66 citations,
April 2017 in “International Journal of Andrology” Men taking 5α-reductase inhibitors for enlarged prostate have a higher chance of experiencing reduced sexual desire and erectile dysfunction.
65 citations,
January 2011 in “Frontiers in Endocrinology” Neurosteroids show promise for treating epilepsy and more research is needed.
58 citations,
April 2017 in “The Journal of Steroid Biochemistry and Molecular Biology” Post-finasteride patients show changed neuroactive steroid levels, possibly causing erectile dysfunction and depression.
58 citations,
September 2012 in “Dermatologic Clinics” Male pattern hair loss caused by follicular miniaturization; early diagnosis and treatment can reduce psychological burden.
50 citations,
October 2014 in “International Journal of Clinical Pharmacology and Therapeutics” New finasteride solution effectively reduces baldness-causing hormone, potentially with fewer side effects.
43 citations,
July 2018 in “Journal of The European Academy of Dermatology and Venereology” Finasteride and minoxidil mix works better for hair growth than minoxidil alone, with similar safety.
40 citations,
November 2020 in “JAMA Dermatology” Finasteride may cause suicidal thoughts and mental side effects, especially in young people with hair loss.
39 citations,
June 2019 in “Toxins” Bee venom might be a good alternative treatment for various skin conditions because it has many healing properties.
34 citations,
October 2018 in “Journal of The American Academy of Dermatology” Hormone treatments can help with women's skin and hair disorders, but they need careful monitoring and more research.
34 citations,
September 2013 in “Urology” Long-term use of a certain medication can worsen erectile function in aged rats by damaging penile muscle cells.
33 citations,
April 2015 in “Current Opinion in Endocrinology, Diabetes and Obesity” 5α reductase inhibitors treat hair loss but may cause sexual side effects and risks.
32 citations,
June 2017 in “Journal of Pharmaceutical Sciences” Chitosan-coated nanoparticles improve skin delivery of hair loss treatments with fewer side effects.
31 citations,
January 2017 in “Advances in Experimental Medicine and Biology” Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.
31 citations,
February 2016 in “American Journal of Men's Health” Finasteride can cause serious emotional side effects; doctors should check patients' mental health history before prescribing.
31 citations,
November 2014 in “Investigative Ophthalmology & Visual Science” A natural steroid in the body may protect against eye damage in glaucoma.
30 citations,
September 2016 in “BMJ” Taking 5-α reductase inhibitors for prostate enlargement or hair loss does not significantly raise the risk of erectile dysfunction.
30 citations,
April 1997 in “European journal of endocrinology” The document concludes that managing hirsutism involves identifying the cause, using a scoring system for severity, combining cosmetic and medical treatments, encouraging weight loss, and providing psychological support, while noting the need for more research on drug treatments.
28 citations,
October 1998 in “Baillière's clinical endocrinology and metabolism” Testosterone replacement may help post-menopausal women with androgen insufficiency, but more research is needed on its benefits and risks.
25 citations,
May 2012 in “The Journal of Sexual Medicine” Finasteride reduces corpus cavernosum weight but doesn't affect erectile response in rats.
23 citations,
October 2018 in “Expert Opinion on Drug Safety” Consider benefits and risks of new alopecia treatments for safety.
20 citations,
October 2018 in “Clinical Drug Investigation” Dutasteride does not impair mental function in elderly men with enlarged prostate.
20 citations,
June 2017 in “Hormone Molecular Biology and Clinical Investigation” Long-term use of dutasteride for enlarged prostate may worsen blood sugar, cholesterol, and erectile dysfunction.
20 citations,
June 2015 in “Hormone Molecular Biology and Clinical Investigation” Finasteride worsens erectile dysfunction and lowers testosterone in men with enlarged prostates, unlike tamsulosin.
20 citations,
April 2012 in “Fertility and Sterility” Finasteride causes lasting fertility decrease in rats.
19 citations,
March 2019 in “Behavioural Brain Research” Finasteride use can cause depression-like behavior in male rats.
18 citations,
May 2015 in “Australasian Journal of Dermatology” Serenoa repens extract in topical products improves hair growth and appearance in male pattern baldness with mild side-effects.
17 citations,
November 2014 in “American Journal of Physiology-gastrointestinal and Liver Physiology” Finasteride helps brain function in rats with liver-related brain issues.
16 citations,
December 2014 in “International Journal of Biological Markers” Longer CAG and GGN repeats increase alopecia risk, but no significant link to post-finasteride syndrome found.
15 citations,
July 2016 in “Urologic Clinics of North America” Finasteride and dutasteride are effective for long-term treatment of enlarged prostates but have sexual side effects and a risk of high-grade prostate cancer.
15 citations,
January 2016 in “Biological & Pharmaceutical Bulletin” Bee venom helps hair grow and may work better than some common treatments.