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Orlistat helped reduce weight and testosterone in obese women with PCOS but did not significantly affect other androgens or cholesterol levels.

Postmenopausal hyperandrogenism, a condition with symptoms like increased hair growth and acne, is usually caused by PCOS but can also be due to other factors. It's diagnosed by checking testosterone levels and treated either by removing the adrenal tumor or through antiandrogen therapy.

Sex hormones like estrogen and testosterone may affect COVID-19 severity differently in men and women, potentially influencing prevention and treatment strategies.

Certain ESR1 gene variations may affect hormone levels and fat distribution in women with high male hormone levels.

Androgens are important for female fertility and could help in IVF treatment, but also play a role in causing PCOS.

Metformin is less effective in men with early-onset hair loss.

High androgen levels in postmenopausal women may suggest an ovarian tumor, and removing it can improve heart and metabolic health.

PCOS causes infertility mainly due to hormonal imbalances, insulin resistance, and chronic inflammation.

Finasteride, a hair loss drug, may cause long-term sexual side effects due to changes in hormone receptor levels.

High BMI worsens hair growth in women with PCOS.

Classical PCOS types A and B are most common and linked to higher health risks.

Non-hormonal treatments should be used first for sexual dysfunction in postmenopausal breast cancer patients on aromatase inhibitors, with hormones as a second option.

Understanding how DHT works is important for diagnosing and treating hormone-related disorders.

Oral estradiol works for many transgender women but needs personalized dosing and monitoring.

Girls with PCOS have higher levels of certain androgens, which are linked to excess hair growth, but these androgens don't help diagnose PCOS.

The guideline provides healthcare professionals in South Africa with instructions for comprehensive, multidisciplinary gender-affirming care, including HIV prevention and treatment for transgender and gender diverse individuals.

Dutasteride, usually used for prostate issues and hair loss, could potentially treat Amyotrophic Lateral Sclerosis (ALS) due to its neuroprotective, antioxidant, and anti-inflammatory properties, but more testing is needed.

Many women with polycystic ovary syndrome have normal blood sugar, but some may have higher blood sugar levels or diabetes, especially if they are older, overweight, and have certain hormone levels.

Statins may help treat PCOS by lowering androgen levels and improving cholesterol.

Men and women react differently to opioids, with hormones potentially influencing these differences.

PCOS management includes lifestyle changes and medications, with ongoing research into repurposed drugs for better treatment options.

Acne can't be cured but can be managed with treatments like benzoyl peroxide and diet changes; it's costly and can lead to scarring and mental health issues.

Autism's genetics are linked with early age of puberty and less hair loss, but not with hormone levels or polycystic ovary syndrome.

Spironolactone plus finasteride reduces hirsutism more effectively.

Male hormones, or androgens, affect women's health in areas like mood and bone density, and hormone replacement therapy using antiandrogenic progestogens can improve mood disorders and alertness in menopausal women.

The document concludes that combination therapy is most effective for treating excessive hair growth in women with idiopathic hirsutism, and more research is needed to understand the condition.

Clinical signs of excess male hormones and actual hormone levels in the blood do not always match in women with polycystic ovary syndrome.

Testing basal 17-HP levels is a good way to screen for nonclassic adrenal hyperplasia in women with high androgen levels.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Metformin has limited effectiveness for improving PCOS symptoms and lacks clear benefits, needing more research to confirm its efficacy.