia. It showed similar effectiveness to minoxidil lotion but with fewer adverse effects when used to enhance dermal delivery and efficacy of sodium valproate.
18 citations
,
August 2019 in “Drug Development and Industrial Pharmacy” This study concludes that phospholipid–polymer hybrid nanoparticles may be an effective delivery system for quercetin in treating androgenic alopecia by improving hair regrowth and preventing hair follicle cell apoptosis in rat models.
17 citations
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January 2019 in “Journal of cancer” This study found that the medicinal formula YH0618 may reduce toxicity from the chemotherapy drug doxorubicin, improving side effects like hair loss and organ damage, while maintaining its anti-cancer effects.
17 citations
,
October 2016 in “Artificial Cells Nanomedicine and Biotechnology” This study found that arginine-loaded lipidic nanoparticles improved hair follicle growth in male hamsters more effectively than an aqueous arginine solution.
14 citations
,
July 2017 in “Monatshefte für Chemie - Chemical Monthly” This review discusses the analysis of pharmaceutical relics from prehistoric times to the twentieth century and emphasizes the need for a multifaceted approach, but it presents no new experimental results.
14 citations
,
December 2011 in “Archives of Dermatological Research” This study found that phyto-vesicles of ß-sitosterol showed better absorption and improved activity for treating androgenetic alopecia in rats compared to the compound and its complex.
11 citations
,
January 2013 in “Methods in molecular biology” This study describes a method for labeling and tracking hair follicle stem cells in mouse skin using a Cre/lox recombination system with tamoxifen, providing insights into stem cell behavior and contribution to tissue regeneration.
10 citations
,
December 2020 in “Dermatologic Therapy” This study found that topical minoxidil 5% gel and spironolactone 1% gel were both effective treatments for androgenetic alopecia, with a combination of both providing the best clinical response and achieving 100% effectiveness among participants.
10 citations
,
June 2016 in “Wound Repair and Regeneration” This review explores the regenerative potential of hair follicles and their role in complete skin regeneration, emphasizing the influence of mechanical factors and niche signaling pathways on hair growth and loss.
10 citations
,
January 2014 in “Chemical and Pharmaceutical Bulletin” This study found that hair follicle-plugging reduced skin permeation of certain model drugs, with effects varying based on EtOH pretreatment and the drug being evaluated.
5 citations
,
February 2014 in “Journal of Liquid Chromatography & Related Technologies” This study successfully developed and validated a reverse-phase HPLC method for accurately determining finasteride and tamsulosin simultaneously in bulk and pharmaceutical formulations.
5 citations
,
November 1992 in “Current problems in dermatology” This review discusses the role of glucocorticoids in treating severe inflammatory disorders and highlights their potential adverse effects, recommending dosage management to minimize these risks; no new clinical results are reported.
4 citations
,
February 2024 in “Scientific Reports” This study found that Platelet Rich Plasma is effective as a direct pulp capping agent, comparable to Mineral Trioxide Aggregate, but with potentially better cellular dentinogenic responses and homogenous tissue formation in dogs.
4 citations
,
January 2021 in “Dermatology Review” This review discusses the role of Demodex mites in ocular demodecosis and various eye ailments, highlighting diagnostic methods but noting a lack of standardized treatments, with no new clinical results reported.
3 citations
,
September 2018 in “Journal of Biomaterials Science, Polymer Edition” This study found that pyramidal neural precursors best grew neurites on matrigel, while neural stem cells differentiated directionally on aligned fibrin, suggesting the importance of biomaterial selection for cell culture.
2 citations
,
August 2020 in “Cosmetics” This study reported unexpected positive results in two males with androgenetic alopecia using a cyclodextrin-enabled, natural-based formula over 270 days, showing marked hair thickening and reduced scalp hair loss.
1 citations
,
October 2025 in “Nano Research” In this study, researchers developed a dissolvable microneedle patch combining HA-TEMPO and Portulaca oleracea L.-derived nanoparticles, which effectively reduced oxidative stress and inflammation in an atopic dermatitis model while restoring immune balance, suggesting a promising treatment strategy.
1 citations
,
March 2025 in “Biomedical Journal of Scientific & Technical Research” This publication overview describes the Biomedical Journal of Scientific & Technical Research's rigorous peer review process and their focus on genetic, biomedical, and technical knowledge research within an open access format, but does not report specific study results.
1 citations
,
January 2025 in “BIO Integration” This review highlights that the combination of ultrasound and microneedles can enhance transdermal drug delivery by using physical and energy-driven mechanisms to improve drug penetration into deeper skin layers, with implications for precision medicine and chronic disease treatments.
1 citations
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March 2024 in “Signal transduction and targeted therapy” In this review, researchers explored the multifaceted role of NF-κB signaling in various biological processes and diseases, including its interactions with other pathways, and discussed possible therapeutic approaches targeting this pathway for treating conditions like cancer, autoimmune disorders, and COVID-19.
1 citations
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January 2022 in “Pharmaceutical Sciences Asia” This review highlights the potential of microneedles as a low-cost, well-tolerated method for transdermal drug delivery in dermatology, though further research is needed to establish their clinical efficacy.
1 citations
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January 2021 in “Open Access Journal of Cancer & Oncology” In this study, the Trivedi Effect®-Consciousness Energy Healing Treatment was reported to significantly increase the solubility and isotopic abundance ratios of flutamide, potentially improving its stability and efficacy.