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Certain 4-azasteroids are effective at blocking the enzyme that processes testosterone in human skin and could help treat acne, excessive hair growth, and male pattern baldness.

Testosterone treatment in trans men increases body and facial hair and may lead to hair loss over time, but severe skin issues are rare.

Nandrolone might increase muscle mass with fewer side effects than testosterone but could cause erectile dysfunction and needs more research.

Testosterone and some of its forms can strongly stimulate oil gland growth in skin.

Testosterone can cause acne and male-pattern baldness, affects hair growth in men and women, and makes male skin more sensitive.

Higher DHT levels are linked to fewer hypogonadism symptoms in men with normal testosterone levels.

Testosterone and its metabolites affect brain functions and could help treat neurological disorders.

Testosterone, progesterone, and levonorgestrel change enzyme levels related to fat production in hamster skin, which could affect skin oil and acne.

Finasteride is not expected to be effective for treating Acne vulgaris.

A three-month treatment with a GnRH agonist significantly lowered androgen levels and 5α-reductase activity in men with benign prostatic hyperplasia.

Dutasteride protects dopamine neurons in Parkinson's mice, but Finasteride doesn't.

5α-reductase inhibitors can interfere with doping tests by masking banned substances.

Finasteride's negative effects on brain tissue in male rats may be reversible after stopping the drug.

New treatments for male hypogonadism are effective and should be personalized.

Finasteride slowly binds to 5-alpha-reductase, affecting enzyme stability and inhibitor potency.

Women with hair loss had higher levels of certain hormones, suggesting a link to a condition like PCOS.

Some plant-based treatments may help with ovary function, insulin resistance, and excess male hormones in PCOS, but more research is needed to confirm their safety and effectiveness.

5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.

The human type II 5α-reductase gene, linked to certain male health conditions, has a specific structure and low similarity to other related genes.

The human type II 5α-reductase gene has a specific structure important for understanding certain medical conditions.

Finasteride caused long-term sexual and non-sexual side effects in young men with hair loss.

Valid method measures finasteride in plasma, simple, fast, and affordable.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Ketoconazole shampoo with finasteride improves hair density in men with hair loss.

Finasteride inhibits enzyme activity in rhesus macaques, suggesting they're useful for evaluating similar drugs.

Dutasteride does not impair mental function in elderly men with enlarged prostate.

The protein ARA70/ELE1 is involved in male pattern baldness, and lower levels of its short form may lead to hair thinning.

Female mice with disrupted 5α-reductase 1 had significant metabolic issues, including stress response problems, insulin resistance, liver fat buildup, and obesity.

Understanding how androgens work is key for creating new treatments for prostate issues and hair/skin conditions.