1 citations,
July 2022 in “Clinical, Cosmetic and Investigational Dermatology” Taohong Siwu Decoction may help treat hair loss by targeting multiple genes and pathways.
1 citations,
May 2022 in “Frontiers in Pharmacology” Astilbin can potentially calm overactive immune responses, like in Type 1 Diabetes, by suppressing certain cell activities and reducing inflammation.
1 citations,
February 2020 in “Cureus” Women with PCOS are more likely to have skin problems like excessive hair, acne, and hair loss.
October 2024 in “Journal of Plant Growth Regulation” Fusarium sp. strain K-23 helps Arabidopsis plants grow better in salty soil by promoting root hair growth.
August 2024 in “Applied Sciences” Plant extracts may help prevent or reverse hair graying.
May 2024 in “Journal of cosmetic dermatology” Low HDL-C, uric acid, and 25-hydroxyvitamin D are risk factors for early-onset male hair loss.
February 2024 in “ACS Omega” The Shen Bai Hair Growing Decoction may help treat hair loss by promoting hair growth and reducing inflammation.
February 2024 in “International Journal of Molecular Sciences” Hair loss in Androgenetic Alopecia is caused by genetics, aging, and lifestyle, leading to hair follicle shrinkage and related health risks.
February 2023 in “Molecules” Cactus extract from Notocactus ottonis may help promote hair growth.
38 citations,
June 2018 in “Archives of Toxicology” Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.
131 citations,
September 2017 in “Molecular and Cellular Endocrinology” The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.
13 citations,
July 2018 in “General and comparative endocrinology” Thyroid hormones and androgens affect gene expression in frog reproductive organs differently between males and females.
18 citations,
March 2020 in “Frontiers in Neuroendocrinology” The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.
February 2024 in “Brain research bulletin” Blocking androgen activity in newborn rats affects body weight and appetite-related hormones differently in males and females.
January 2023 in “Discovery immunology” T cells and bacteria in the gut and skin help maintain health and protect against disease.
8 citations,
March 2020 in “Metabolites” Finasteride treatment changes urine metabolomics and steroid signatures, potentially monitoring effectiveness but may cause sexual side effects.
3 citations,
March 2021 in “Metabolites” Hair loss causes differ between men and women due to changes in hormone levels and inflammation-related pathways.
82 citations,
September 2018 in “Nature Communications” A certain smell receptor in hair follicles can affect hair growth when activated by a synthetic sandalwood scent.
48 citations,
February 2013 in “Molecular and Cellular Endocrinology” The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.
23 citations,
August 2018 in “Biochimica and biophysica acta. Molecular and cell biology of lipids” Different sPLA2 enzymes affect immunity, skin and hair health, reproduction, and may be potential targets for therapy.
196 citations,
May 2001 in “The journal of investigative dermatology/Journal of investigative dermatology” Sebocytes play a key role in controlling androgen levels in human skin.
46 citations,
September 2011 in “Journal of Endocrinology” Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.
22 citations,
November 2011 in “Journal of Analytical Toxicology” Scientists have developed a new method to detect steroid abuse in athletes using cell-based tests, which could be the future of anti-doping methods.
20 citations,
December 2011 in “Journal of inherited metabolic disease” Valproic acid treatment increases a specific acid in urine by blocking an enzyme, possibly causing skin rash and hair loss.
11 citations,
July 2015 in “Gene” DHT affects bone growth by altering gene activity in osteoblasts, potentially complicating steroid use.
The document concludes that the development of certain tumors is influenced by genetic background and that a specific gene modification can lead to tumor regression and reduced growth.
50 citations,
January 2014 in “PLOS ONE” Heavy ion radiation has a more severe and long-lasting effect on mouse intestinal metabolites than gamma radiation.
29 citations,
November 2022 in “Nature Medicine” Genetic variations greatly affect individual metabolism and can impact health and disease risk.
1 citations,
January 2023 in “Metabolites” Changes in gut bacteria can contribute to the development of Polycystic Ovary Syndrome (PCOS), affecting metabolism, immunity, and causing inflammation. Treatments may involve adjusting these factors.
August 2022 in “Metabolites” Different types of skin on mice have unique chemical profiles related to how they grow and react to stress.