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This study found that mechanical stress activates a WISP-1/Hedgehog signaling axis that contributes to ligamentum flavum hypertrophy and fibrosis, identifying Hedgehog signaling as a potential therapeutic target.

This review examines how fibroblasts contribute to regeneration in various organs and explores the potential of reverting adult fibroblasts to a fetal-like state for regenerative therapies, but reports no new empirical findings.

In this study using a mouse model and human hair follicle cells, shikimic acid was found to promote hair growth and may serve as a new therapeutic agent for alopecia.

This study found that BMP6 and Wnt10b competitively regulate the transition between hair follicle growth phases, offering new insights into hair follicle cycling and potential hair loss treatments.

This study found that dual 5α-reductase inhibition in rats led to decreased sperm motility and altered morphology, resulting in subfertility.

This review discusses the role of stem cells in alopecia pathogenesis, highlighting the differences between scarring and nonscarring types, and reports no new clinical results.

This review discusses the emerging roles of transit-amplifying cells in tissue regeneration and cancer formation, highlighting their significance beyond a mere transitional state in hair follicles and the hematopoietic system.

This study found that combining minoxidil and retinol additively promoted hair growth in vitro, enhancing Erk- and Akt-dependent pathways and preventing apoptosis in dermal papilla cells and keratinocytes.

This study found that intraovarian PRP treatment in women with low ovarian reserve was associated with significant increases in serum AMH levels in some patients, typically within four weeks.

This review discusses the negative health impacts of testosterone deficiency and the potential adverse effects of 5α-reductase inhibitors, emphasizing the need for patient-physician discussions regarding these treatments.

This report describes two patients with frontal fibrosing alopecia who developed acute hair loss on their limbs, revealing that the limb alopecia had similar histological features to scalp alopecia.

In this study, 13-cis-5S*,8S*-epidioxy-5,8-dihydroretinoic acid was found to be significantly more cytotoxic to cancer cell lines than other retinoic acid analogs evaluated.

This article reviews the role of polyamines in hair follicle growth and discusses potential therapeutic applications but provides no new clinical results.

This study found that vitamin D deficiency in patients with alopecia areata was associated with greater disease severity and longer duration, but not with disease pattern or vitamin D receptor expression.

This article reviews existing and emerging treatments for psoriasis, focusing on therapy modifications due to scientific advancements, but it does not report new clinical results.

In this study, the researchers found that vitamin D and calcium signaling in keratinocytes are essential for normal skin regeneration after wounding, with deficiencies significantly delaying wound closure and re-epithelialization in mice.

In this study, researchers found that a polyphenolic extract from Annurca apples, high in procyanidin B2, increased hair growth, density, and keratin content in healthy subjects after 2 months of use, and stimulated keratin biosynthesis in vitro.

In this study, oral administration of Crataegus pinnatifida extract was associated with hair growth promotion in mice by inducing anagen phase and enhancing cell signaling related to hair follicle development.

This study found that keratin coatings from human hair may improve the colony-forming efficiency of human mesenchymal stem cells by moderating donor variability, suggesting a potential use in clinical applications.

This article discusses the interest in folic acid antagonists for leukemia treatment, noting their potential mechanism of interfering with cellular growth, but reports no new clinical results.

This review discusses the latest understanding of androgenetic alopecia, including stem cell niches in hair follicles, and highlights emerging treatments like growth factors and platelet-rich plasma without new clinical findings.

This study found that ILK deficiency disrupts hair follicle development by impairing cell polarity and laminin-511 assembly, but these defects can be partially reversed with exogenous laminin-511.

This study found that adding Wnt-10b to the culture medium of dermal papilla cells maintained their ability to induce hair follicles over 100 days in vitro.

This study utilized magnetic resonance imaging to noninvasively visualize and differentiate skin structures in rat skin, finding a significant correlation between MRI data and histological areas.

This study suggests that miRNAs, particularly miR-195-5p, may regulate the loss of hair follicle inductivity in cultured dermal papilla cells by suppressing the Wnt/β-catenin pathway.

The study created a test that found hormonal and toxic effects in plant and fungal extracts using prostate cancer cells.

This chapter reviews various antiandrogens and androgen inhibitors, detailing their mechanisms, uses, and side effects, with a focus on spironolactone, finasteride, dutasteride, and oral contraceptives.

This study found that various petroleum distillates caused significant skin changes in mice, with severity varying based on the product and penetration pathway, potentially leading to skin tumors through non-genotoxic mechanisms in longer-term exposure.

This review discusses the adverse skin effects of EGFR inhibitors used in cancer treatment, exploring their mechanisms and offering strategies for prevention and management, but reports no new experimental findings.

This review discusses recent findings on molecular changes in cutaneous adnexal tumours and reports novel markers and pathways involved, highlighting the diverse oncogenic drivers and tumour suppressor alterations.