Lichen planopilaris and frontal fibrosing alopecia are likely the same disease with different clinical appearances.
Accurate diagnosis of cicatricial alopecias requires thorough scalp examination and multiple biopsy techniques.
Detailed history and physical examination are crucial for diagnosing hair loss.
51 citations,
January 2007 in “The journal of investigative dermatology/Journal of investigative dermatology” Scientists discovered a unique hair protein, KAP24.1, with a special structure, found only in the upper part of hair cuticles.
13 citations,
August 1991 in “The Journal of the American Osteopathic Association” 15 citations,
July 2014 in “The journal of investigative dermatology/Journal of investigative dermatology” iPSCs can help treat genetic skin disorders by creating healthy skin cells from a small biopsy.
5 citations,
October 2012 in “Veterinary Pathology” A Doberman Pinscher had a rare form of autoimmune disease causing hair loss and other severe symptoms.
A man wrongly believed he had parasites, showing that delusional infestation can affect men and is often linked with other psychiatric issues, but can be treated with antipsychotics.
51 citations,
August 2013 in “The Journal of experimental medicine/The journal of experimental medicine” Loss of a specific protein in skin cells causes symptoms similar to psoriasis.
35 citations,
June 2012 in “PloS one” Keratin 15 expression in skin cells is regulated by two mechanisms involving PKC/AP-1 and FOXM1.
25 citations,
December 2007 in “Developmental biology” Clim proteins are essential for maintaining healthy corneas and hair follicles.
16 citations,
September 2015 in “International Journal of Molecular Sciences” A specific gene variant causes severe skin issues and increases infection risk, requiring careful medical monitoring.
13 citations,
April 2022 in “Anais brasileiros de dermatologia/Anais Brasileiros de Dermatologia” The document concludes that more research is needed to find effective treatments for Lichen planopilaris and Frontal fibrosing alopecia.
10 citations,
December 2018 in “Internal Medicine” Myasthenia gravis can affect both motor and non-motor systems due to immune system issues.
4 citations,
September 2021 in “Dermatopathology” The conclusion is that Erosive Pustular Dermatosis of the Scalp is a rare condition best treated with strong topical steroids and sometimes systemic treatment.
March 2023 in “Nigerian Journal of Clinical Practice” The main difference in hair loss for lupus patients is smaller and fewer sebaceous glands.
January 2023 in “Skin appendage disorders” Hair loss is common in autoimmune diseases and can be an early sign of the condition, often requiring prompt treatment to prevent permanent damage.
December 2020 in “Journal of clinical and investigative dermatology” A man with syphilitic alopecia and neurosyphilis was successfully treated with penicillin, leading to symptom improvement and resolution of hair loss.
September 2013 in “Hair transplant forum international” The document says doctors should identify and treat Frontal fibrosing alopecia medically before considering surgery, as treatments often don't work well.
16 citations,
February 2018 in “Journal of The American Academy of Dermatology” Scalp biopsies from dermatomyositis patients show chronic hair loss without scarring, with mucin and blood vessel changes being very common.
25 citations,
July 1991 in “International Journal of Dermatology” Toxic Epidermal Necrolysis is a rare, serious skin condition that can affect anyone, is more common in women, and may be linked to genetics, with a 20% mortality rate mainly due to sepsis.
19 citations,
August 2012 in “Cell death and differentiation” Intu gene is crucial for hair follicle formation by helping keratinocytes differentiate through primary cilia.
17 citations,
July 1994 in “Journal of Dermatological Science” The cause of alopecia areata is likely a mix of genetics, immune system issues, and environmental factors, with more research needed to understand it fully.
June 2008 in “Springer eBooks” The document concludes that permanent hair loss conditions are complex, require early specific treatments, and "secondary permanent alopecias" might be a more accurate term than "secondary cicatricial alopecia."
18 citations,
September 2003 in “The journal of investigative dermatology/Journal of investigative dermatology” VDUP1 is found in skin and hair follicles, interacts with sciellin, and may help regulate skin cell differentiation.
3 citations,
April 2022 in “International Journal of Molecular Sciences” Scientists turned mouse skin cells into hair-inducing cells using chemicals, which could help treat hair loss.
70 citations,
April 2017 in “Lasers in surgery and medicine” Blue light promotes hair growth by interacting with specific receptors in hair follicles.
1 citations,
January 2018 in “Methods in molecular biology” The research found ways to activate melanocyte stem cells for potential treatment of skin depigmentation conditions.
January 2023 in “Open Life Sciences” VEGFR-2 activation is likely involved in hair follicle growth, survival, and development.
106 citations,
October 2016 in “Cell Stem Cell” PDGFA/AKT signaling is important for the growth and maintenance of certain skin fat cells.