research Cutaneous Manifestations of Polycystic Ovarian Disease
Skin problems like excessive hair growth, acne, and dark skin patches can be signs of Polycystic Ovarian Disease, which may also be linked to family history and a risk for diabetes.
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research Metabolic Syndrome, Cardiovascular Disease, and the Hair Growth Cycle: Addressing Hair Growth Disruptions Using Nourkrin with Marilex as a Proteoglycan Replacement Therapy: A Concise Review
Nourkrin® with Marilex® may significantly increase hair growth and alopecia could be an early sign of metabolic syndrome.
research Examining Cutaneous Disease Activity as an Outcome Measure for Clinical Trials in Dermatomyositis
Skin disease activity scores can help decide when skin symptoms no longer affect the quality of life in patients with mild dermatomyositis.
research Male-Pattern Baldness and Its Association with Coronary Heart Disease
Male-pattern baldness has a weak link to heart disease and some related health conditions.
research Graves' Disease: An Unusual Cause of Pediatric Alopecia Areata
Graves' disease can cause hair loss in children and should be considered when treating pediatric alopecia areata.
research The Princeton III Consensus Recommendations for the Management of Erectile Dysfunction and Cardiovascular Disease
The Princeton III Consensus recommends assessing cardiovascular risk in men with erectile dysfunction and prioritizing heart health before treating ED, especially in those with potential heart disease.
research The Incidence and Types of Alopecia in Patients With Thyroid Disease
Women with thyroid disease are more likely to experience female pattern hair loss, especially if they've had thyroid disease for a long time.
research Metabolic Disease With Autoimmune Phenomena: Two Cases of SLE-Like Disease in Young Children Diagnosed With Lysinuric Protein Intolerance
The document described two cases of young children with lysinuric protein intolerance, a rare metabolic disease, presenting with symptoms resembling systemic lupus erythematosus (SLE). The first case involved a boy with failure to thrive and various symptoms, including hemolytic uremic syndrome-like disease and lupus nephritis, who tested positive for several autoantibodies. The second case was a Turkish girl with polyarthritis, fatigue, diffuse hair loss, and other symptoms, also showing positive autoantibodies. Both children were diagnosed with a lupus-like disease and treated with immunosuppressive therapy. Metabolic studies revealed low serum levels and high urine levels of arginine, lysine, and ornithine, leading to the diagnosis of lysinuric protein intolerance. The second case was confirmed by identifying a new mutation in the SLC7A7 gene.
research Alopecia and Thyroid Disease
Thyroid disease can cause hair loss and treating thyroid problems might help with hair disorders.
research Hair Abnormalities and Neurological Disease
Hair changes could indicate neurological diseases and help monitor treatment.
research Correlation of Androgenetic Alopecia and Early Onset Coronary Heart Disease in Men
Men with early-onset baldness may have a higher risk of heart disease.
research Faculty Opinions Recommendation of Association of Androgenetic Alopecia with Mortality from Diabetes Mellitus and Heart Disease
People with moderate or severe hair loss are at a higher risk of dying from diabetes and heart disease.
research Androgens and Cardiovascular Disease
Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.
research American Association of Clinical Endocrinologists, American College of Endocrinology, and Androgen Excess and PCOS Society Disease State Clinical Review: Guide to the Best Practices in the Evaluation and Treatment of Polycystic Ovary Syndrome - Part 1
The guide recommends specific methods for diagnosing PCOS and various treatments for its symptoms, while considering the health impacts on adolescents.
research Anti-TNF Antibody-Induced Psoriasiform Skin Lesions in Patients with Inflammatory Bowel Disease Are Characterised by Interferon-γ-Expressing Th1 Cells and IL-17A/IL-22-Expressing Th17 Cells and Respond to Anti-IL-12/IL-23 Antibody Treatment
Anti-IL-12/IL-23 antibody therapy effectively treats psoriasiform skin lesions in IBD patients.
research DrugNet: Network-Based Drug–Disease Prioritization by Integrating Heterogeneous Data
DrugNet effectively identifies new uses for existing drugs and may save resources in drug development.
research Budesonide for Maintenance of Remission in Crohn's Disease
Budesonide is not effective for maintaining remission in Crohn's disease beyond three months.
research WNT Signaling in Disease
The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.
research Skin Manifestations of Celiac Disease
A gluten-free diet significantly improves skin and health issues in people with dermatitis herpetiformis, a skin condition linked to celiac disease.
research Recognition and Management of Staphylococcus Aureus Toxin-Mediated Disease
Early detection and intensive treatment of diseases caused by Staphylococcus aureus toxins are crucial for reducing severe health effects.
research Increased Androgen Bioavailability Is Associated With Non-Alcoholic Fatty Liver Disease In Women With Polycystic Ovary Syndrome
Women with PCOS and higher androgen levels are more likely to have fatty liver disease.
research Polycystic Ovary Syndrome, Androgen Excess, and the Risk of Nonalcoholic Fatty Liver Disease in Women: A Longitudinal Study Based on a United Kingdom Primary Care Database
Women with PCOS are more than twice as likely to develop nonalcoholic fatty liver disease.
research Nonalcoholic Fatty Liver Disease and Polycystic Ovary Syndrome
People with PCOS, especially if obese, often have NAFLD, linked to obesity, insulin resistance, and high androgen levels.
research Significant Correction of Disease After Postnatal Administration of Recombinant Ectodysplasin A in Canine X-Linked Ectodermal Dysplasia
Giving a special protein to dogs with a certain genetic disease improved their symptoms but didn't help with hair growth.
research Peripheral Arterial Disease: Diagnosis And Management
PAD is common but often missed, needing lifestyle changes and medication for better outcomes.
research Management of Endocrine Disease: Hyperandrogenism After Menopause
Doctors should check for serious tumor causes of high androgen levels in postmenopausal women and more research is needed on this condition.
research Acne and Systemic Disease
Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.
research Acne as a Chronic Systemic Disease
Acne is a chronic disease linked to various systemic conditions and has significant psychological and social effects.
research Keratins and Skin Disease: Genetic and Molecular Roles
Keratin mutations cause skin diseases and could lead to new treatments.
research Mechanisms of Disease: Selective Inhibition of 11β-Hydroxysteroid Dehydrogenase Type 1 as a Novel Treatment for Metabolic Syndrome
Blocking the enzyme 11β-HSD1 might help treat obesity and metabolic issues.