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A special gene region controls the re-emergence of a primitive wool type in Merino sheep, improving their wool yield and adaptability.

Collagen-enhanced mesenchymal stem cells significantly improve skin wound healing.

Androgens can both increase body hair and cause scalp hair loss.

UV radiation can help sterilize wounds and promote healing but requires careful use to avoid damaging cells.

Keratin protein production in cells is controlled by a complex system that changes with cell type, health, and conditions like injury or cancer.

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

Two drugs, finasteride and minoxidil, are approved for hair loss treatment, but new therapies are being developed.

Polycystic Ovary Syndrome (PCOS) is a hormonal disorder in women that can cause infertility and other health issues, and it may be improved by treatments that increase insulin sensitivity.

Methotrexate treats various disorders by inhibiting DNA synthesis, but careful monitoring is needed to avoid toxicity and manage side effects.

Cancer development is like natural selection, involving mutated cells and environmental factors.

Cancer rates are increasing in developed countries, with estrogen, aging, low vitamin D3, and HPV infection as common causes.

Vitamin D receptor can control the hairless gene linked to hair loss even without vitamin D.

Activating Nrf2 in skin cells causes skin disease similar to chloracne in mice.

Methotrexate is a key, cost-effective drug for skin conditions, but requires careful monitoring for side effects.

New treatments for hair loss from alopecia areata may include targeting immune cells, using stem cells, balancing gut bacteria, applying fatty acids, and using JAK inhibitors.

Hair disorders are caused by a complex mix of biology, genetics, hormones, and environmental factors, affecting hair growth and leading to conditions like alopecia.

Enzymes are classified into six types and are essential for many biological processes, with only a few targeted by drugs.

Ginsenoside Re from ginseng may help hair grow by blocking a specific growth-inhibiting pathway.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Wnt7a protein is crucial for development and tissue maintenance and plays varying roles in diseases and potential treatments.

Human skin can make serotonin and melatonin.

DNA can predict physical traits like eye and hair color accurately, especially in Europeans, but predicting other traits and in diverse populations needs more research.

DNA methylation is essential for skin and hair follicle development, and could be a target for treating skin diseases.

Mice lacking a key DNA methylation enzyme in skin cells have a lower chance of activating stem cells necessary for hair growth, leading to progressive hair loss.

Histone demethylases play a key role in the development of many diseases and may be targets for treatment.

TGFβ's manipulation of inflammation and immune cells affects cancer spread, suggesting new treatment strategies and biomarkers.

Finasteride can cause lasting sexual dysfunction, depression, and other side effects, needing more research for treatment.

A specific RNA modification in cashmere goats helps activate hair growth-related stem cells.

Stem cell therapies show promise for treating various diseases but face challenges in clinical use and require better monitoring techniques.