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This study identified the transcription factor Elf5 as a novel regulator of keratinocyte proliferation and differentiation in skin, with expression elevated in stem/progenitor cell populations, suggesting its potential role in determining cell fate during skin and hair development.

This study found that conditional deletion of Mof in mice resulted in severe defects in skin development, including compromised epidermal differentiation and hair growth, leading to perinatal lethality.

This study reports that despite rescuing neurulation and skin barrier defects, Grhl3 gene overexpression in mice leads to hearing impairment, hair loss, and other developmental abnormalities, highlighting low tolerance for Grhl3 dysregulation.

This study found that Satura Rosta Balm exerts a cytotoxic effect under oxidative stress and may trigger regeneration through autophagic pathways, despite not promoting proliferation or stress resistance in human cells.

In this animal study, the researchers found that DPP4 plays a crucial role in scar formation and wound-induced hair follicle neogenesis in mice, impacting regenerative repair.

This study found that specific human hair keratins are differentially expressed in the hair follicle, suggesting a shared pathway of epithelial differentiation between hair cortex and nail plate cells.

This review discusses the pharmacology and toxicology of cyclooxygenase in skin, highlighting its role in inflammation, wound healing, and tumorigenesis, without presenting new clinical results.

This study found that manipulating Wnt signaling pathways in cutaneous wounds can induce skin structures resembling regeneration, suggesting a potential role for Wnt signals in restoring skin architecture during wound healing.

This review examines the impact of vitamin D signaling in extraskeletal tissues and notes that expected benefits from animal and cell studies have not been consistently replicated in human clinical trials.

This study found that cystatin M/E strongly inhibits human cathepsin V and cathepsin L via distinct non-overlapping sites, suggesting an important role in human epidermal differentiation and hair follicle morphogenesis.

This study discovered that a network controlled by the gene p63 is crucial for keratinocyte differentiation and is linked to MYC through cell adhesion-related pathways.

This study found that prostaglandin metabolism enzymes are present in human hair follicles, suggesting a potential role in hair growth and differentiation, with some expression differences between men and women.

This study found that low-dose UVB radiation enhances the survival, migration, and hair growth-promoting capacity of adipose-derived stem cells in mice through the generation of reactive oxygen species.

This study reports that GLP-1 receptors and proglucagon are expressed in the skin of newborn mice, with GLP-1 potentially playing a role in skin development and hair follicle formation.

This study demonstrated that an engineered human skin equivalent can generate follicle-like structures resembling fetal skin, highlighting the role of the dermal compartment in directing epithelial cell fate in vitro.

This study found that ΔNp63α directly regulates VDR expression, which in turn may reduce invasiveness in an epidermoid cancer cell line.

This study found that the orphan protein Plet-1 is expressed in specific keratinocytes of mouse hair follicles and may regulate keratinocyte interactions with inert tissues by affecting migration and adhesion.

This study found that combining ablative fractional CO₂ laser therapy with hair growth factors significantly increased hair density in men with androgenetic alopecia compared to using growth factors alone.

This review discusses the identification and roles of different epidermal stem cell types in skin homeostasis and repair, and reports no new experimental findings.

This study suggests that TIP39 and its receptor PTH2R, identified in human epidermis, may play a role in keratinocyte function and influence skin differentiation.

This study provided the first proteome dataset for alopecia areata, revealing novel pathways in the disease mechanisms that may lead to new therapeutic targets.

ZPK helps skin cells mature and may affect skin health.

This study highlights the role of Orai1 in ameloblast differentiation and maturation, showing that its down-regulation affects cell proliferation and enamel formation during tooth development.

This study found that Pannexin 3 plays a crucial role in skin development by regulating the transcription factor Epiprofin, affecting keratinocyte differentiation and hair follicle regeneration in mice.

This study suggests that StemMACS MSC Expansion Media is more suitable than PowerStem MSC1 media for expanding therapeutic adipose-derived mesenchymal stem cells, with less expression of negative markers and better chromosomal stability.

This study reports that a plant extract from Orobanche rapum can stimulate skin rejuvenation and protect cutaneous microbiota, potentially creating healthier skin.

This study found that hair follicle mesenchymal stem cells are similar to bone marrow stem cells in most characteristics, but differ in their adipogenic and osteogenic differentiation capabilities, suggesting they may be a suitable source for adipogenesis research.

This study developed a composite hydrogel that delivered multiple proteins, enhancing skin wound healing by accelerating closure and promoting hair follicle regeneration.

This study found that the FGF-2 mimetic SUN11602 and VEGF mimetic ONO-1301 had unique effects on skin fibroblasts and keratinocytes, indicating potential for improving wound healing.

This study concluded that the inner root sheath inhibits the expression of certain differentiation markers in hair bulbs, with calcium-induced changes paralleling those seen in hair follicle mid-segments.