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Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Hair and skin can regenerate without bulge stem cells due to other compensating cells.

Exosomes from umbilical cord cells fix hearing loss and damaged ear hair cells in mice.

New treatments and diagnostic methods for various animal skin conditions showed promising results.

SDF-1/CXCL12 and its receptor CXCR4 are crucial for melanocyte movement in mouse hair follicles.

Hair follicles could be used to noninvasively monitor our body's internal clock and help identify risks for related diseases.

Increasing EGR1 levels makes hair root cells grow faster.

Human scalp hair follicles can produce hormones and have a system similar to a brain-body communication network.

Disrupted stem cell signals in hairpoor mice cause hair loss.

New findings suggest certain genes and microRNAs are crucial for wound healing, and innovative technologies like smart bandages and apps show promise in improving treatment.

Finasteride in male rats causes liver and metabolic issues in their offspring.

Epidermal stem cells help heal severe skin wounds and have potential for medical treatments.

Overexpressing a specific enzyme in mice causes hair loss and female infertility.

Deleting MED1 in skin cells causes hair loss and skin changes.

Breast cancer treatments work better with AR activation, improving results and reducing side effects.

Mice without certain skin enzymes have faster hair growth and bigger eye glands.

Bmpr2 and Acvr2a receptors are crucial for hair retention and color.

The HPV type 11 region activates hair-specific gene expression in mice.

Adenosine receptors could be promising targets for treating inflammatory skin diseases like psoriasis.

Dutasteride may help protect neurons and reduce inflammation in Parkinson's disease.

Androgen suppression therapy (AST) doesn't significantly lower bladder cancer risk, but using finasteride, a type of AST, might reduce it. AST decreases recurrence-free survival but doesn't affect overall survival or progression-free survival. More research is needed to understand AST's benefits.

Mongolian gerbils heal wounds differently than mice, with unique protein levels and gene expression that affect skin repair.

Hard skin features like scales, feathers, and hair evolved through specific protein changes in different animal groups.

The three estrogen receptor genes are highly expressed in zebrafish neuromasts during development.

Retinoic acid-binding proteins in skin are regulated by β-catenin and Notch signalling.

Vimentin and transthyretin proteins are linked to black coat color in sheep.

Blocking DHT production more strongly may help control advanced prostate cancer and improve quality of life.

Mice lacking steroid 5α-reductase 2 show less aggression and better impulse control.

5α-reductase inhibitors can cause serious and possibly lasting sexual and psychological side effects.

Certain types of T cells are essential for healthy skin and play a role in skin diseases, but more research is needed to improve treatments.