67 citations
,
January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” This review discusses the causes, associated conditions, and treatment options for alopecia areata, such as corticosteroids and wigs, but reports no new clinical findings.
66 citations
,
June 2021 in “Journal of The American Academy of Dermatology” In this phase 2 study, baricitinib at 2 mg and 4 mg doses significantly improved hair regrowth in adults with alopecia areata and ≥50% scalp hair loss compared to placebo, without new safety concerns, although the small sample size limits the results' generalizability.
56 citations
,
January 2019 in “Skin appendage disorders” In this multicenter study, androgenetic alopecia was the most common type of alopecia among both men and women attending specialty hair clinics on four continents.
53 citations
,
January 2007 in “Dermatology” This study suggests that chemotherapy-induced anagen effluvium represents patterned hair loss, with most patients retaining hairlines, but patterns do not vary significantly by age, symptoms, or chemotherapy type.
51 citations
,
January 2014 in “Pediatric Clinics of North America” This article examines various types of childhood alopecia and highlights the importance of identifying chronic conditions or those linked to underlying medical issues, but reports no new results.
51 citations
,
December 2011 in “The Journal of Dermatology” This review discusses updated treatment guidelines for alopecia areata in Japan, highlighting new options like corticosteroid pulse therapy, but reports no new clinical results.
50 citations
,
March 2000 in “American Journal of Clinical Dermatology” This article discusses the etiology, clinical features, and treatment of alopecia areata but presents no new clinical findings, underlining the palliative nature of current therapies.
49 citations
,
January 2003 in “American Journal of Clinical Dermatology” This review discusses various pediatric hair loss conditions and treatments, highlighting the importance of a holistic approach and noting that no single treatment is universally effective.
49 citations
,
April 2000 in “Journal of The American Academy of Dermatology” This article discusses the etiology, clinical features, diagnosis, histopathology, and treatment of alopecia areata but reports no new clinical findings; it emphasizes the palliative nature of current treatments.
45 citations
,
December 2014 in “Journal of the European Academy of Dermatology and Venereology” This study found that plasmacytoid dendritic cells are central to the pathogenesis of alopecia areata, suggesting they may help differentiate it from trichotillomania and androgenetic alopecia.
44 citations
,
November 1998 in “Australasian Journal of Dermatology” This review provides a framework for diagnosing acquired scalp alopecias and discusses both non-scarring and scarring types, but reports no new clinical results.
43 citations
,
August 2013 in “Pediatric Dermatology” This review discusses the use of trichoscopy in diagnosing and managing pediatric hair and scalp disorders and reports no new experimental findings.
42 citations
,
October 2012 in “Dermatologic Clinics” This article reviews the use of trichoscopy for diagnosing common hair and scalp diseases and introduces a new classification for specific skin surface abnormalities, without presenting new clinical results.
40 citations
,
July 2017 in “Frontiers in Medicine” This review highlights that in children, hair loss can be attributed to diverse conditions like alopecia areata and tinea capitis, and stresses the importance of a holistic approach to diagnosis and management, including psychosocial support due to limited effective treatments.
39 citations
,
November 2017 in “Journal of The American Academy of Dermatology” This review presents standardized methods for assessing and tracking hair loss in alopecia areata but reports no clinical results, with the authors noting time limitations in clinical practice.
35 citations
,
May 2012 in “Expert Opinion on Pharmacotherapy” This review summarizes current and emerging treatments for common hair loss conditions, highlighting good evidence for androgenetic alopecia but noting the lack of long-term data for alopecia areata and cicatricial alopecias.
32 citations
,
December 2017 in “International Journal of Molecular Sciences” This review suggests that decreased serum 25-hydroxyvitamin D levels may play a role in different types of non-scarring alopecia, but further studies are needed to explore vitamin D supplementation as a therapeutic option.
31 citations
,
March 2017 in “Journal of The American Academy of Dermatology” This study observed various patterns of permanent alopecia in breast cancer patients treated with taxanes and adjuvant hormonal chemotherapy, hypothesizing disruptions in hair follicle cycles due to chemoinflammatory and hormonal factors.
30 citations
,
May 2004 in “Journal der Deutschen Dermatologischen Gesellschaft” This review proposes a classification system for childhood hair loss based on clinical appearance, age of onset, and associated symptoms, but reports no new clinical results.
30 citations
,
August 1983 in “Pediatric Clinics of North America” Most hair loss in children is caused by a few common conditions, and it's important to diagnose these properly and support the child's mental health.
29 citations
,
December 2017 in “International Journal of Dermatology” This study found that vitamin D deficiency in patients with alopecia areata was associated with greater disease severity and longer duration, but not with disease pattern or vitamin D receptor expression.
29 citations
,
August 2008 in “Current Opinion in Pediatrics” This review discusses the most common types of alopecia in adolescents and emphasizes the importance of psychosocial support, but reports no new clinical findings.
28 citations
,
September 1998 in “Medical Clinics of North America” This article reviews common causes of hair loss, noting that a well-directed history and examination are often sufficient for diagnosis, and reports no new clinical findings.
27 citations
,
May 2007 in “Archives of dermatological research” In this study, alopecia areata patients treated with diphencyprone showed a significant increase in CD8 lymphocytes around hair bulbs, which may be associated with hair regrowth.
26 citations
,
October 2020 in “Pediatric Dermatology” This study found that oral tofacitinib led to clinically significant improvement in alopecia areata severity scores among pre-adolescents, though results varied and further evaluation in clinical trials is needed.
24 citations
,
January 2015 in “Current problems in dermatology” This review discusses diagnostic challenges and management approaches for pediatric hair disorders, emphasizing the importance of distinguishing between acquired and congenital conditions, and reports no clinical results.
23 citations
,
April 2021 in “Journal of Clinical Medicine” This review compiles existing data on frontal fibrosing alopecia and highlights the promise of 5-alpha reductase inhibitors as a treatment option, while noting the need for clarity on its cause and progression.
23 citations
,
November 2020 in “Central-European Journal of Immunology/Central European Journal of Immunology” This review explores the autoimmune hypothesis of alopecia areata and the possible genetic and melanogenesis-associated autoantigens, but reports no new clinical findings.
23 citations
,
October 2018 in “Australasian Journal of Dermatology” This review highlights that frontal fibrosing alopecia’s increasing incidence may involve immune, genetic, hormonal, and environmental factors, yet its pathogenesis remains complex and not fully understood.
22 citations
,
June 2013 in “Australasian Journal of Dermatology” Early stage bald spots are linked to skin inflammation and damage to the upper part of the hair follicle.