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Scientists have improved 3D models of human skin for research and medical uses, but still face challenges in perfectly replicating real skin.

Activating a protein called β-catenin in adult skin can make it behave like young skin, potentially helping with skin aging and hair loss.

The research suggests that a specific skin gene can be controlled by signals within and between cells and is wrongly activated in certain skin diseases.

Environmental cues can change the fate and function of epithelial cells, with potential for cell therapy.

Activating β-catenin in different skin stem cells causes various types of hair growth and skin tumors.

The research found that different types of fibroblasts are involved in wound healing and that some blood cells can turn into fat cells during this process.

KLF4 is important for maintaining stem cells and has potential in cancer treatment and wound healing.

Inflammation plays a key role in activating skin stem cells for hair growth and wound healing, but more research is needed to understand how it directs cell behavior.

Metformin, a diabetes drug, may also help fight cancer, but more research is needed to understand how.

New hair can grow from large wounds in mice, but less so as they age, involving reprogramming of skin cells and specific molecular pathways.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Estrogen is important for keeping adult mouse nipple skin healthy by controlling certain cell signals.

Smart biomaterials that guide tissue repair are key for future medical treatments.

Skin health and repair depend on the signals between skin stem cells and their surrounding cells.

Small molecule drugs show promise for advancing regenerative medicine but still face development challenges.

Dermal papilla cells can help regrow hair and are promising for hair loss treatments.

Dermal stem cells help regenerate hair follicles and heal skin wounds.

Histone modification is key in treating chronic inflammatory skin diseases.

Oxidative stress affects hair loss in men with androgenetic alopecia.

The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.

Special fiber materials boost the healing properties of certain stem cells.

Hair follicles are valuable for regenerative medicine and wound healing.

MSC-derived exosomes can help treat COVID-19, hair loss, skin aging, and arthritis.

Macrophages help heal nerves by aiding the maturation of Schwann cells and are important for nerve repair.

The document concludes that dermal papilla cells are key for hair growth and could be used in new hair loss treatments.

The gene Msx2 is crucial for hair follicle regeneration during wound healing.

Changing the environment around stem cells could help tissue repair, but it's hard to be precise and avoid side effects.

Changing how mesenchymal stromal cells are grown can improve their healing abilities.

Mesenchymal stem cells help improve wound healing by reducing inflammation and promoting skin cell growth and movement.

MicroRNAs are important for skin health and could be targets for new skin disorder treatments.