research Activating Wnt/β-Catenin Signaling Pathway for Disease Therapy: Challenges and Opportunities
Using drugs to activate the Wnt/β-catenin pathway has potential for treating diseases but also presents challenges.
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660-690 / 1000+ results research Vitamin D and Aging
Balanced vitamin D levels are crucial to delay aging and prevent related diseases.
research Growth Factors in Hair Organ Development and the Hair Growth Cycle
Growth factors are crucial for hair development and could help treat hair diseases.
research Targeting Integrin Pathways: Mechanisms and Advances in Therapy
New therapies are being developed that target integrin pathways to treat various diseases.
research Skin Keratins
Keratins are important for skin cell health and their problems can cause diseases.
research Wnt Signaling: The Good and the Bad
Wnt signaling is important for development and cell regulation but can cause diseases like cancer when not working properly.
research JAK-Inhibitors in Dermatology: Current Evidence and Future Applications
JAK-inhibitors are effective for treating psoriasis and show promise for other skin diseases.
research Epidermal Differentiation Complex: A Review on Its Epigenetic Regulation and Potential Drug Targets
Understanding how EDC genes are regulated can help develop better drugs for skin diseases.
research Syphilis: The Great Imitator
Syphilis has a wide range of symptoms that can look like other diseases, and if not treated, it can progress to a more serious stage, especially in HIV-positive patients.
research The Influence of Interferon on Healthy and Diseased Skin
Type I interferons play a key role in the development of various skin diseases.
research Thyroid Hormone Action on Skin
Thyroid hormones are important for skin health and might help treat skin diseases, but more research is needed to understand their effects fully.
research Men And Women, So Different, So Similar: Observations From Cross-Sex Hormone Treatment Of Transsexual Subjects
Cross-sex hormone treatment in transsexual individuals helps understand how sex hormones affect diseases like heart disease and diabetes.
research Role of Beta-Catenin Activation Levels and Fluctuations in Controlling Cell Fate
Proper control of β-catenin activity is crucial for development and preventing diseases like cancer.
research The Use of Auto-Antibody Testing in the Evaluation of Interstitial Lung Disease: A Practical Approach for the Pulmonologist
Auto-antibody testing is a useful but not definitive tool in diagnosing interstitial lung diseases, and using a specific algorithm could make testing more cost-effective.
research Genetic Control of Cytokines
Genes affect cytokine production, which can influence chronic diseases, and certain interventions may help prevent related molecular damage.
research Vitamin D And The Skin: A Review For Dermatologists
Vitamin D is important for skin health and can affect various skin diseases.
research Efficient In Vitro Transfection of Human Keratinocytes with an Adenovirus-Enhanced Receptor-Mediated System
The AVET system effectively delivers genes to human keratinocytes and may help treat skin diseases.
research Recent Updates on Wnt Signaling Modulators: A Patent Review (2014-2020)
New patents show progress in developing drugs targeting the Wnt pathway for diseases like cancer and hair loss.
research A Review on the Chemical Constituents and Pharmacological Efficacies of Lindera Aggregata (Sims) Kosterm
Lindera aggregata has many beneficial compounds that can help prevent and manage diseases.
research Male Equivalent Polycystic Ovarian Syndrome: Hormonal, Metabolic, and Clinical Aspects
Men with hormonal imbalances similar to PCOS may have increased risk of metabolic and heart diseases.
research Epidemiology of Vitiligo: A Dual Population-Based Approach
Vitiligo is underreported in medical claims and is linked to certain skin types and autoimmune diseases.
research Reversible Alopecia in Vogt-Koyanagi-Harada Disease and Sympathetic Ophthalmia
Alopecia can be reversed with timely steroid treatment in VKH and SO diseases.
research Non-Invasive Human Skin Transcriptome Analysis Using mRNA in Skin Surface Lipids
A new non-invasive method can analyze skin mRNA to understand skin diseases better.
research Rodent Models in Placental Research: Implications for Fetal Origins of Adult Disease
Using rodents for research shows that health problems in the womb can cause diseases later in life.
research Keratin Function and Regulation in Tissue Homeostasis and Pathogenesis
Keratin is crucial for keeping skin cells healthy and its changes can lead to diseases and affect cell behavior.
research Evolution of Ritlecitinib Population Pharmacokinetic Models During Clinical Drug Development
Ritlecitinib shows promise as a versatile treatment for various autoimmune and inflammatory diseases.
research Homology Modeling of 5-Alpha-Reductase 2 Using Available Experimental Data
Accurate protein modeling can help develop new treatments for prostate cancer and other diseases.
research Higher Prevalence of Clinical Cardiovascular Comorbidities in Postmenopausal Women with Self-Reported Premenopausal Hirsutism and/or Oligo-Amenorrhea
Postmenopausal women with past hirsutism or irregular periods have more heart and lung diseases.
research Resident Macrophages of the Lung and Liver: The Guardians of Our Tissues
Lung and liver macrophages protect our tissues and their dysfunction can cause various diseases.
research Lymphatic Vessel: Origin, Heterogeneity, Biological Functions, and Therapeutic Targets
Lymphatic vessels are essential for health and can be targeted to treat various diseases.