24 citations
,
January 2012 in “Indian Journal of Dermatology, Venereology and Leprology” This study suggests that hypersensitivity and increased serum IgE levels might contribute to the pathogenesis of diffuse alopecia areata through intense local inflammatory infiltration.
23 citations
,
September 2019 in “Dermatology practical & conceptual” This study analyzed the features of alopecia areata incognita and diffuse alopecia areata, finding distinct patterns in hair loss regions and trichoscopic signs, and noted a benign course responsive to topical steroid therapy.
23 citations
,
June 1993 in “PubMed” This study found that a vitamin B-group and L-cystine combination therapy improved hair quality and growth in women with diffuse effluvia, with one formulation showing greater efficacy than another and both performing better than placebo.
21 citations
,
October 2007 in “Australasian Journal of Dermatology” This case study reported that a 62-year-old woman with alopecia areata experienced significant hair regrowth with completely non-pigmented white hair following a 2-month course of oral prednisolone.
19 citations
,
February 2016 in “Journal of The American Academy of Dermatology” This study found that the presence of CD3(+) T-cells within empty follicular fibrous tracts is a reliable indicator for diagnosing diffuse alopecia areata instead of pattern hair loss.
19 citations
,
January 2015 in “Journal of Clinical and Diagnostic Research” This study found that telogen effluvium was the most common type of diffuse hair loss among women, with psychological stress and iron deficiency anemia being significant contributing factors.
18 citations
,
January 2018 in “BMC dermatology” This paper describes a case of epidermolysis bullosa simplex with muscular dystrophy associated with a novel PLEC mutation and diffuse alopecia, highlighting a potential genetic link that remains uncertain.
18 citations
,
January 1997 in “British Journal of Dermatology” In this study, five women with androgenetic alopecia developed severe hypertrichosis on the face and limbs after using 5% topical minoxidil, which resolved after discontinuing the treatment.
16 citations
,
January 2020 in “Annals of the rheumatic diseases” In this study, baricitinib improved the resolution of arthritis or rash in patients with systemic lupus erythematosus, but outcomes for skin involvement like alopecia were not reported.
16 citations
,
March 2017 in “Bone Marrow Transplantation” In this study, permanent alopecia after haematopoietic stem cell transplantation was found in 16% of patients and was significantly associated with conditioning regimens involving busulphan.
16 citations
,
February 1999 in “American Journal of Dermatopathology” This article describes a woman's case of slowly progressive nonscarring alopecia with unique biopsy findings, suggesting the need to reexamine similar cases currently classified as chronic diffuse alopecia areata.
16 citations
,
August 1989 in “PubMed” This study concluded that high-dose oral therapy with L-cystine, gelatin, and vitamin A significantly improved hair growth indicators in patients with diffuse hair loss, with no systemic side effects observed.
15 citations
,
January 2016 in “International journal of trichology” This study found that female students experiencing diffuse hair fall had significantly lower Vitamin D3 levels compared to healthy controls.
15 citations
,
December 2011 in “Journal of the European Academy of Dermatology and Venereology” In this study, severe diffuse hair loss in patients with systemic lupus erythematosus was associated with distinct clinical, dermoscopic, and histopathological features, which improved alongside treatment of the underlying condition.
15 citations
,
May 2003 in “American Journal of Kidney Diseases” This case report describes a hemodialysis patient whose hair loss reversed after switching from tinzaparin to enoxaparin, suggesting tinzaparin-induced alopecia.
11 citations
,
January 2015 in “Current problems in dermatology” This review discusses the evaluation and management of male baldness and related conditions, but reports no new clinical results.
10 citations
,
August 2016 in “Oxford Medical Case Reports” This case report describes the development of halo naevi, vitiligo, and diffuse alopecia areata in a 33-year-old woman undergoing tocilizumab therapy, suggesting a link between these conditions and cellular and humoral immune factors.
10 citations
,
July 2012 in “International Journal of Dermatology” This article addresses diffuse pattern essential syphilitic alopecia as an unusual form of secondary syphilis but provides no new clinical findings.
9 citations
,
March 2014 in “TURKDERM” This review discusses nutritional factors important for hair growth and the need to assess and address deficiencies in cases of alopecia, but does not report new clinical results.
9 citations
,
October 2012 in “PubMed” This study observed that telogen effluvium was the most common pattern of diffuse hair loss among 100 female patients, often associated with factors like stress and fever.
9 citations
,
April 2005 in “PubMed” This study found that diffuse alopecia in female squirrel monkeys is associated with chronic telogen effluvium and appears to be predominantly age-related, potentially serving as an animal model for human diffuse alopecia.
7 citations
,
January 2018 in “International Journal of Dermatology” Syphilis can cause hair loss without other symptoms and should be considered when diagnosing unexplained hair loss.
7 citations
,
January 2001 in “PubMed” This study found that vitamin B6 injections over several weeks improved hair condition and reduced hair loss in some women with diffuse alopecia, while calcium pantothenate had no clear positive effect.
6 citations
,
January 2021 in “Journal of Nutritional Science and Vitaminology” This study found that oral vitamin D3 therapy significantly improved hair regrowth in women with telogen effluvium in southern Punjab, Pakistan, especially among younger women not using sunscreen but consuming milk or milk protein.
6 citations
,
January 2020 in “Postepy Dermatologii I Alergologii” This article recommends assessing serum ferritin and vitamin D levels in patients with diffuse hair loss before starting treatment, but it reports no new clinical results.
6 citations
,
July 2015 in “European Journal of Dermatology” Stopping methotrexate might reverse lymphoma-like conditions in some patients.
6 citations
,
April 2015 in “Infection” This case study describes a patient with secondary syphilis, including alopecia syphilitica diffusa, whose symptoms resolved completely after treatment with benzylpenicillin following prednisolone prophylaxis.
6 citations
,
January 2015 in “Indian Dermatology Online Journal” This study observed that an overdose of levothyroxine in a hypothyroid infant led to rapid hair loss, which improved after reducing the medication dose.
5 citations
,
February 2017 in “Australasian Journal of Dermatology” This report describes three cases of hair loss that appear consistent with cicatricial pattern hair loss, a possible new subtype of scarring alopecia presenting in a female pattern hair loss distribution.
4 citations
,
October 2019 in “Case Reports” This report describes the first known case of diffuse idiopathic skeletal hyperostosis in a woman under 40, associated with both metabolic syndrome and polycystic ovarian syndrome.