May 2023 in “Zenodo (CERN European Organization for Nuclear Research)” In this review, researchers synthesized current knowledge on Eclipta alba (Bhringaraja) from traditional Ayurvedic texts and scientific literature, reporting its wide range of pharmacological properties, including hepatoprotective, antioxidant, antimicrobial, and anticancer effects, attributed to its chemical compounds like wedelolactone.
May 2023 in “GSC Advanced Research and Reviews” This review highlights the diverse pharmacological properties of Eclipta alba, often used traditionally in Asian medicine, detailing its hepatoprotective, hair growth promoting, antidiabetic, and other therapeutic activities linked to its chemical compounds such as wedelolactone.
June 2025 in “Universities Journal of Phytochemistry and Ayurvedic Heights” This study evaluated the wedelolactone content and antimicrobial activity of Eclipta alba and Wedelia chinensis extracts, finding a potential relationship between the concentration of wedelolactone and their in vitro antimicrobial effects against several pathogenic bacteria and yeast.
83 citations
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October 2012 in “International Journal of Oncology” In this in vitro study, wedelolactone induced selective apoptosis in prostate cancer cells by inhibiting 5-Lox activity, suggesting it may have potential as a treatment for prostate cancer.
January 2000 in “Time to knit” This article describes the extraction and characterization method for wedelolactone from Eclipta alba but presents no new clinical results.
64 citations
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June 2020 in “PLoS ONE” This study found that red light exposure significantly enhanced the growth, phytochemical content, and therapeutic potential of Eclipta alba callus cultures compared to other multispectral light exposures.
In this study, researchers identified an elite germplasm of the medicinal plant Eclipta alba, known for its liver disease benefits, with higher growth, yield, and wedelolactone content, suitable for large-scale cultivation to reduce strain on wild populations.
This review discusses the medicinal uses and phytochemical composition of Eclipta alba and reports no new clinical findings; the authors suggest its potential therapeutic significance due to complex interactions of its constituents.
49 citations
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October 2014 in “International Scholarly Research Notices” This review explores the medicinal properties of Eclipta alba and its phytoconstituents and reports their potential for developing new drugs, but presents no new research results.
August 2023 in “Apple Academic Press eBooks” This review highlights that various parts of Eclipta prostrata contain compounds with potential antioxidant, anti-inflammatory, hepatoprotective, and hair growth-promoting effects, among other activities.
8 citations
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January 2014 in “BioMed Research International” This study reported that among three plant extracts tested for hair growth on nude mice, Eclipta alba significantly increased hair density and length, unlike Asiasari radix and Panax ginseng.
6 citations
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October 2023 in “Pharmaceuticals” This study found that the extract of Eclipta prostrata L. demonstrated high antioxidant and anti-acetylcholinesterase activities, moderate inhibition of enzymes linked to diabetes, and favorable ADMET properties, suggesting potential cognitive and diabetes management benefits.
November 2025 in “Essential Chem” In this study, Eclipta alba extract showed potential for hair regrowth by increasing the proliferative activity of human dermal papilla cells by 45% in vitro, with evidence suggesting activation of the Wnt signaling pathway.
10 citations
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January 2009 in “Scientific Electronic Library Online (São Paulo Research Foundation, Latin American and Caribbean Center on Health Sciences Information, Conselho Nacional de Desenvolvimento Científico e Tecnológico)” This study found that Eclipta alba extracts exhibit significant antimicrobial activity against various human pathogens, including antibiotic-resistant strains, suggesting potential use in treating infectious diseases.
50 citations
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May 2011 in “Journal of Ethnopharmacology” In this cell study, Eclipta alba extract inhibited cancer cell proliferation and induced apoptosis, showing potential antiproliferative and anti-metastasis effects on liver and related cancer cell lines.
July 2025 in “International Journal of Allied Medical Sciences and Clinical Research” This review compiles current knowledge of Eclipta prostrata's botanical details, ethnomedical uses, phytochemical components, and various pharmacological activities, emphasizing its potential for modern pharmaceutical formulations based on its anti-inflammatory, antioxidant, anticancer, and other therapeutic properties.
