January 2015 in “Indian Dermatology Online Journal” This diagnostic discussion reports that diffuse alopecia areata was identified in a patient with diffuse hair loss, based on specific histopathological features observed in a biopsy.
Patient history is key in diagnosing hair loss types.
January 2014 in “International Journal of Dermatology and Venereology” This case report describes a 42-year-old male with alopecia areata and a scalp neurofibroma, emphasizing the tumor's histopathological features and the patient's decision against surgical treatment.
January 2014 in “Astrocyte” This study found that among women with diffuse hair loss, 26.2% had a history of drug intake, with antihypertensives being the most common drug group implicated.
March 2013 in “Journal für Kardiologie (Krause & Pachernegg GmbH)” This review discusses the role of various hormones in diffuse hair loss and emphasizes the need for further research to clarify their complex interactions and potential therapeutic implications, but reports no new clinical results.
December 2008 in “中華皮膚科醫學雜誌” This case report describes a 35-year-old Taiwanese man whose hair loss improved significantly after treatment for syphilis, suggesting a link between his condition and the infection.
April 2021 in “Libyan journal of medical sciences” This case report documented alopecia as a rare complication of SARS-CoV-2 infection in a 33-year-old woman, with hair loss improving after treatment.
April 2018 in “Rossiiskii Zhurnal Kozhnykh i Venericheskikh Boleznei” This study observed that patients with different types of alopecia exhibited variable epidermal thickness and consistent dermal changes, including hair follicle destruction and lymphohistiocytic infiltrates, which may suggest inflammation.
April 2004 in “Inpharma Weekly” Melatonin helps hair growth in women with hair loss issues.
137 citations
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July 2004 in “Journal of The American Academy of Dermatology” This study observed that triple horizontal scalp biopsies provided a more accurate diagnosis of female pattern hair loss in women than a single horizontal biopsy, especially for those with advanced hair loss.
83 citations
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November 2002 in “British Journal of Dermatology” This study found no direct relationship between low serum ferritin and chronic diffuse telogen hair loss in women, questioning the usefulness of serum ferritin measurement and iron supplementation for managing this condition.
64 citations
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November 2008 in “Journal of The American Academy of Dermatology” This study observed that acute diffuse and total alopecia, a subtype of alopecia areata, typically resolves rapidly and spontaneously within about six months, even without treatment, suggesting a favorable prognosis.
59 citations
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January 2002 in “Dermatology” This study suggests the existence of a new subtype of alopecia, called 'acute diffuse and total alopecia of the female scalp (ADTAFS)', characterized by acute, diffuse hair loss primarily in women and a rapid recovery.
42 citations
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January 2008 in “Dermatology” This study reports that dermoscopy is a useful diagnostic tool for distinguishing acute diffuse and total alopecia of the female scalp from female pattern hair loss by identifying specific hair features.
20 citations
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March 2019 in “Case Reports in Dermatology” This report describes two cases where patients developed alopecia while undergoing treatment for psoriasis with IL-17 inhibitors, suggesting an unexpected paradoxical reaction.
17 citations
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May 2018 in “Journal of Cosmetic Dermatology” This study reports that nonscarring diffuse hair loss in women is most common in the 21-40 age group, with low serum ferritin, vitamin B12, and vitamin D3 levels contributing to its pathogenesis.
10 citations
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June 2003 in “British Journal of Dermatology” This article challenges the idea that low serum ferritin is not associated with chronic diffuse telogen hair loss by questioning the validity of 'normal' serum ferritin reference ranges.
8 citations
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January 2015 in “International journal of trichology” In this case report, the authors describe complete recovery from acute diffuse and total alopecia linked to Borrelia infection after treatment with intravenous ceftriaxone and topical clobetasol foam.
7 citations
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November 2006 in “Pediatric Dermatology” This article describes the first reported case of alopecia in a neonate with congenital syphilis.
6 citations
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April 2021 in “Frontiers in Immunology” This study presents the first documented case of dramatic hair regrowth in a systemic lupus erythematosus patient with refractory alopecia following tofacitinib therapy, suggesting a potential new application for JAK inhibitors in difficult-to-treat cutaneous SLE manifestations.
4 citations
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May 1989 in “Journal of the Royal Society of Medicine” Crohn's disease can cause hair loss before other symptoms appear.
1 citations
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May 2025 in “The Journal of Dermatology” In this study, increased Treg cell activity indicated by IL-10 and IL-15 was identified as a feature of ADTA, distinguishing it from AA and potentially explaining ADTA's more favorable prognosis.
June 2026 in “International Journal of Homoeopathic Sciences” This case report from Dr Batra’s® Homeopathy Clinic describes significant improvement in a middle-aged woman's chronic hair loss and scalp visibility through individualized homeopathic treatment, nutritional adjustments, and regular monitoring over a year, as evidenced by patient-reported outcomes and clinical assessments.
January 2026 in “International Journal of Dermatology” This study reports two cases where acquired perforating dermatosis was localized to the scalp and coincided with acute diffuse alopecia, suggesting perifollicular inflammation may link the two conditions.
September 2025 in “International Journal of Trichology” This study found that a recent outbreak of diffuse hair loss in Maharashtra's Buldhana district was linked to anagen effluvium, possibly caused by high selenium levels, along with strontium and zinc excess in patients' serum and local water sources.
May 2024 in “World Journal Of Advanced Research and Reviews” This study found that females with chronic diffuse hair loss, including chronic telogen effluvium and female pattern hair loss, had significantly lower serum ferritin levels compared to controls, suggesting a strong association between decreased iron stores and hair loss.
January 2024 in “Современные проблемы науки и образования (Modern Problems of Science and Education)” Treating post-COVID hair loss leads to full recovery, while not treating it often results in ongoing symptoms.
November 2023 in “International Journal of Dermatology” In this study, researchers analyzed histopathologic findings in 32 women with chronic diffuse alopecia and found that 40.6% had androgenetic alopecia, while a diffuse variant of lichen planopilaris was diagnosed in 32.5% of cases, emphasizing the importance of histopathologic examination for accurate diagnosis.
September 2023 in “Journal of the American Academy of Dermatology” Increased Treg cells and IL-10 may help quick recovery in acute diffuse and total alopecia.
January 2023 in “Voennaâ medicina” This case study illustrates the successful treatment of chronic diffuse telogen effluvium in a young woman attributed to latent iron deficiency and emphasizes the importance of comprehensive assessment in similar cases.