14 citations
,
December 2003 in “Medical Hypotheses” This paper proposes a new hypothesis that androgenic hair loss may be caused by changes in scalp vasculature due to androgen effects, but reports no new experimental results.
9 citations
,
February 2018 in “Journal of Pharmaceutical and Biomedical Analysis” This study validated a highly selective and fast LC–MS/MS method for accurately measuring levels of tadalafil and finasteride in human plasma, adhering to international bioanalytical guidelines.
9 citations
,
October 1988 in “Clinics in Dermatology” This paper discusses androgenetic alopecia, its causes, synonyms, and patterns, but reports no new findings or clinical results.
8 citations
,
October 2008 in “Medical hypotheses” This article introduces a new theory on male pattern baldness, attributing it to scalp pressure affecting hair follicles, and suggests it could revolutionize understanding and treatment; no clinical results are presented.
5 citations
,
February 2013 in “Journal of Liquid Chromatography & Related Technologies” This study developed and validated a micellar electrokinetic chromatography method to determine finasteride stability, finding that the drug degrades under acidic, basic, and oxidative stress conditions.
4 citations
,
March 2019 in “Acta Chromatographica” This study developed two sensitive chromatographic methods for determining finasteride and tamsulosin hydrochloride in pharmaceutical forms, validated against International Conference on Harmonisation guidelines.
4 citations
,
November 1996 in “European journal of endocrinology” This study found that spironolactone therapy may reduce hair width in prepubertal girls with simple hypertrichosis, though its long-term efficacy and safety remain uncertain.
3 citations
,
January 2011 This study developed a precise and reliable UV spectrophotometric method for determining finasteride concentration in bulk and tablets, demonstrating strong linearity and accuracy.
1 citations
,
January 2020 in “Skin appendage disorders” Finasteride may help treat frontal fibrosing alopecia, but more research is needed.
1 citations
,
January 2017 in “Asian Journal of Chemistry” New method effectively analyzes finasteride and its stability.
1 citations
,
March 1992 in “Postgraduate Medicine” This article reviews causes, differentiation, and treatment of thinning hair in women, with no new clinical results reported.
March 2024 in “Cleveland Clinic journal of medicine” This review details contemporary medical management options for benign prostatic hyperplasia, highlighting the expanding role of phosphodiesterase-5 inhibitors and beta-3 agonists, but reports no new clinical findings.
January 2019 in “The Pharma Innovation Journal” This study found that optimal antioxidant properties of a cream-mask, as indicated by extended Paramecium caudatum motor activity in a toxic environment, were achieved with 10% Sophora japonica tincture and 5% Serenoa repens dry extract.
21 citations
,
October 2008 in “Indian Journal of Plastic Surgery” This article discusses recent advancements in hair transplantation techniques that combine art and science for more natural results, but reports no new clinical findings.
May 2013 in “Trends in Urology & Men's Health” This article reviews non‐surgical treatments and surgical techniques for male‐pattern hair loss and does not present new findings.
72 citations
,
January 2011 in “Current Pharmaceutical Design” This review discusses the potential role of steroid 5α-reductase inhibitors in treating neuropsychiatric disorders related to dopaminergic hyperreactivity but reports no new clinical results.
46 citations
,
September 2011 in “Journal of Endocrinology” This study suggests that 5α-reduced glucocorticoids may have anti-inflammatory potential and could serve as biomarkers for liver inflammation in metabolic disease, with implications for drug development.
28 citations
,
December 2003 in “Medical Hypotheses” This paper suggests that ketoconazole 2% shampoo may enhance finasteride's effectiveness in treating androgenetic alopecia by more completely inhibiting the dihydrotestosterone pathway.
25 citations
,
September 1998 in “The Journal of Steroid Biochemistry and Molecular Biology” This study concludes that rhesus macaques are a suitable model for testing the pharmacological properties of finasteride and other 5aR inhibitors, due to their biochemical similarity to humans.
20 citations
,
October 2018 in “Clinical Drug Investigation” This study observed that men receiving dutasteride for benign prostatic hyperplasia did not show significant differences in neuropsychological assessments compared to a control group not on dutasteride.
20 citations
,
August 2005 in “Journal of Cutaneous Pathology” This study found that in male androgenic alopecia, the androgen receptor coactivator ARA70/ELE1 exhibits differential expression patterns, suggesting its involvement in the condition.
11 citations
,
January 2017 in “Journal of Endocrinology/Journal of endocrinology” This study observed that female mice with disrupted 5α-reductase 1 showed increased insulin resistance and hepatic steatosis, suggesting altered glucocorticoid metabolism contributes to metabolic disorders.
7 citations
,
January 1994 in “Annual Reports in Medicinal Chemistry” This review discusses hormonal manipulation for conditions like prostatic disorders and skin issues and highlights promising treatments like casodex and finasteride, but it reports no new clinical results.
1 citations
,
September 2016 in “Acta Chromatographica” This study validated a new RP-HPLC method for accurately determining doxazosin mesylate and finasteride in bulk powders and capsule formulations.
January 2020 in “Archives of urology” This review discusses concerns about persistent side effects of finasteride, such as sexual dysfunction and suicidal ideation, urging the medical community to recognize and address these issues.
This study found that anise ethanol extract at 10% and 20% doses positively influenced hair growth in mice, showing effects similar to Minoxidil.
119 citations
,
July 2016 in “Annals of the New York Academy of Sciences” This review examines the impact of vitamin D signaling in extraskeletal tissues and notes that expected benefits from animal and cell studies have not been consistently replicated in human clinical trials.
46 citations
,
March 2001 in “Journal of endocrinological investigation” This review discusses the use of 5α-reductase inhibitors, particularly finasteride, for treating conditions like benign prostatic hyperplasia, male baldness, and hirsutism, and reports no new clinical results.
27 citations
,
January 1984 in “Pharmacology & Therapeutics” This review discusses androgen manipulation strategies for conditions like benign prostatic hyperplasia and prostatic carcinoma but reports no new clinical results.
19 citations
,
September 2009 in “Journal of Chemical & Engineering Data” This study found that the solubilities of flutamide, dutasteride, and finasteride in supercritical carbon dioxide were effectively modeled using semiempirical equations by Chrastil and Bartle, with varying levels of accuracy.