23 citations
,
October 2007 in “International journal of cancer” This study reports that hair from women with breast cancer showed a unique X-ray diffraction feature, potentially offering a non-invasive method for detecting the disease.
17 citations
,
June 2001 in “Journal of the National Cancer Institute” A specific hair diffraction pattern may indicate breast cancer if tested with the correct method.
June 2026 in “Journal of Cutaneous Pathology” This study found that polarized light microscopy is more effective than diffractive microscopy in distinguishing scarring from non-scarring alopecia, providing a highly specific adjunct diagnostic tool for alopecia biopsy specimens.
66 citations
,
June 2004 in “Biophysical Journal” Hard α-keratin in hair has a unique, nonordered structure, different from other fibers.
8 citations
,
July 2002 in “X-Ray Spectrometry” In this study, researchers found a correlation between x-ray patterns and the element composition of human hair, with certain metal roles in the hair matrix considered.
7 citations
,
January 2011 in “Biochemistry Research International” This study confirms that the proposed universal model for hard α-keratin structure applies to all known forms across various mammalian species.
1 citations
,
January 2015 in “Bulletin of the Russian Academy of Sciences Physics” This review examines the effects of various factors on the molecular and nanostructural ordering of human hair, highlighting its potential as a diagnostic material for environmental and public health monitoring, but reports no new experimental results.
January 1980 in “中国科学A辑(英文版)” This study found that the molecular structures of α-keratin and collagen in a 2,100-year-old female cadaver's hair and tendon were preserved, while fibrous molecule aggregations were altered.
12 citations
,
January 2009 in “Breast Cancer Basic and Clinical Research” This study found that the combination of mammography and hair X-ray diffraction increased sensitivity for detecting breast cancer compared to using each method alone.
2 citations
,
November 2024 in “PLoS ONE” This study assessed breeding value estimation methods for Korean Sapsaree dogs, finding varied accuracy across BLUP approaches and identifying significant genomic regions affecting traits like body height and hair length. The researchers suggest these findings can enhance breeding strategies for this culturally significant breed.
5 citations
,
September 2014 in “Journal of Pharmaceutical Sciences” 30 citations
,
July 2000 in “PubMed” This study used advanced analytical techniques to reveal that proteins and lipids are distributed unevenly in hair, with distinct structural differences depending on their location within the fiber.
March 2017 in “Jurnal materi dan pembelajaran fisika” This review discusses applications of light diffraction in healthcare, highlighting its use in LASIK procedures, optogenetics, and measuring hair diameter, but reports no new results.
1 citations
,
October 2023 in “Heliyon” In this study, the researchers reported a new case of Hutchinson-Gilford progeria syndrome with a novel LMNA mutation and successful surgical intervention for airway obstruction.
70 citations
,
June 1998 in “Polymer” This study found that permanent waving treatment partially disrupts the α-helical structure in human hair microfibrils, primarily during the initial reduction phase, rather than just affecting disulphide bonds.
66 citations
,
February 2010 in “CrystEngComm” Made 8 minoxidil samples; 1 cocrystal, 7 salts formed.
42 citations
,
January 2005 in “Applied spectroscopy” In this study, hair samples from breast cancer patients showed increased β-sheet structures and lipid content, with spectral markers successfully identifying cancer in a blind test but also producing false positives.
37 citations
,
October 2015 in “PeerJ” This study found that shampoo and conditioner do not alter hair's molecular structure, while perming treatments significantly affect keratin and intermediate filament structures due to bond alterations.
31 citations
,
February 2007 in “Journal of Structural Biology” Oxidation changes the structure of hair protein filaments, causing them to compact and rearrange.
26 citations
,
March 1986 in “Clinical and Experimental Dermatology” Scalp hair grows at 0.37 mm/day, forearm hair at 0.18 mm/day, and thigh hair at 0.30 mm/day, with no significant differences found in people with certain hair conditions.
24 citations
,
June 2003 in “Journal of Structural Biology” This study suggests that varying intersheet interactions may explain the differences between the two polymorphic forms of macrofibril assembly in Merino wool and hair.
23 citations
,
June 2017 in “Drug Design Development and Therapy” This study found that the dimethyl-β-cyclodextrin inclusion system significantly improved the solubility and bioavailability of finasteride compared to the drug alone, enhancing its absorption rate.
21 citations
,
December 2011 in “Chungara” This study shows that environmental contamination affects mummy hair, suggesting that using it to assess ancient people's health or nutrition should be approached cautiously.
21 citations
,
September 2011 in “Journal of Pharmaceutical Sciences” This study found that the desolvation of finasteride hydrate solvates is highly dependent on the physical environment, complicating investigations but providing insight through complementary analysis techniques.
15 citations
,
January 2018 in “Advances in experimental medicine and biology” This review discusses recent advances in understanding the structural hierarchy of trichocyte keratins, including their heterodimeric structure and distinct conformations impacting hair growth, with no new experimental results reported.
13 citations
,
April 1997 in “Biochemical and Biophysical Research Communications” This study observed that insulin-dependent diabetes induces specific molecular changes in the keratin structure of hair, potentially offering a new way to study diabetic complications through easily accessible tissues.
9 citations
,
August 2012 in “Thermochimica Acta” In this study, researchers found that finasteride exhibits a solid-solid phase relationship that is enantiotropic at normal pressure and becomes monotropic at higher pressure.
8 citations
,
April 2017 in “Journal of The Royal Society Interface” This study found that keratin intermediate filaments in the hair of GAN patients are altered, showing decreased diffraction signals and increased stiffness, strength, and extensibility.
7 citations
,
January 1973 in “Calcified Tissue International” This study found that hair follicle tissue effectively induced mineral formation in calcium phosphate solutions, likely due to its nucleating ability, which was lost when the tissue was lyophilized and stored.
6 citations
,
January 2012 in “Breast cancer” This study suggests that breast cancer-associated phospholipids may alter the X-ray diffraction pattern of hair, potentially enabling the development of a sensitive and specific screening test for breast cancer.