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Skin stem cells interacting with their environment is crucial for maintaining and regenerating skin and hair, and understanding this can help develop new treatments for skin and hair disorders.

Cornification is how skin cells die to form the protective outer layer of skin, hair, and nails.

Wounded skin cells can revert to stem cells and help heal.

Trichohyalin-like proteins are essential for the development of skin structures like hair, nails, and feathers.

Genetic changes in mice help understand skin and hair disorders, aiding treatment development for acne and hair loss.

MMP-9 is essential for proper hair canal formation.

Foxn1 gene regulation is crucial for thymus development but not for hair growth.

Losing both ERBB2 and ERBB3 receptors in mice causes significant skin problems and inflammation.

Hair growth and development are controlled by specific signaling pathways.

Epidermal Wnt/β-catenin signaling controls fat cell formation and hair growth.

The project created a standardized system for classifying skin lesions in lab rats and mice.

Desmoglein 4 is controlled by specific proteins that affect hair growth.

The conclusion is that understanding how hair follicle stem cells live or die is important for maintaining healthy tissue and repairing injuries, and could help treat hair loss, but there are still challenges to overcome.

Notch signaling disruptions can cause various skin diseases.

PPAR-γ is important for healthy hair and its problems, and more research on PPAR-γ treatments is needed.

Rats can't grow new hair follicles after skin wounds, unlike mice, due to differences in gene expression and response to WNT signaling.

Low-dose radiation affects hair stem cell function and survival by changing their genetic material's structure.

Laminin 332 is essential for normal skin cell behavior and structure.

Current methods can't fully recreate skin and its features, and more research is needed for clinical use.

Matriptase is highly active in hair follicles and sebaceous glands, especially during hair growth phases.

Cannabinoids like CBD and THC may help treat non-cancer skin diseases, but more research is needed.

HSPGs help control stem cell behavior, affecting hair growth and offering a target for hair loss treatments.

Understanding keratinization is crucial for treating skin conditions like ichthyoses and psoriasis.

The new microwell device helps grow more hair stem cells that can regenerate hair.

Blocking DPP4 can potentially speed up hair growth and regeneration, especially after injury or in cases of hair loss.

The conclusion is that the nuclear lamina and LINC complex in skin cells respond to mechanical signals, affecting gene expression and cell differentiation, which is important for skin health and can impact skin diseases.

Mice can grow new hair follicles after skin wounds through a process not involving existing hair stem cells, but requiring more research to understand fully.

Trichoblastomas in rabbits are linked to uncontrolled embryonic hair growth and have distinct histological features.

Claudin expression changes help the skin respond to injury.

The skin has multiple layers and cells, serves as a protective barrier, helps regulate temperature, enables sensation, affects appearance, and is involved in vitamin D synthesis.