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Hair graying may help prevent cancer by protecting stem cells.

This review highlights the significant advancements in regenerative medicine from stem cells, PRP, and exosomes for dermatology, but notes that regulatory challenges and the need for standardization are slowing their clinical application.

This case report illustrates that fibrosing alopecia in a pattern distribution may be misdiagnosed as androgenetic alopecia due to similar hair loss patterns, but distinctive trichoscopic and histopathologic features help differentiate it.

In this study, the researchers reported that Krox20 plays a crucial role in epidermal homeostasis and hair development, influencing stem cell maintenance and cell survival through the modulation of cellular pathways.

This study found that hair-follicle-associated-pluripotent (HAP) stem cells can be cryopreserved for future use in nerve and spinal cord repair, with human trials being planned.

This study developed a new quantitative method to measure skin cell turnover in just 4 days, showing it can effectively differentiate skincare product performance and revealing that turnover slows with age but responds more to treatments as people get older.

This case report describes a 59-year-old woman with a rare trichoepithelioma on her eyelid, emphasizing the importance for optometrists to differentiate it from basal cell carcinoma.

This review outlines recent advances in stem cell and tissue engineering technologies in regenerative medicine and wildlife conservation, reporting no new clinical results.

This review discusses the plasticity of epithelial stem cells in regenerative contexts and reports no new research findings; the authors highlight potential implications for regenerative medicine and cancer.

The K15 promoter effectively targets stem cells in the hair follicle bulge.

Human hair follicles can provide stem cells for regenerative medicine.

This study found that squamous cell carcinomas from hair follicle stem cells are more prone to epithelial to mesenchymal transition and metastasis than those from interfollicular epidermis, due to distinct chromatin landscapes.

This article describes protocols for isolating and expanding human epidermal neural crest stem cells and discusses their potential for cell-based therapies in regenerative medicine, but reports no new clinical results.

This study found that nestin-expressing cells in the hair follicle bulge exhibit multipotent stem cell-like properties and can generate neural cells both in vitro and in vivo.

Hedgehog signaling helps keep hair follicle stem cells the same in both young and old human skin.

This study found that human hair follicle-derived mesenchymal stem cells maintained their proliferation and differentiation potential when cultured with acidic fibroblast growth factor, basic fibroblast growth factor, or epidermal growth factor.

This study found that human hair follicle stem cells formed more colonies and adhered more rapidly, while transit-amplifying cells showed significantly greater mobility.

This study found that human adipose-derived stem cells co-cultured on a collagen sponge scaffold showed increased differentiation into keratinocytes, suggesting potential for improved skin wound healing.

This review discusses the emerging roles of transit-amplifying cells in tissue regeneration and cancer formation, highlighting their significance beyond a mere transitional state in hair follicles and the hematopoietic system.

This research discusses a novel imaging approach in live mice to study stem cell and niche interactions in tissue homeostasis and reports no new results.

Skin cells can help create early hair-like structures in lab cultures.

This study reveals that epidermal stem cell differentiation in mice involves dynamic transcriptional changes, with Keratin-10 transcription preceding gradual chromatin compaction shifts associated with differentiation.

This study concluded that hair-derived stem cells from older donors may offer a promising alternative for autologous corneal endothelial replacement, potentially benefitting patients of various age groups.

This review discusses environmental reprogramming and the plasticity of epithelial cells, emphasizing their potential for new cell therapy approaches; it reports no new experimental results.

In this study, the antibody A3 identified quiescent post-progenitor epithelial and mesenchymal cells in developing rat hair follicles, suggesting it may help track the differentiation of these cells.

This study developed a stable cell line model to evaluate hair differentiation activity, offering a new tool for screening drugs that promote hair growth using mouse iPS cell-derived systems.

This review discusses the characteristics and potential applications of epidermal stem cells in dermatology, without providing new clinical results.

This study presents two new mouse models using the CreER T2-loxP system to target and study melanocytic cells, with implications for melanoma research.

This review summarizes the potential therapeutic applications of stem cells in dermatology, emphasizing their role in restorative and regenerative treatments through injections, topical applications, and scaffolds, supported by advancements in laboratory processes and quality control.

This study discovered that the gene Tfap2b identifies a melanocyte stem cell population in zebrafish, essential for regenerating melanocytes with multi-fate potential into adult pigment cells.