10 citations,
May 2020 in “Frontiers in cell and developmental biology” MicroRNAs are important for hair growth regulation, with Dicer being crucial and Tarbp2 less significant.
10 citations,
September 2019 in “Experimental Eye Research” The enzyme RDH12 plays a role in vision and retinal disease, with mutations leading to early onset visual loss and blindness, but the exact disease mechanism is unclear and there are no treatments yet.
10 citations,
January 2010 in “International journal of trichology” Keratin-associated proteins are part of the developing hair fiber cuticle.
9 citations,
September 2019 in “PLoS ONE” K42 and K124 keratins are only found in horse hoof lamellae.
6 citations,
March 2018 in “Hair transplant forum international” The Graft Quality Index grades hair transplant grafts to predict placement difficulty and surgery results.
4 citations,
October 2022 in “Microbial Cell Factories” Certain bacteria from the Citrullus colocynthis plant may be a new source of antibiotics to fight drug-resistant diseases.
2 citations,
May 2010 in “Hair transplant forum international” Different hair restoration techniques like follicular unit extraction, scalp reduction, and body hair transplantation can improve results for patients unhappy with their initial surgery, but they also have potential risks.
1 citations,
January 2020 in “Microscopy research” Researchers successfully grew hair follicle stem cells from mice and humans, which could be useful for tissue engineering and regenerative medicine.
April 2024 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” Retinoic acid helps activate hair growth in people with common hair loss by working on a specific cell growth pathway.
April 2024 in “Applied biological chemistry” Piperine from black pepper can make hair less oily by blocking fat cell development in hair roots.
Transplanted rat hair follicles grew hair and had increased but not fully restored nerve connections in mice.
ILC1-like cells can independently cause alopecia areata by affecting hair follicles.
Deleting the MAD2L1 gene is tolerated in certain mouse cancer models.
Deleting the MAD2L1 gene in mice led to rapid tumor growth despite chromosomal instability.
July 2013 in “Hair transplant forum international” Dr. James Harris successfully incorporated Follicular Unit Extraction into his hair restoration practice, offering more surgical options and achieving natural results with the help of a team approach.
April 2023 in “Chinese Medical Journal” Human hair follicle stem cells help repair tendon injuries.
550 citations,
December 2005 in “The Journal of clinical investigation/The journal of clinical investigation” Researchers successfully isolated and identified key markers of stem cell-enriched human hair follicle bulge cells.
235 citations,
January 2011 in “Journal of Clinical Investigation” Men with baldness due to androgenetic alopecia still have hair stem cells, but lack specific cells needed for hair growth.
99 citations,
September 2007 in “The American journal of pathology” Chemotherapy damages hair follicles, causing hair loss and other cellular changes.
92 citations,
November 2006 in “Proceedings of the National Academy of Sciences of the United States of America” BMP signaling controls hair follicle size and cell growth by affecting cell cycle genes.
80 citations,
September 2007 in “Cell Cycle” Stem cells in hair follicles can become various cell types, including neurons.
70 citations,
February 2016 in “EMBO reports” Scientists found a specific group of itch-sensing nerve cells in mice important for feeling itch but not for sensing heat or touch.
45 citations,
October 2015 in “BMC Genomics” Chicken feather growth involves specific genes and shares similarities with hair development.
39 citations,
November 2007 in “Experimental dermatology” Human hair follicles contain a complex network of prostanoid receptors that may influence hair growth.
35 citations,
August 2009 in “Differentiation” Desmoglein 4 is controlled by specific proteins that affect hair growth.
32 citations,
April 2017 in “Scientific Reports” Platelet-rich plasma can help grow more mouse hair follicles, but it doesn't work for human hair follicles yet.
29 citations,
October 2017 in “Journal of proteomics” The research found specific proteins that affect fiber characteristics and hair growth in sheep and goats.
29 citations,
April 2003 in “Experimental dermatology” Human hair follicles grown in vitro maintain normal keratin patterns and structure.
26 citations,
September 2012 in “Cell Reports” B-Raf and C-Raf are essential for maintaining melanocyte stem cells to prevent hair graying.
26 citations,
August 2008 in “Clinical endocrinology” The document concludes that more multidisciplinary research is needed to understand and treat PCOS, a condition that significantly affects women's health and quality of life.