6 citations
,
November 2022 in “Journal of autoimmunity” This case report discusses a successful treatment of Alopecia Areata with tofacitinib and includes a literature review on the condition's pathophysiology and the mechanism of JAK inhibitors, though it notes the high failure rate of available treatments and absence of FDA-approved options.
1 citations
,
August 2023 in “Clinical Cosmetic and Investigational Dermatology” This study found that exclamation mark hairs are the only trichoscopic feature that can differentiate clinically suspicious SA from AA.
290 citations
,
August 2021 in “Clinical Reviews in Allergy & Immunology” JAK inhibitors show promise for treating alopecia areata, but more research is needed.
106 citations
,
January 2013 in “Clinical and Developmental Immunology” This review discusses the pathogenesis of alopecia areata, highlighting the role of immune privilege collapse in hair follicles but reports no clinical results.
44 citations
,
August 2014 in “Anais brasileiros de dermatologia/Anais Brasileiros de Dermatologia” This study found that methotrexate may be an effective and safe treatment option for severe alopecia areata, with better regrowth results when combined with corticosteroids.
37 citations
,
December 2021 in “Cells” This study found that dysregulation of systemic Th1, Th2, and Th17 cytokines is associated with alopecia areata, with specific cytokines linked to disease activity and treatment response.
23 citations
,
October 2020 in “Anais brasileiros de dermatologia/Anais Brasileiros de Dermatologia” This consensus report outlines Brazilian dermatologists' recommendations for treating alopecia areata, highlighting intralesional corticosteroids for localized cases and systemic therapy for extensive, active disease, along with monitoring side effects.
21 citations
,
April 2025 in “MedComm” This review explores the complex factors involved in alopecia areata, such as immune and genetic influences, and discusses advances in diagnostic and therapeutic approaches, while reporting no new clinical results.
14 citations
,
April 2017 in “Dermatology practical & conceptual” This study reports that yellow dots in a higher number per field of vision were the most consistent dermoscopic finding in severe cases of alopecia areata.
10 citations
,
January 2023 in “Journal of the European Academy of Dermatology and Venereology” This review highlights the significant negative impact of alopecia areata on quality of life, mental health, and work, calling for individualized approaches and effective treatments to mitigate these effects.
7 citations
,
March 2024 in “Skin Research and Technology” This study identified miR-200c-3p as influencing key genes in the EGFR resistance pathway, suggesting its potential theranostic role in addressing issues related to this pathway.
6 citations
,
February 2021 in “Advances in Clinical and Experimental Medicine” In this study, patients with alopecia areata received a single intradermal injection of Wharton's jelly-derived mesenchymal stem cells, resulting in an average hair regrowth of 67% at treated sites within 24 weeks, demonstrating both efficacy and safety without side effects.
5 citations
,
December 2024 in “Anais Brasileiros de Dermatologia” This study outlines treatment options for alopecia, suggesting intralesional corticosteroids for localized adult cases and Janus Kinase inhibitors for severe cases, emphasizing a balance between hair regrowth rate and managing side effects.
5 citations
,
April 2015 in “HSOA journal of clinical dermatology & therapy” This article reviews alopecia areata treatments, noting varied outcomes, and reports no new clinical results.
4 citations
,
October 2024 in “Journal of the American Academy of Dermatology” Abrocitinib may help treat alopecia areata effectively with mild side effects.
4 citations
,
January 2023 in “Medical Journal of Babylon” This clinical trial found that hemp seed oil may be a promising treatment for localized alopecia areata, with notable hair regrowth observed in some patients after eight weeks of use.
4 citations
,
October 2022 in “Genes” This review discusses the role of cutaneous and intestinal microbiota in the development of alopecia areata, summarizing current literature without reporting new clinical results.
4 citations
,
January 2020 in “Skin appendage disorders” This case report describes a unique presentation of frontal fibrosing alopecia characterized by a hair loss pattern that resembles the Greek letter upsilon, supported by trichoscopic and histological findings.
4 citations
,
October 2018 This review discusses the assessment and management of common causes of pediatric alopecia, highlighting the importance of dermatologist referral for unclear diagnoses, treatment failures, or scarring alopecia, and reports no new clinical findings.
4 citations
,
January 2017 in “Indian Dermatology Online Journal” This case study describes severe hypertrichosis in a 3-year-old with alopecia areata after unsupervised use of high-dose topical minoxidil, highlighting the need to avoid such practices in children.
3 citations
,
June 2025 in “Biomedicines” This review discusses the potential link between gut microbiota alterations and the onset and progression of alopecia areata, identifying it as a possible pathogenetic factor and therapeutic target, but reports no new clinical results.
3 citations
,
January 2018 in “Skin Appendage Disorders” This case report describes two instances of habit tic nail deformities associated with alopecia areata.
2 citations
,
February 2025 in “Medicine” This study found that among individuals with hair loss-related conditions, there was a significant association between alopecia and anxiety disorders, with affected individuals experiencing anxiety more frequently.
2 citations
,
December 2022 in “Journal of the American Academy of Dermatology” This study reported that in Hispanic/Latinx patients with alopecia areata, rheumatoid arthritis was a common autoimmune comorbidity, and gastroesophageal reflux disease was notably more prevalent than in other populations with alopecia areata.
1 citations
,
December 2025 in “Photodermatology Photoimmunology & Photomedicine” This study found that early initiation of phototherapy is an effective treatment strategy for certain subtypes of AA, particularly in older patients and those with a shorter disease duration.
1 citations
,
March 2025 in “Pediatric Dermatology” This review highlights the evolution of assessment tools for alopecia areata, revealing newer tools that evaluate beyond scalp hair loss, including psychosocial impact and disease chronicity, which can aid clinicians in developing individualized treatment strategies and enhance research in pediatric dermatology.
1 citations
,
April 2023 in “Frontiers in Immunology” This review explored recent research on the immune mechanisms and potential therapeutic targets for alopecia areata, highlighting the roles of immune-related cells, autocrine and paracrine signaling, as well as factors like adipose-derived stem cells and gut microbiota in disease pathogenesis.
1 citations
,
March 2023 in “Clinical, Cosmetic and Investigational Dermatology” This review discusses recent advances in understanding and treating alopecia areata, emphasizing the ongoing challenges and unmet needs in disease management; it reports no new clinical findings.
1 citations
,
September 2021 in “CRC Press eBooks” This chapter reviews trichoscopic-pathologic correlations in Frontal Fibrosing Alopecia and reports no new clinical results; the authors discuss genetics, clinical patterns, and unusual variants associated with this condition.
July 2026 in “Applied Sciences” This review suggests that 308 nm excimer therapy may offer a well-tolerated non-pharmacologic option for alopecia areata, with more limited evidence for its effectiveness in lichen planopilaris and frontal fibrosing alopecia.