research Drug Repurposing: Hypothesis, Molecular Aspects, and Therapeutic Applications
Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.
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research Venous Thromboembolism and Women's Health
Women have a higher risk of blood clots from hormonal factors and need careful treatment, especially during pregnancy.
research Loss of Epidermal Melanin Unit Integrity in Human Skin During Melanoma Genesis
Melanoma development can be linked to the breakdown of skin's melanin-producing units.
research Fibroblast Heterogeneity and Functions: Insights from Single-Cell Sequencing in Wound Healing, Breast Cancer, Ovarian Cancer, and Melanoma
Different types of fibroblasts play specific roles in wound healing and cancer, which could help improve treatments.
research Nutraceuticals Known to Promote Hair Growth Do Not Interfere With the Inhibitory Action of Tamoxifen in MCF7, T47D and BT483 Breast Cancer Cell Lines
Nutraceuticals that promote hair growth do not reduce tamoxifen's effectiveness in breast cancer treatment.
research Causes and Management of Pica Disorder Among Central Iraqi Peoples
Pica disorder in central Iraq is mainly found in females and is linked to low iron levels; treatment with iron improves most patients.
research The Molecular Pathogenesis of Trichilemmal Carcinoma
Trichilemmal carcinoma shares genetic traits with other skin cancers, suggesting similar treatment options.
research The Molecular Pathogenesis of Trichilemmal Carcinoma
Trichilemmal carcinoma shares genetic traits with other skin cancers, suggesting similar treatment options.
research Sex Hormones and Related Compounds, Including Hormonal Contraceptives
The document concludes that sex hormones and related compounds have various effects on health, with both potential benefits and risks.
research Forum
The document concludes that various medications and treatments can have significant, sometimes adverse, effects on health outcomes.
research Efficacy and Safety of Docetaxel in the Elderly
Docetaxel is safe and works well for older people with cancer, with manageable side effects.
research Abstract 2962: Chemotherapy-Induced Senescence Drives Peripheral Neuropathy
Eliminating senescent cells can prevent and reverse chemotherapy-induced peripheral neuropathy.
research A Cross-Sectional Study of Clinical, Dermoscopic, Histopathological, and Molecular Patterns of Scalp Melanoma in Patients With or Without Androgenetic Alopecia
Scalp melanoma is more common and easier to diagnose early in people with androgenetic alopecia due to sun damage.
research Melanoma: Genetic Abnormalities, Tumor Progression, Clonal Evolution, And Tumor-Initiating Cells
Melanoma's complexity requires personalized treatments due to key genetic mutations and tumor-initiating cells.
research Efficacy of Albumin-Bound Paclitaxel Combined with Nedaplatin in Neoadjuvant Therapy for Esophageal Squamous Cell Carcinoma: A Single-Center Retrospective Observational Study
The combination therapy is effective and well-tolerated for treating esophageal cancer.
research ST14 Interacts With TMEFF1 and Is a Predictor of Poor Prognosis in Ovarian Cancer
High levels of ST14 and TMEFF1 proteins in ovarian cancer are linked to worse patient outcomes and may be a new treatment target.
research FLCN, A Novel Autophagy Component, Interacts With GABARAP And Is Regulated By ULK1 Phosphorylation
The protein FLCN is involved in cellular cleanup and is regulated by ULK1.
research Skin Cancer: Understanding the Transformation from Conventional to Advanced Treatment Approaches
New treatments like nanotechnology show promise in improving skin cancer therapy.
research Logic-Based Modeling and Drug Repurposing for the Prediction of Novel Therapeutic Targets and Combination Regimens Against E2F1-Driven Melanoma Progression
Tadalafil and Finasteride may help treat aggressive melanoma.
research The Molecular Pathogenesis of Trichilemmal Carcinoma
Trichilemmal carcinoma shares genetic changes with other skin cancers, suggesting similar causes and potential treatments.
research The Potential Impact of Melanosomal pH and Metabolism on Melanoma
Melanin may help melanoma cells grow by aiding their metabolism.
research Oral Presentations: Abstracts of the Urological Society of Australia and New Zealand Annual Scientific Meeting, Melbourne, Australia
Urologists should monitor mental health in patients taking finasteride due to potential links to suicidal thoughts, adjusting dosage or stopping use if necessary. More research is needed to confirm if finasteride causes these thoughts.
research Signal Integrator Function of CXXC5 in Cancer
CXXC5 can both suppress and promote cancer, making it a complex target for treatment.
research Clinical Applications of Antiandrogens
Antiandrogens are effective for conditions like prostate cancer and skin issues, but more research is needed to confirm their benefits and minimize side effects.
research Treatment of Lichen Planopilaris and Frontal Fibrosing Alopecia: A Retrospective, Real-Life Analysis in a Tertiary Center in Germany
Systemic treatments like hydroxychloroquine and cyclosporine A help with Lichen Planopilaris and Frontal Fibrosing Alopecia, but ongoing treatment is needed.
research Gemcitabine in Combination with Vinorelbine in Elderly Patients with Anthracycline- and Taxane-Pretreated Metastatic Breast Cancer
The combination of gemcitabine and vinorelbine is effective and safe for treating elderly patients with advanced breast cancer previously treated with anthracyclines and taxanes.
research Local Heroes or Villains: Tissue-Resident Memory T Cells in Human Health and Disease
Tissue-resident memory T cells can protect against infections and cancer but may also contribute to autoimmune diseases.
research Androgen- and Estrogen-Secreting Adrenal Cancers
Rare adrenal cancers that secrete androgens or estrogens have a poor prognosis and are treated primarily with surgery.
research Present and Future Use of Exosomes in Dermatology
Exosomes could be key in treating skin conditions and healing wounds.
research Microsurgical Reconstruction of Extensive Scalp Defects
Microsurgical reconstruction effectively covers complex scalp defects but doesn't improve survival for cancer-related cases.