January 1994 in “European Journal of Cancer” The European School of Oncology organized various educational events in 1994, highlighting important cancer research findings.
December 1992 in “Reviews in Medical Virology” The review concluded that restrictions on people with HIV/AIDS often violated their rights without proven effectiveness in stopping the virus, highlighting education as the best control method.
January 1977 in “Case Reports in Medicine” This article discusses ovarian steroid cell tumors, which can produce testosterone and manifest symptoms like hirsutism, emphasizing surgery as the primary treatment, but reports no new clinical findings.
November 2020 in “Psychoneuroendocrinology” In this study, repeated finasteride administration was associated with decreased social interaction and cognitive deficits in male rats, potentially linked to changes in cholinergic system activity.
467 citations
,
October 2014 in “European Journal of Endocrinology” This paper reviews the diagnostic criteria, etiological factors, and treatment approaches for PCOS, highlighting the importance of considering metabolic issues such as insulin resistance and obesity, but reports no new findings.
243 citations
,
September 2016 in “Dermatology and Therapy” This article provides an overview of how dermoscopy can aid in the noninvasive diagnosis of various general dermatological disorders, grouped by clinical presentation, but reports no new clinical results.
187 citations
,
April 2019 in “npj Regenerative Medicine” This study found that hMSC secretomes from umbilical cord Wharton's jelly had the most potent angiogenic effects, whereas those from adipose tissue demonstrated the weakest angiogenic potential.
127 citations
,
December 2005 in “Experimental Dermatology” This study provides evidence that psychoemotional stress inhibits hair growth in mice by affecting the brain-hair follicle axis, with specific neuropeptides and treatments modulating this effect.
110 citations
,
July 2010 in “Journal of The American Academy of Dermatology” Hair loss linked to higher heart disease risk in both men and women.
84 citations
,
February 2013 in “Clinica chimica acta” This review presents evidence that correlations exist between hair mineral imbalances and various diseases, though inconsistencies in results highlight the need for standardized preparation methods.
72 citations
,
October 2010 in “Journal of The American Academy of Dermatology” This study concluded that iron deficiency is common among women but not more prevalent in those with female pattern hair loss or chronic telogen effluvium compared to control subjects without hair loss.
69 citations
,
April 2010 in “British Journal of Dermatology” This study found a significant association between androgenetic alopecia and metabolic syndrome, highlighting high-density lipoprotein cholesterol as a particularly important factor.
66 citations
,
February 2013 in “Pediatric Dermatology” This review summarizes the dermoscopic structures associated with infectious and inflammatory skin conditions and hair disorders in children but reports no new clinical results.
60 citations
,
June 1997 in “Journal of The American Academy of Dermatology” This review discusses the basic biology of apoptosis and its relevance to skin diseases, without presenting new research findings.
57 citations
,
January 2004 in “Journal of Endocrinology” This study found no support for the idea that male-pattern baldness in female-to-male transsexuals indicates an increased risk of coronary heart disease through androgenic effects on classic risk factors.
54 citations
,
October 2019 in “Australian Journal of General Practice” This article provides an updated overview of the diagnosis and management of tinea infections but reports no new clinical findings.
53 citations
,
September 2011 Other common signs, not just the well-known immune cells around hair bulbs, are important for diagnosing hair loss from alopecia areata.
49 citations
,
May 2013 in “JAMA Dermatology” This study found that moderate to severe androgenetic alopecia is an independent predictor of increased mortality risk from diabetes mellitus and heart disease in both sexes.
48 citations
,
August 2018 in “Nature Communications” This study found that JunB, a transcription factor, is crucial for maintaining epidermal-pilosebaceous stem cell homeostasis by regulating progenitor cell behavior and preventing sebaceous gland dysfunction.
48 citations
,
January 2018 in “Scientific Reports” This pilot study found that hair metabolome analysis may help differentiate pregnancy complications from healthy pregnancies by revealing significant metabolite differences between trimesters.
47 citations
,
March 2018 in “Journal of Pharmaceutical and Biomedical Analysis” This study identified 43 compounds in Platycladi Cacumen, including flavonoids, and found significant chemical variation in flavonoid content across different regions and processed products.
46 citations
,
June 2018 in “American Journal of Clinical Dermatology” This review summarizes the clinical, trichoscopic, and histopathological features of alopecia types associated with cutaneous and systemic lupus erythematosus and explores their links to disease activity, but it reports no new clinical results.
45 citations
,
November 2009 in “British Journal of Dermatology” This study found that women with early-onset androgenetic alopecia had higher aldosterone levels and blood pressure, suggesting a possible link to the increased prevalence of hypertension in this group.
42 citations
,
August 2017 in “Human Reproduction” This study observed that a longer anterior clitoral anogenital distance (AGDAC) is associated with polycystic ovary syndrome in adult Mediterranean women.
40 citations
,
May 2016 in “Proceedings of the National Academy of Sciences of the United States of America” This study found that the mechanical stiffening of the human hair follicle along the first millimeter is linked to changes in the keratin network architecture and composition during keratinization.
39 citations
,
May 2011 in “Human Immunology” This review discusses findings from genetic studies on acne, highlighting progress in understanding its molecular pathogenesis without reporting new clinical results.
39 citations
,
May 2010 in “Stem Cells” This study reported that disrupting ephrin-Eph interactions in adult mouse skin doubled cell proliferation in the hair follicle and epidermis, suggesting ephrins as negative regulators of proliferation.
38 citations
,
June 2018 in “Archives of Toxicology” This review suggests that skin may largely protect itself from CYP-generated reactive metabolites due to higher conjugating enzyme activities, while highlighting limitations in modeling human skin metabolism experimentally.
37 citations
,
January 2010 in “Acta dermato-venereologica” This study found that both men and women with androgenic alopecia had significantly higher triglycerides, total cholesterol, and LDL-C and lower HDL-C levels than controls, suggesting increased dyslipidemia prevalence.
36 citations
,
October 2022 in “ULTRASONOGRAPHY” This article reviews the expanding role of dermatologic ultrasonography in patient management for various skin conditions, highlighting its advantages over other imaging techniques, but reports no new findings.