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This study found that epidermal melanocytes can regenerate hair follicles, whereas non-cutaneous or dermal melanocytes cannot, suggesting two distinct melanocyte lineages with potential implications for melanocyte-related diseases.

This article reviews the role of KLF4, a transcription factor, in various cellular processes and its dual function as a tumor suppressor or oncogene depending on the context, but presents no new experimental results.

This review highlights that the RNA modification N⁶-methyladenosine (m⁶A) plays a crucial role in regulating wound healing and tissue remodeling, with dysregulation contributing to complications in chronic wounds, such as diabetic ulcers and burn injuries, through mechanisms like impaired angiogenesis and increased oxidative stress.

In this study, beta-caryophyllene enhanced wound healing in female mice by improving re-epithelialization, cell proliferation, and cell migration, suggesting potential benefits of essential oil compounds in inflammation reduction.

This review suggests that induced pluripotent stem cells (iPSCs) hold promise for treating chronic wounds, but further work is needed to address safety, efficacy, and translation from preclinical models to real-world applications.

This research discusses how epithelial stem cells in the skin maintain normal homeostasis, contribute to wound repair, and highlights the importance of these processes, as defects can lead to skin diseases including cancers, but provides no new experimental results.

This protocol describes using two-photon laser-scanning microscopy to study hair regeneration in live mice, offering detailed imaging capabilities for observing hair follicle stem cell behavior and manipulating cellular populations.

This study found that using the OptoTrkA system to control TrkA activity with blue light enhanced proliferation, migration, and differentiation of hair-follicle-derived stem cells into neuronal and glial cells.

This study found that tdDPC-EVs significantly improved wound healing by enhancing angiogenesis through the KLF4/VEGFA axis, offering advantages over traditional DPC-EVs.

This review highlights that two-photon excitation microscopy is a valuable tool for visualizing live skin structures and immune responses at high resolution, though its clinical use is hindered by safety and cost issues.

T cells and bacteria in the gut and skin help maintain health and protect against disease.

In this review, researchers explored key mechanisms underlying androgenetic alopecia, revealing how hormonal, oxidative, inflammatory, and lipid dysregulation suppress hair growth pathways and suggesting new therapeutic targets such as DP2 antagonists and microbiome modulators.

This study demonstrates that SDF-1/CXCL12 and CXCR4 signaling play a crucial role in directing the migration and positioning of melanoblasts in mouse hair follicle formation.

This study found that Caspase-1, traditionally viewed as an inflammasome component, is secreted upon wounding and plays a novel role by triggering hair follicle stem cell migration into the epidermis, offering insights into epithelial hyperplasia mechanisms in inflammatory skin conditions.

This study observed that VEGF165 increases proliferation and migration but alters adhesion properties of cultured human hair follicle cells, indicating a potential role for VEGF/VEGFR-2 in hair follicle regulation beyond angiogenesis.

In this study on Drosophila embryos, researchers observed that the Slit/Robo signaling pathway is crucial for the collective migration and proper positioning of Posterior Signaling Center cells within the hematopoietic niche, highlighting its role in niche assembly and cellular organization.

This study proposed a new approach to combat leishmaniasis by targeting host proteins rather than the parasite itself, identifying eight existing drugs as potential treatments despite not having been previously tested on leishmaniasis.

This study identified common and previously unlisted adverse events associated with four anti-CGRP monoclonal antibodies for migraine prevention, highlighting a varied safety profile post-marketing.

This study found that stress-induced inactivation of the enzyme Dicer in melanocytes can cause premature hair greying by preventing proper melanocyte placement and melanin transfer in mice, suggesting the Dicer-miR92b-ItgaV pathway as an important link between stress and grey hair.

mIGF-1 in skin cells speeds up wound healing and hair growth in mice without harmful effects.

This study found that the absence of Ctip2 in epidermal keratinocytes led to impaired wound healing in mice, affecting cell migration, proliferation, and hair follicle stem cell maintenance.

This study found that increased intracellular expression of thymosin β4 is necessary and sufficient to induce PAI-1 gene expression in endothelial cells, potentially mediated through Ku80 as a novel receptor.

This study found that actively targeted AN2728-loaded nanocarriers reduced inflammation and improved skin condition in a mouse model of psoriasiform inflammation compared to free drug and non-targeted nanoparticles.

This study identified a comprehensive global landscape of stemness-related gene clusters in adipose-derived mesenchymal stem cells, revealing that stemness was highest in cells from young donors and lowest in those from elderly donors.

This review summarizes the mechanisms of mesenchymal stem cell-mediated wound healing and highlights engineering strategies that enhance therapeutic outcomes, but it reports no new clinical results.

This review explores the potential diagnostic and therapeutic applications of extracellular vesicles in treating various skin conditions but reports no new clinical study results.

This study found that Kangfuxin improved cell proliferation, migration, and wound healing in a mouse model of cutaneous injury through the activation of the STAT3 signaling pathway.

This review compiles evidence from 20 relevant studies and suggests that platelet-rich plasma-derived extracellular vesicles represent a promising therapeutic option in regenerative medicine, although the authors emphasize the need for standardized protocols due to inconsistencies across studies.

This study found that Plerixafor, a CXCR4 antagonist, promotes melanogenesis in melanocytes by increasing MITF and tyrosinase expression and enhancing melanocyte migration, and it effectively restores pigmentation in a mouse depigmentation model without toxicity, highlighting its potential for treating pigmentary disorders.

This study suggests that black ginseng concentrate protects human follicle dermal papilla cells against oxidative stress, potentially offering a natural approach to prevent cellular dysfunction linked to hair loss.