19 citations
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November 2021 in “Lupus Science & Medicine” This study found that Black patients with discoid lupus erythematosus had significantly worse CLASI damage scores and higher odds for dyspigmentation, scalp involvement, and scarring alopecia compared to non-Black patients.
15 citations
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September 2014 in “Journal of The American Academy of Dermatology” This study found that seven cases of cicatricial alopecia initially diagnosed as discoid lupus erythematosus were more consistent with lichen planopilaris based on histopathology.
June 2018 in “Surgical Case Reports” S-1 treatment led to a complete response in pancreatic cancer with manageable side effects.
32 citations
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September 1989 in “Medical Clinics of North America” This review describes the types of skin lesions associated with systemic lupus erythematosus, discussing their histopathological features, serologic associations, pathogenesis, and prognostic implications.
This study found that lupus discoid lesions on the scalp are more common in females and are associated with a higher incidence of other autoimmune diseases compared to lesions in other areas.
February 2010 in “Emergency Medicine News” This case report describes a 36-year-old African American woman with discoid lupus resulting in skin lesions, highlighting the need for a multidisciplinary approach in managing cutaneous and systemic lupus symptoms.
11 citations
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January 2009 in “Acta Dermato Venereologica” In this case report, a 37-year-old man with discoid lupus erythematosus experienced around 80% hair regrowth after treatment with a combination of oral and topical therapies.
52 citations
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March 2010 in “British Journal of Dermatology” This study demonstrated the expression of type 1 interferon-related proteins in inflammatory lesions of alopecia areata, showing a distinct distribution pattern compared to cicatricial alopecia.
20 citations
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October 2016 in “Veterinary dermatology” This study reports that generalized discoid lupus erythematosus is a recognized canine variant of cutaneous lupus erythematosus, resembling its human counterpart, with varied treatment responses and common relapses.
15 citations
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March 2008 in “The Journal of Dermatology” In this case report, a patient with a history of discoid lupus erythematosus experienced an exacerbation of the condition after topical immunotherapy for alopecia areata, suggesting contact dermatitis as a potential trigger.
5 citations
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July 2023 in “International Journal of Women’s Dermatology” This study reports that anifrolumab showed promising improvement in a case of refractory discoid lupus erythematosus, specifically enhancing skin lesions and promoting hair regrowth, suggesting potential as an effective therapy for severe cases.
17 citations
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July 2019 in “Lupus Science & Medicine” In this study, gene expression analysis of plucked hair follicles from scalp lesions was sufficient to differentiate chronic discoid lupus erythematosus from psoriasis and healthy controls, suggesting a non-invasive diagnostic potential.
November 2024 in “International Medical Case Reports Journal” Glucocorticoid treatment in lupus can cause oral lesions, which need early diagnosis and comprehensive care.
132 citations
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July 2000 in “Lupus” This study found that chronic cutaneous lupus erythematosus with discoid lesions was the most common skin manifestation among patients with lupus erythematosus, while nonspecific skin lesions were linked to systemic lupus erythematosus, particularly during active disease phases.
16 citations
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June 2015 in “Seminars in Cutaneous Medicine and Surgery” This article discusses the challenges of diagnosing and managing hair disorders in patients with skin of color, especially conditions more prevalent in those of African descent, and provides no new clinical results.
12 citations
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March 2018 in “Anais brasileiros de dermatologia/Anais Brasileiros de Dermatologia” This article describes a case of frontal fibrosing alopecia in a patient with chronic lichenoid lupus erythematosus and notes the lack of similar documented cases in existing literature.
research Skin
2 citations
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January 2011 in “Elsevier eBooks” This review discusses approaches to diagnosing and managing cutaneous manifestations of lupus erythematosus and reports no new clinical results.
2 citations
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January 2004 in “Elsevier eBooks” This article reviews historical uses of the term "lupus" for various skin disorders but provides no new clinical findings.
1 citations
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March 2012 in “Indian Journal of Rheumatology” This study found that while alopecia is a less serious manifestation of lupus, it significantly impacts the quality of life due to its psychosocial effects.
January 2020 in “Clinical Case Reports and Reviews” This study observed that the coexistence of Frontal Fibrosing Alopecia and lupus erythematosus in a patient may suggest a shared pathogenic background.
April 2018 in “International Journal of Research in Dermatology” In this study, 82% of systemic lupus erythematosus patients at a tertiary care center in India exhibited skin manifestations, including photosensitivity, malar rash, discoid rash, and oral ulcers.
3 citations
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December 2019 in “Lupus” In this report, researchers describe a case of scalp discoid lupus erythematosus unresponsive to topical treatments, where hydroxychloroquine administered at 200 mg/day led to complete resolution of skin lesions in five months.
This study found significant correlations between scalp and nail involvement and laboratory findings in Korean patients with chronic cutaneous lupus erythematosus, highlighting their importance for diagnosis and management.
148 citations
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February 2005 in “Autoimmunity Reviews” This article discusses the distinct skin findings associated with lupus erythematosus, noting that some are specific to lupus while others are nonspecific and occur with various diseases; it reports no new results.
3 citations
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May 2024 in “Skin Appendage Disorders” This study observed that trichoscopy of long-lasting lesions in a chronic stage revealed specific features such as absence of follicular openings, cicatricial patches, and thick arborizing vessels.
14 citations
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May 2009 in “Journal of the American Academy of Dermatology” This case study describes a patient with discoid lupus erythematosus whose scalp lesions progressed despite treatment, with findings suggesting inclusion cysts and comedones as part of primary or secondary changes.
1 citations
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June 2014 in “Serbian Journal of Dermatology and Venereology” This case report describes a 22-year-old woman initially suspected of alopecia areata, whose scalp lesions were ultimately diagnosed as discoid lupus erythematosus after histopathological analysis.
74 citations
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March 2001 in “Seminars in Cutaneous Medicine and Surgery” This review summarizes the cutaneous manifestations of lupus erythematosus, noting both non-specific and disease-specific lesions, and highlights the role of skin biopsies and treatments available for cutaneous LE.
15 citations
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June 2020 in “Journal of the American Academy of Dermatology” Shiny white structures in trichoscopy can indicate long-standing discoid lupus erythematosus alopecia.
28 citations
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November 2017 in “Skin appendage disorders” This paper proposes a systematic approach to evaluating scalp itch using the SCALLP acronym and highlights the importance of classifying cases based on the presence of dermatological lesions and hair loss, but it reports no new clinical findings.