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Aging reduces skin cell renewal and defense against germs due to TGFbeta, but blocking TGFbeta could help restore these functions.

Foxp3+ Regulatory T Cells are important for immunity and tolerance, affect hair growth and wound healing, and their dysfunction can contribute to obesity-related diseases and other health issues.

Epidermal stem cells create and maintain skin structures like hair and nails through specific signaling pathways and vary by location and function.

HtrA2 activity is crucial for normal hair growth by regulating fat cell development.

We need to learn more about 5α-reductases and neuroactive steroids to safely make drugs targeting these enzymes.

Autophagy helps keep skin healthy and may improve treatments for skin diseases.

Damaging mutations in NFKB2 cause a severe and distinct form of primary immunodeficiency with early-onset and often ACTH-deficiency.

Sex hormones may influence COVID-19 severity, with males at higher risk, and certain hormone therapies could potentially treat the virus.

4-Aminopyridine improves skin wound healing and tissue regeneration by increasing cell growth and promoting nerve repair.

Blocking certain pathways with kinase inhibitors may help treat cutaneous lupus erythematosus.

Antigen presenting cells around hair follicles are crucial in SLE-related hair loss.

Catalytic antibodies are early indicators and active participants in the development of systemic lupus erythematosus.

Abusing steroids can damage your heart, muscles, reproductive system, liver, skin, and brain, and may increase the risk of Alzheimer's disease.

Older skin has higher cancer risk due to inflammation and stem cell issues.

Acne is linked to inflammation and insulin resistance, and is associated with various syndromes that require different treatments.

ATP-dependent chromatin remodeling is crucial for skin development and stem cell function.

The protein Par3 is crucial for healthy skin, affecting the skin barrier, cell differentiation, and stem cell maintenance.

Sonic hedgehog proteins may help grow hair.

Lenalidomide helps hair follicle stem cells turn into melanocytes, which may improve repigmentation in vitiligo.

Cathepsin L is essential for normal hair growth and development.

Aging causes skin stem cells to work less effectively.

Different PIN proteins affect plant root hair growth by changing how auxin is transported.

Overexpressing Dsg3 in mice skin causes excessive cell growth and abnormal skin development.

C60 fullerenes can alter protein function and may help develop new disease inhibitors.

Scientists turned mouse stem cells into skin cells that can grow into skin layers and structures.

The document concludes that certain genetic mutations and dietary factors are involved in acne development, and treatments like isotretinoin and diet changes can help manage it.

Oxidative stress affects hair loss in men with androgenetic alopecia.

TCDD speeds up skin barrier formation by increasing certain gene expressions.

Pitx2 helps outer root sheath cells differentiate but can't start hair growth on its own.

Skin cell clumping for hair growth is improved by a protein called fibronectin, which helps cells stick and move better.