September 2016 in “Journal of The American Academy of Dermatology” This case study identified the condition as Monilethrix in a 17-year-old female, characterized by a beaded hair appearance and linked to a genetic cause.
44 citations
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January 1997 in “British Journal of Dermatology” In this study, five women with androgenetic alopecia experienced severe facial and limb hypertrichosis after using 5% topical minoxidil, which resolved after discontinuing the treatment.
18 citations
,
January 1997 in “British Journal of Dermatology” In this study, five women with androgenetic alopecia developed severe hypertrichosis on the face and limbs after using 5% topical minoxidil, which resolved after discontinuing the treatment.
1 citations
,
October 2021 in “Australasian Journal of Dermatology” This letter to the editors describes a case of diffuse congenital hypotrichosis simplex with associated hair shaft fragility but reports no new clinical findings.
September 2024 in “Dermatology Online Journal” This report describes a case where a 24-year-old woman developed severe ear and face hypertrichosis after using 5% topical minoxidil, which resolved three months after discontinuation.
16 citations
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August 2002 in “Journal of Interferon and Cytokine Research” In this case study, hypertrichosis in a patient with hemophilia and hepatitis C may have been induced by IFN-alpha treatment, despite the drug usually causing hair loss.
August 2024 in “Dermatology and Therapy” This report describes a case where a 44-year-old male treated with vorasidenib for diffuse low-grade gliomas developed unexpected hair growth, including in areas of severe hair loss, after one month, highlighting a previously undocumented side effect.
20 citations
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March 1994 in “Clinical and Experimental Dermatology” In this case report, a 16-year-old girl developed generalized hypertrichosis after using excessive doses of topical minoxidil for diffuse alopecia, which resolved four months after stopping treatment.
1 citations
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August 2011 in “Dermatology Reports” This case report describes a new family with autosomal recessive hypotrichosis simplex with woolly hair, suggesting the disorder may be underreported due to misdiagnosis.
40 citations
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May 1999 in “Journal of The European Academy of Dermatology and Venereology” This article outlines management guidelines for androgenetic alopecia, highlighting that continued treatment with medications like finasteride or minoxidil typically halts progression and improves hair condition in most mild to moderate cases.
1 citations
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January 2018 in “Jornal Brasileiro de Patologia e Medicina Laboratorial” This case report describes a 10-year-old girl with monilethrix, detailing hereditary autosomal dominant traits and distinctive nodular hair shaft abnormalities observed in her family through clinical examination and microscopic analysis.
This review discusses anticoagulant and antihypertensive medications as potential contributors to medication-induced telogen effluvium and reports no new clinical results.
March 1997 in “Journal of Endocrinology/Journal of endocrinology” Excessive hair growth in women can be treated with medications like spironolactone and finasteride, and male-pattern baldness in women can be improved with similar treatments.
May 2014 in “JAMA Dermatology” Mother and son diagnosed with a rare genetic hair loss condition with no effective treatment.
17 citations
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January 1991 in “Acta Dermato Venereologica” This report describes a Danish family with autosomal dominant hypotrichosis, where affected members experienced gradual diffuse hair loss leading to near-total scalp alopecia by ages 14-21.
2 citations
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December 2004 in “Medicine” This review discusses various causes of hair loss, emphasizing the importance of a structured diagnostic approach, and reports no new clinical findings.
December 1990 in “PubMed” This review discusses various adverse drug reactions affecting hair, such as hair loss, hypertrichosis, and color changes, and emphasizes their generally reversible nature if the causative drug is discontinued.
1 citations
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April 2015 in “International Journal of Pediatrics and Adolescent Medicine” This case report describes a patient with hemophagocytic lymphohistiocytosis who developed hypertrichosis and eyelash trichomegaly, likely linked to cyclosporine-A and prednisolone therapy, with expected resolution after stopping treatment.
September 2025 in “Editora Pasteur eBooks” Low-dose oral minoxidil is as effective as or better than topical minoxidil for hair growth but may cause mild side effects.
May 2017 in “Journal of the American Academy of Dermatology” Monilethrix is a rare, inherited condition causing fragile hair and hair loss, with no cure but some treatments may help.
31 citations
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August 2001 in “PubMed” This study found that the TrichoScan method detected significant increases in hair counts and cumulative hair thickness in men after finasteride treatment, suggesting its potential for monitoring hair treatment responses.
15 citations
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April 2020 in “Journal of The American Academy of Dermatology” This article discusses the challenges of treating lichen planopilaris, reviews various therapeutic options including minoxidil, and reports no new clinical findings.
20 citations
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February 2015 in “Anais brasileiros de dermatologia/Anais Brasileiros de Dermatologia” This case report describes a 6-year-old girl diagnosed with monilethrix despite no familial history and treated with a topical minoxidil trial.
January 2026 in “Cosmoderma” In this clinical case study, a 9-year-old girl was diagnosed with monilethrix, a hereditary hair shaft disorder characterized by weak, beaded hair, with management focusing on minimizing hair trauma.
55 citations
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November 2018 in “American journal of human genetics” This study identified five mutations in the gene LSS in individuals with unexplained hypotrichosis simplex, highlighting a potential role of mislocalized LSS proteins in disrupting hair follicle biology.
42 citations
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September 2000 in “British Journal of Dermatology” This report describes two children with congenital hypotrichosis and found their short hair is due to a shortened anagen phase, with the condition resolving spontaneously during puberty.
7 citations
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May 2010 in “Journal of Cutaneous Pathology” This study identified a novel locus for hereditary hypotrichosis simplex on chromosome 13q12.12~12.3 in a four-generation Chinese family.
January 2026 in “International Journal of Dermatology Research” This case report discusses a young girl with loose anagen hair syndrome, highlighting the importance of recognizing the condition early to avoid misdiagnosis and unnecessary treatments, and noting her spontaneous improvement with conservative management.
9 citations
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March 2018 in “European journal of dermatology/EJD. European journal of dermatology” This study in a Pakistani family identified a novel ST14 gene variant as the likely genetic cause of autosomal recessive ichthyosis with hypotrichosis syndrome.
74 citations
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January 2006 in “The journal of investigative dermatology/Journal of investigative dermatology” This study identified novel compound heterozygous mutations in the DSG4 gene in a Japanese patient with congenital hypotrichosis, suggesting overlap between localized autosomal recessive hypotrichosis and monilethrix.