45 citations,
September 1998 in “Journal of Investigative Dermatology” The enzyme 17β-HSD type 2 mainly performs oxidation in human sebaceous glands, which may help protect against acne.
38 citations,
June 2018 in “Archives of Toxicology” Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.
34 citations,
April 2014 in “Psychopharmacology” Stress and alcohol affect brain chemicals differently in rats, mice, and humans, influenced by genetic differences.
20 citations,
June 2007 in “Recent Patents on Endocrine, Metabolic & Immune Drug Discovery” Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.
18 citations,
October 2017 in “Drug Design Development and Therapy” DA-9401 helps protect rat testis from finasteride damage.
18 citations,
January 2002 in “Chemical & pharmaceutical bulletin/Chemical and pharmaceutical bulletin” New pregnane derivatives were more effective than finasteride at inhibiting a key enzyme for male pattern baldness.
17 citations,
April 2015 in “Tropical Journal of Pharmaceutical Research” Asiasari Radix et Rhizoma is safe and has potential for new drug development due to its therapeutic properties.
17 citations,
February 2009 in “Journal of Ethnopharmacology” Asiasari radix extract may relieve certain types of pain by affecting GABA and NMDA receptors.
17 citations,
November 2000 in “Journal of the American Pharmaceutical Association” The document concludes that low-dose oral contraceptives and hormonal therapies can manage perimenopause symptoms and reduce some health risks, but lifestyle changes and disease screening are also important.
16 citations,
September 2008 in “Dermatologic Therapy” CAH is a genetic disorder affecting cortisol production and causing hormonal imbalances, with treatment and diagnosis varying by form and symptoms.
14 citations,
January 2018 in “Advances in Clinical Chemistry” The document concludes that hormonal biomarkers are key for diagnosing hyperandrogenemia in women and hypogonadism in men.
13 citations,
January 2021 in “RSC chemical biology” Wnt activation shows promise for regenerative medicine but requires selective targeting to minimize risks like cancer.
12 citations,
February 2012 in “New England journal of medicine/The New England journal of medicine” A 72-year-old man had severe fatigue, weight loss, and frequent loose stools.
11 citations,
February 2021 in “Trends in Food Science and Technology” Impatiens plants have health-promoting compounds and are used for natural food coloring, but more research is needed to understand their full benefits.
7 citations,
January 2018 in “Reproduction” Inhibiting 5α-reductase increases progesterone levels in late pregnant mares.
7 citations,
January 2003 in “Elsevier eBooks” Testosterone is crucial for development, growth, and various body functions in mammals.
5 citations,
August 2018 in “Sexual Medicine Reviews” 5α-Reductase inhibitors do not consistently increase testosterone levels in the blood.
3 citations,
January 2016 in “Elsevier eBooks” Steroid hormones are crucial for body functions and have various medical uses, but their misuse can lead to dependence.
3 citations,
December 2000 in “International Journal of Cosmetic Science” The study created a new method to test drugs that affect hormone processing in skin.
2 citations,
December 1983 in “Outlook on Agriculture” Plant hormones have potential in agriculture to increase food production but require more research for effective use.
1 citations,
January 2019 in “Elsevier eBooks” Neuroactive steroids may affect the risk and treatment of alcohol use disorders.
December 2023 in “Frontiers in endocrinology” Excess androgens may cause PCOS, not just be a symptom.
March 2023 in “Journal of pharmacognosy and phytochemistry” Unripe fruits of three banana species have many health-boosting compounds useful for medicine.
January 2023 in “Zdravstvena zaštita” Aging-related hormone changes affect voice quality, especially during puberty, menstruation, pregnancy, and menopause.
November 2016 in “Elsevier eBooks” Genetic mutations can affect female sexual development, requiring personalized medical care.
20 citations,
June 2022 in “Molecules” Thiazole, a sulfur and nitrogen chemical, is useful in creating potential drugs for conditions like seizures, cancer, bacterial infections, tuberculosis, inflammation, malaria, viruses, Alzheimer's, diabetes, and A1-receptor issues.
11 citations,
November 2009 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” Bolandiol, a synthetic steroid, builds muscle and bone without greatly affecting sex glands, and works differently from other hormones.
56 citations,
January 2008 in “Molecular and cellular endocrinology” Two enzymes regulate androgen receptor activity, affecting treatments for androgen insufficiency and benign prostatic hyperplasia.
14 citations,
May 2016 in “Therapeutic advances in urology” Taking tadalafil and finasteride together is safe and effective for treating urinary symptoms and erectile dysfunction in men with enlarged prostates.
25 citations,
January 1999 in “Journal of cutaneous laser therapy” Diode laser effectively treats pseudofolliculitis barbae.