January 2024 in “International Journal For Multidisciplinary Research” This review examines existing studies on Eclipta prostrata, highlighting its diverse bioactive compounds and potential therapeutic benefits in traditional medicine, and underscores the need for further research to fully develop its medicinal promise.
August 2025 in “International Journal of Research Publication and Reviews” In this review, researchers compiled and analyzed existing data on the traditional uses, chemical components, and biological activities of the plant Eclipta alba, commonly utilized in Ayurvedic and Unani medicine for treating various ailments including liver disorders, hair loss, and skin conditions.
January 2025 in “International Journal for Research in Applied Science and Engineering Technology” This review discusses the traditional medicinal uses of Eclipta alba (Bhringraj) in various systems, highlighting its phytochemical constituents and diverse biological activities, including potential benefits for hair growth, liver health, and immune function.
May 2020 in “International Journal of Engineering Applied Sciences and Technology” This study explored the antimicrobial potential of natural bioactive materials such as Citrus lemon, Garlic, Baeckea frutescens, Neem, and Eclipta Alba, highlighting their eco-friendly and non-toxic properties for combating harmful bacteria.
35 citations
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June 2017 in “Pharmacognosy Journal” This study found that alkaloids isolated from Eclipta alba leaves showed increasing antimicrobial activity with higher concentrations, particularly against S. aureus and E. coli, suggesting potential for developing antimicrobial agents.
33 citations
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December 2023 in “Cell Death Discovery” This study found that cepharanthine can inhibit gastric cancer cell activity by inducing oxidative stress and altering energy metabolism, suggesting its potential for gastric cancer treatment.
24 citations
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December 2014 in “International Journal of Molecular Medicine” In this study, researchers found that petroleum ether extract of Eclipta alba significantly stimulated follicular keratinocyte proliferation and reduced TGF-β1 expression in nude mice, suggesting potential use for certain types of alopecia.
4 citations
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May 2023 in “Research Square (Research Square)” This study found that cephalanthine inhibited the growth of gastric cancer cells in vitro and in vivo by inducing oxidative stress and altering energy metabolism, suggesting its potential as a treatment for gastric cancer.
April 2026 in “Frontiers in Pharmacology” This review systematically evaluates Erzhi Pill's formulation, therapeutic potential, and challenges, exploring its traditional applications and modern prospects for developing integrated quality control and precise medical strategies.
In this review, researchers evaluated 111 studies on the biological activities and phytochemical components of the plant Tridax procumbens, emphasizing its ethnobotanical potential and the need for more research to understand its therapeutic benefits, especially in its native tropical regions.
January 2025 in “International Journal of Pharmacognosy and Life Science” In this review, researchers highlighted the potential benefits of using herbal remedies, such as Aloe vera, Bhringraj, Neem, Tea tree oil, Amla, and Hibiscus, for treating various hair problems like dandruff, scalp infections, and premature greying, suggesting natural alternatives to traditional hair treatments.
February 2024 in “Oriental Journal of Chemistry/Oriental journal of chemistry” This review reports various ethnomedicinal uses, phytochemical components, and potential pharmacological effects of Eclipta alba, highlighting benefits like wound healing and neuroprotection, though it underscores the need for further mechanism-based studies and clinical trials.
June 2023 in “International journal of research in ayurveda and pharmacy” This study explores how Dhatryadi rasayana, a polyherbal formulation with antioxidant properties, may help prevent and treat premature hair greying by addressing factors such as oxidative stress, nutritional deficiencies, and hormone imbalances, potentially through rasayana therapy.
121 citations
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May 2009 in “Journal of Ethnopharmacology” This study found that the methanol extract of Eclipta alba showed dose-dependent hair growth promoting activity in pigmented C57/BL6 mice by influencing the transition from the telogen to anagen phase.