research Intracrine Testosterone Activation in Human Pancreatic Beta-Cells Stimulates Insulin Secretion
Testosterone helps human pancreatic cells increase insulin release.
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research Recent Advances in Drug Design and Drug Discovery for Androgen-Dependent Diseases
New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.
research Finasteride Has Regionally Different Effects on Brain Oxidative Stress and Acetylcholinesterase Activity in Acute Thioacetamide-Induced Hepatic Encephalopathy in Rats
Finasteride affects brain stress and enzyme activity differently in various regions, possibly helping with liver-related brain issues.
research Improving Selective Androgen Receptor Modulator Discovery and Preclinical Evaluation
We need better ways to test and understand SARMs to make safer and more effective treatments.
research Separation of Finasteride and Analogues
Finasteride and analogues separated using LC-MS-MS technique.
research Exclusive Androgenic Effect of Dehydroepiandrosterone in Sebaceous Glands of Rat Skin
DHEA acts like a male hormone on rat skin glands and doesn't turn into female hormones there.
research Endocrine Treatment of Benign Prostatic Hypertrophy: Current Concepts
New hormonal treatments for enlarged prostate show promise for safer, effective non-surgical options.
research Androgenic Effect of Testosterone and Its Metabolites in Relation to Their Biotransformation in the Skin
Testosterone and some of its forms can strongly stimulate oil gland growth in skin.
research The Effect of Minocycline on the Metabolism of Androgens by Human Oral Periosteal Fibroblasts and Its Inhibition by Finasteride
Minocycline may cause hair loss by increasing DHT levels, but finasteride can help counteract this effect.
research Hirsutism
Most women with excessive hair growth have PCOS; treatment varies and focuses on preventing new hair, with electrolysis as the only permanent removal method.
research Serum AMH Levels in the Differential Diagnosis of Hyperandrogenemic Conditions
Blood AMH levels are higher in women with PCOS than in those with other similar conditions.
research Ovarian Hilus-Cell Hyperplasia and High Serum Testosterone in a Patient With Postmenopausal Virilization
A woman's male-like symptoms and high testosterone were due to ovarian hilus-cell hyperplasia, which improved after surgery.
research A Patient With Combined Polycystic Ovary Syndrome And Autoimmune Polyglandular Syndrome Type 2
A woman was the first known case to have both polycystic ovary syndrome and autoimmune polyglandular syndrome type 2, suggesting a need to check for both conditions in similar patients.
research New Treatments of Hyperandrogenism and Hirsutism
Hirsutism causes significant psychological distress in women.
research The Administration of Flumethasone by Three Different Routes, Its Measurement in the Plasma, and Some Effects on Wool Growth in Merino Wethers
Flumethasone causes wool shedding in Merino wethers, with recovery in about 60 days.
research Sustained Release of Inhibitor from Bionic Scaffolds for Wound Healing and Functional Regeneration
Researchers developed a scaffold that releases a healing drug over time, improving wound healing and skin regeneration.
research The Differences Between Aromatizable And Non-Aromatizable Androgens In Relation To Body Composition And Metabolic Syndrome Risk Factors In Men
Testosterone and dihydrotestosterone have similar effects on body composition and metabolic health in men.
research Proscar (Finasteride) Inhibits 5α-Reductase Activity in the Ovaries and Testes of Lytechinus Variegatus Lamarck (Echinodermata: Echinoidea)
Proscar (finasteride) blocks 5α-reductase in sea urchin ovaries and testes, suggesting potential treatment for androgen-related conditions.
research Effects of Flutamide, a Pure Antiandrogen, on Endocrine Parameters in the Adult Female Rat
Flutamide, an antiandrogen, has minimal impact on female rat endocrine systems and does not significantly change their reproductive cycles.
research Giant Cells in Male Pattern Alopecia: A Histologic Marker and Pathogenetic Clue
Giant cells found in some male pattern baldness cases may help diagnose it and suggest hair is mistakenly seen as foreign by the body.
research Inhibition of 5α-Reductase Alters Pregnane Metabolism in the Late Pregnant Mare
Inhibiting 5α-reductase increases progesterone levels in late pregnant mares.
research Circulating and Intraprostatic Sex Steroid Hormonal Profiles in Relation to Male Pattern Baldness and Chest Hair Density Among Men Diagnosed with Localized Prostate Cancers
Baldness in men with prostate cancer is linked to higher levels of certain sex hormones, but chest hair density is not.
research The Effect of Simvastatin on Plasma Steroid Hormone Levels in Metformin-Treated Women with Non-Classic Congenital Adrenal Hyperplasia
Simvastatin may help manage symptoms in women with non-classic congenital adrenal hyperplasia by lowering cholesterol and certain hormone levels.
research Discrimination and Proper Use of Polygoni Multiflori Radix, Cynanchi Wilfordii Radix, and Cynanchi Auriculati Radix in Korea: A Descriptive Review
The review suggests renaming two herbs to avoid confusion and recommends more research for safe use.
research Androgen Effects in Mammals
Testosterone is crucial for development, growth, and various body functions in mammals.
research Obesity and Female Androgenic Alopecia: A Cause and an Effect?
Obesity may contribute to female hair loss by increasing male hormone levels that affect hair follicles.
research Polycystic Ovarian Syndrome and Associated Hirsutism in Adolescents
Early diagnosis and treatment of PCOS in teenagers can help prevent more severe adult PCOS.
research Prenatal Androgenization of Ewes as a Model of Hirsutism in Polycystic Ovary Syndrome
Prenatally androgenized ewes can model increased hair diameter in women with PCOS.
research Hyperadrenocorticism in Ferrets
Hyperadrenocorticism in ferrets is linked to neutering and indoor housing, and is best treated with surgery and a deslorelin implant.
![Discovery of 7-Methoxy-6-[4-(4-Methyl-1,3-Thiazol-2-yl)-1H-Imidazol-5-yl]-1,3-Benzothiazole (TASP0382088): A Potent and Selective Transforming Growth Factor-β Type I Receptor Inhibitor as a Topical Drug for Alopecia](/images/research/9620bd26-3366-4f2a-bcac-f511697bbc41/small/35997.jpg)
research Discovery of 7-Methoxy-6-[4-(4-Methyl-1,3-Thiazol-2-yl)-1H-Imidazol-5-yl]-1,3-Benzothiazole (TASP0382088): A Potent and Selective Transforming Growth Factor-β Type I Receptor Inhibitor as a Topical Drug for Alopecia
A new compound shows promise as a topical treatment for hair loss.