January 2026 in “Clinical Dermatology Review” This study found that platelet-rich plasma therapy significantly improved hair density, diameter, and reduced inflammation in androgenetic alopecia patients compared to placebo, though individual responses varied.
September 2025 in “International Journal of Innovative Technologies in Social Science” This study found that low-dose oral minoxidil (≤5 mg/day) effectively increased hair number and diameter in men and women with androgenetic alopecia, and was generally well-tolerated with mostly mild adverse effects, although serious complications were rare and associated mainly with pre-existing heart conditions.
July 2025 in “Journal of Ayurveda and Holistic medicine.” In this study, researchers reported significant improvements in hair follicle diameter, thickness, and reduced hair root gap after treating male pattern hair loss with a regimen of Prachanna, Chitrakadi lepa, and Jeevamrutham lehyam over four months.
April 2025 in “Ukrainian Journal of Veterinary and Agricultural Sciences” This study observed that feeding ewes a water-soluble complex of fatty acids increased primary hair follicle bulb diameter and mitotic activity, suggesting a positive correlation with wool growth.
February 2025 in “Archives of Dermatological Research” This study found that combining microneedling with 5% Minoxidil and Finasteride significantly improved hair density and hair shaft diameter in males with androgenetic alopecia, outperforming Minoxidil alone or in combination with Finasteride, although changes in hormonal levels and trace elements were not significant.
January 2024 in “Photodiagnosis and Photodynamic Therapy” The study found that combining a 655nm low-level laser helmet with 2% minoxidil resulted in better improvement in hair diameter and intermediate hair enlargement at the midscalp among Chinese women with FPHL.
December 2023 in “Clinical, cosmetic and investigational dermatology” This study found that specific dermoscopic signs, such as diameter diversity of leukotrichia and Pohl-Pinkus constrictions, were associated with progressive vitiligo, and early-stage melanin synthesis was impaired in vitiligo-associated leukotrichia.
January 2019 in “Journal of Entomology and Zoology Studies” This study observed that in Assam Hill Goats, the primary hair follicles had larger diameters and more structural associations compared to secondary follicles, especially in ruminant-age groups.
February 2013 in “Journal of the American Academy of Dermatology” In this study, the HairCheck device was reported to accurately assess changes in hair density and diameter, suggesting its usefulness in monitoring alopecia progression and treatment response.
November 2008 in “Medical & surgical dermatology” This study reports that a prototype device may accurately measure changes in hair quantity, diameter, and density in patients with balding by assessing the cross-sectional area of hair bundles.
January 2020 in “프로그램북(구 초록집)” This study found that treating androgenetic alopecia patients with microneedle-delivered GFC containing FGF5s and NMN increased hair density and diameter compared to normal saline.
April 2018 in “Journal of Investigative Dermatology” This study found that 1550-nm Er:Glass fractional laser treatment significantly increased hair density and shaft diameter in patients with androgenetic alopecia, though the mechanism may not involve Wnt10A or IGF-1 expression.
January 2018 in “International Journal of Medical Reviews and Case Reports” This study found that a 12-week topical application of bimatoprost 0.03% significantly increased the diameter of vellus hairs in patients with androgenic alopecia.
94 citations
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January 2000 in “The Journal of Clinical Endocrinology and Metabolism” This study found that spironolactone, flutamide, and finasteride are similarly effective in reducing hair diameter and Ferriman-Gallwey scores in women with hirsutism over a 6-month treatment period.
78 citations
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October 2012 in “Biomaterials” This study found that both human and rat dermal papilla spheroids can induce hair follicle neogenesis, but larger spheroids increase inductivity without significantly affecting hair fiber diameter.
78 citations
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May 1989 in “The Journal of Clinical Endocrinology & Metabolism” This study found that in hirsute women, daily treatment with 200 mg spironolactone significantly reduced hair growth rates and hair shaft diameters on various body areas over 12 months.
67 citations
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February 2009 in “Journal of Dermatology” This study found that dermoscopy can be a useful tool for diagnosing androgenetic alopecia, particularly in determining hair diameter diversity as an essential feature in Asian populations.
45 citations
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December 2018 in “Lasers in Medical Science” In a 24-week randomized trial, this study found that the RAMACAP laser helmet significantly increased hair density and diameter in androgenetic alopecia patients compared to a sham device, although limitations included a small sample size and potential issues with the control used.
32 citations
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July 1999 in “Fertility and Sterility” This study found that both finasteride and flutamide effectively reduced hirsutism, with flutamide being more effective than finasteride in decreasing hirsutism scores and hair diameter over 12 months.
24 citations
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September 2002 in “Dermatologic Surgery” This study suggests that transplanting hair to new nonscalp sites affects their growth and survival rates, though the hair diameter remains consistent.
23 citations
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April 1999 in “The Journal of Clinical Endocrinology and Metabolism” This study found that flutamide, finasteride, ketoconazole, and EE-CPA all significantly reduced hirsutism scores, hair diameter, and hair growth rate in women with hirsutism over 12 months.
19 citations
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May 2016 in “Clinical, cosmetic and investigational dermatology” In this study, applying FGF-2-containing dalteparin/protamine nanoparticles to the scalp was associated with a significant increase in hair diameter over six months among participants with thin hair.
17 citations
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September 2020 in “Inflammation and Regeneration” In this study, researchers found that WNT activation influenced FGF expression in human scalp-derived fibroblasts, with mouse model results showing FGF9 increased hair follicle number and diameter, while FGF7 reduced diameter.
17 citations
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June 1990 in “PubMed” This study examined the morphological variations of terminal hair from different body regions of a Caucasian male, finding notable differences in diameter and features like "steak-boning" in specific hair types.
15 citations
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March 2018 in “Journal of The American Academy of Dermatology” This study found that platelet-rich plasma combined with other hair restoration therapies significantly increased hair density in patients with androgenetic alopecia, though it did not statistically affect hair shaft diameter.
15 citations
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January 2012 in “International journal of trichology” This study found that the HairCheck® device, demonstrating high correlation between its Hair Mass Index and hair characteristics such as strand number and diameter, may be an effective tool for assessing hair mass changes in alopecia patients.
12 citations
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August 2011 in “Asian-Australasian Journal of Animal Sciences” This study found that polymorphisms in the KAP8.1 gene were significantly associated with cashmere weight, length, and guard hair length in Chinese Inner Mongolian Cashmere goats, but not with fibre diameter.
9 citations
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June 2024 in “Genes” This study examined the Spanish Merino breed's wool quality, identifying 74 genetic variants linked to key wool traits like fiber diameter and staple length, which could help restore the breed's potential for producing high-quality wool.
9 citations
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February 2023 in “Genes” This study reveals that long non-coding RNAs influence cashmere fiber traits in goats by interacting with target genes involved in pathways affecting fiber diameter and color.
8 citations
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February 2016 in “The American Journal of Dermatopathology” In this study, the researchers found that transplanted hair follicles undergo significant morphological changes, including a thickened dermal sheath and increased hair shaft diameter, which are associated with altered follicular vascularization.