271 citations
,
September 2008 in “Nutrition reviews” This study identified new dietary ligands for the human vitamin D receptor, including curcumin and gamma-tocotrienol, which may influence its biological functions.
260 citations
,
December 2012 in “Cold Spring Harbor Perspectives in Biology” This review discusses the significant role of Wnt signaling in skin development, homeostasis, and disease, highlighting recent advances in understanding its diverse functions, but reports no new experimental results.
199 citations
,
April 2010 in “Nature” A gene called APCDD1, which controls hair growth, is found to be faulty in a type of hair loss called hereditary hypotrichosis simplex.
144 citations
,
March 2013 in “Circulation Research” This study reports that mutations in the SUR2 gene are linked to Cantu syndrome, highlighting the role of KATP channels in cardiovascular health and potential new therapies.
73 citations
,
June 2001 in “Endocrinology” In this study, researchers found that disrupting the PRL gene in mice led to earlier hair molting, especially in females, suggesting that PRL inhibits murine hair cycle events.
40 citations
,
November 2009 in “Experimental Dermatology” This review discusses the role of the mineralocorticoid receptor in skin biology, highlighting its potential involvement in keratinocyte and hair physiology, and proposes it may affect the side effects of glucocorticoid use.
34 citations
,
September 2020 in “BMC Endocrine Disorders” This review highlights that while dexamethasone may reduce mortality in severe COVID-19, no other drugs have proven effectiveness for treatment, emphasizing the need for clinical trials of existing medications.
31 citations
,
January 2011 in “Dermato-endocrinology” This review updates the protective effects and molecular mechanisms of melatonin against ultraviolet-induced damage in human skin, reporting no new clinical findings.
30 citations
,
April 2021 in “The Journal of Sexual Medicine” This guideline provides recommendations for prescribing systemic testosterone to women with hypoactive sexual desire disorder, emphasizing safe dosing, monitoring, and the need for informed consent despite regulatory challenges.
25 citations
,
July 2021 in “Journal of Medical Virology” This review focuses on the various skin symptoms associated with COVID-19 but reports no new clinical findings.
25 citations
,
March 2009 in “Dermatologic Surgery” This abstract contains no specific study findings, results, or conclusions to summarize.
23 citations
,
December 2006 in “Evaluation and Program Planning” This article presents a model for evaluating public R&D that emphasizes measuring capacity-based metrics over traditional outcome-based metrics, using the concept of a Knowledge Value Collective.
20 citations
,
September 2006 in “The Veterinary clinics of North America. Small animal practice/Veterinary clinics of North America. Small animal practice” This article reviews new drug therapies for endocrine disorders, discussing specific treatments such as trilostane for hyperadrenocorticism and various insulins for diabetes mellitus, but it reports no new clinical findings.
19 citations
,
September 2010 in “The American journal of pathology” This study demonstrated that elevated glucocorticoid levels in transgenic mice led to pancreatic exocrine cells transforming into hepatocyte-like cells, resulting in pancreatic dysfunction.
18 citations
,
December 2020 in “Frontiers in cell and developmental biology” This study found that extracellular vesicles from low-passage dermal papilla cells may activate hair growth by delivering miR-140-5p, which downregulates BMP2 signaling, suggesting potential therapeutic targets for alopecia.
17 citations
,
November 2002 in “Australasian Journal of Dermatology” This case report describes a 24-year-old woman with androgenetic alopecia who developed sensitivity to topical minoxidil and later to saw palmetto after using a minoxidil and retinoic acid preparation.
14 citations
,
June 2001 in “Endocrinology” This study found that disrupting the PRL gene in mice alters the timing of hair cycling events, causing earlier molts and changes in hair characteristics, particularly affecting female mice more significantly.
9 citations
,
March 2018 in “Actas Dermo-Sifiliográficas” This study found that the Spanish version of the Hair Specific Skindex 29 (HSS29) is a reliable and valid tool for assessing the quality of life impact of female androgenetic alopecia.
4 citations
,
January 2014 in “BioMed Research International” This special issue reviews advancements in engineering cell microenvironments for tissue engineering, highlighting various studies on interventions like silk fibroin and platelet-rich plasma, but presents no new empirical findings.
4 citations
,
January 1987 in “Journal of The American Academy of Dermatology” A man with both skin lesions and lung cancer improved quickly with chemotherapy, suggesting the skin condition might be a reaction to immune system injury.
1 citations
,
June 2023 in “Ethnobotany research and applications” This review examined the medicinal properties of the Ziziphus plant species, highlighting their traditional use in treating various conditions and their bioactive compounds with potential anticancer, antimicrobial, and anti-diabetic effects. The authors concluded that Ziziphus species, particularly jujube, have promising pharmacological activities warranting further investigation.
March 2026 in “Folia Histochemica et Cytobiologica” This review highlights LTBP1 as a critical integrator in disease processes, showing its dual role in cancer progression and suppression, its pathological influence in fibrosis, and its contribution to various disorders, suggesting its potential as a biomarker and therapeutic target.
March 2026 in “Calcified Tissue International” This review discusses the complex role of the EDA pathway in vertebrate skeletal development, emphasizing its interaction with other morphogenic pathways to influence skeletal diversity, but reports no new experimental results.
This source provides medical information intended solely for licensed professionals and emphasizes that it is not a substitute for medical advice, diagnosis, or treatment decisions, which remain the responsibility of treating physicians.
January 2024 in “Medical Research Archives” This source highlights the emerging field of psychodermatology, which examines the interplay between psychological factors and skin disorders, noting a historical lack of attention due to inadequate professional training and emphasizing the need for integrated care involving dermatologists, psychiatrists, and psychologists.
This case report highlights a rare instance of minoxidil-induced pleuro-pericardial effusion with tamponade in a patient with end-stage renal disease on hemodialysis, which improved following pericardiocentesis and discontinuation of the drug.
October 2023 in “The Egyptian Journal of Hospital Medicine ” This review discusses the potential use of prostate specific antigen as a diagnostic marker for hyperandrogenism in polycystic ovary syndrome but reports no new clinical results and calls for further research.
August 2020 in “Bioscience Biotechnology Research Communications” This study found that using topical anesthetic was more effective than a vibrating device in reducing discomfort from dental injections.
July 1994 in “Annals of Pharmacotherapy” Cromolyn sodium's effectiveness for treating asthma in children under 2 is unclear, possibly more beneficial for older children, and further research is needed.
This source provides a comprehensive guide for general practitioners to enhance their skills in diagnosing and managing both common and clinically significant dermatological disorders, serving as a key reference in everyday medical practice.