research Molecular Basis of Androgen Action on Human Sexual Desire
Testosterone significantly affects sexual desire in both men and women, but its impact on women is more complex and influenced by psychological factors.
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research Overexpression of Aldo-Keto Reductase 1C3 in LNCaP Cells Diverts Androgen Metabolism Towards Testosterone Resulting in Resistance to the 5α-Reductase Inhibitor Finasteride
Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.
research Men's Health
The document concludes that various drugs for men's health issues are in development, with treatments for sexual dysfunction and prostate conditions being the most advanced.
research Expression of Steroidogenic Enzymes in Human Sebaceous Glands
Human sebaceous glands contain enzymes that affect androgen production and may influence sebum production and acne.
research Free Androgen Index: Marker of Premature Androgenetic Alopecia in Men
The Free Androgen Index (FAI) is the best indicator of early hair loss in men before age 30.
research Clinical and Laboratory Indicators of Polycystic Ovary Syndrome in Chinese Han Nationality with Different Rotterdam Criteria-Based Phenotypes
Different types of PCOS in Chinese Han women show varying levels of male hormone and metabolic issues.
research Triple Hormonal Blockade (ADT3): A Patient’s Perspective
Triple Hormonal Blockade (ADT3) can effectively manage prostate cancer but requires careful monitoring for heart risks.
research A Review of Hormonal Therapy for Female Pattern (Androgenic) Alopecia
Hormonal therapies like cyproterone acetate and spironolactone may help some women with hair loss, but finasteride 1mg is not useful, and the effectiveness of other treatments is still unclear.
research Is Seborrhea a Sign of Autonomic Impairment in Parkinson's Disease?
Seborrhea in Parkinson's disease may be linked to hormones, not autonomic impairment.
research Dihydrotestosterone Induces p27 Degradation via Direct Binding with SKP2 in Ovarian and Breast Cancer
Dihydrotestosterone causes p27 protein breakdown in ovarian and breast cancer cells by binding with SKP2.
research Anti-Androgenic Activities of the Triterpenoids Fraction of Ganoderma Lucidum
The triterpenoids from Ganoderma lucidum can block testosterone effects and may help treat enlarged prostate.
research Androgen Treatment in Women: A Review of Testosterone Therapy and Its Effects
Testosterone therapy can help improve sexual function, mood, and bone density in women with low androgen levels, but more research is needed on long-term safety.
research Androgen Receptors And Their Biology
Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.
research In Vivo Uptake and Metabolism of Testosterone by the Skin and Other Tissues of the Rat
Rat skin takes up and processes testosterone differently than other organs, with testosterone being more important for the skin than its metabolite 5α-DHT.
research 5α-Reductase Inhibitors: A New Hope in Dermatology?
Finasteride shows promise for treating hair loss and excessive hair growth, but more research is needed to confirm its effectiveness and safety.
research Effect of Testosterone Supplementation With and Without a Dual 5α-Reductase Inhibitor on Fat-Free Mass in Men With Suppressed Testosterone Production
Testosterone's muscle-building effects do not require its conversion to DHT.
research Clinical Pharmacokinetics and Pharmacodynamics of Finasteride
Finasteride helps regrow hair and shrink prostate by reducing DHT, with some sexual side effects.
research 5α-Reductase Inhibitors and Prostatic Disease
5α-Reductase inhibitors can help treat hair loss, acne, and prostate issues by reducing DHT levels.
research Testosterone And Dihydrotestosterone Production In Genetically Furless And Furred Male Rabbits And Effects On Growth
Furless male rabbits grew slightly faster and heavier than furred ones, but testosterone levels were not the cause.
research Established Risk Factors for Coronary Heart Disease Are Unrelated to Androgen-Induced Baldness in Female-to-Male Transsexuals
Baldness caused by male hormones in female-to-male transsexuals doesn't increase the risk of heart disease.
research Darwinian Health and Other Contradictions
The document concludes that understanding health requires considering evolutionary perspectives on reproductive fitness, and recognizing the complexity of factors like diet, testosterone, and sexual orientation.
research The Metabolism and Control Mechanism of Human Hair Follicles
Human hair follicles have a unique metabolism that changes between growth stages and may contribute to baldness.
research Markers of Peripheral Androgen Action In Vivo and In Vitro
Dihydrotestosterone (DHT) is crucial for conditions like male-pattern baldness and acne, and measuring a byproduct, androstanediol glucuronide, is a better way to assess DHT's effects than DHT blood levels.
research Finasteride, a Type 2 5α-Reductase Inhibitor, in the Treatment of Men with Androgenetic Alopecia
Finasteride effectively treats male hair loss, improving growth and density.
research Hair Growth Promoting Activity of Helianthus Annuus in Testosterone Induced Alopecia in Mice Model
Sunflower oil was found to promote hair growth in mice with hormone-induced hair loss.
research Androgenetic Alopecia in a Postmenopausal Woman Due to Ovarian Hyperthecosis
Hair loss in postmenopausal woman caused by ovarian issue.
research Androgens and Hair Growth
Androgens can both increase and decrease hair growth in different parts of the body.
research 5α-Reductase Inhibitors: The Finasteride Story
Finasteride safely treats enlarged prostate and male-pattern baldness.
research 5α-Reductases in Human Physiology: An Unfolding Story
Enzymes called 5α-reductases have many body functions and need more research to safely use inhibitors.
research Finasteride: The First 5α-Reductase Inhibitor
Finasteride treats enlarged prostate and baldness, but may cause limited urinary improvement and sex-related side effects.