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Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Hair proteins have weak spots in their α-helical segments.

The testosterone patch and gel are both effective, but they have different absorption patterns and effects on hormone levels.

The document suggests that clinical trials for PCOS should focus on meaningful primary outcomes like live birth rates, rather than less reliable surrogate markers.

Toxic shock syndrome is caused by a complex interaction of bacterial toxins and the immune system, and understanding this can help improve diagnosis and treatment.

Minoxidil effectively controls blood pressure but side effects may limit its use.

The conclusion is that formalizing how past decisions influence current health technology assessments could improve the credibility and defense of coverage decisions.

Minoxidil can cause dangerous fluid buildup around the heart.

Minoxidil-loaded liposomes effectively deliver to hair follicles, potentially improving hair growth and treating alopecia.

Systemic Lupus Erythematosus has varied symptoms and is hard to diagnose, affecting many body parts and requiring careful clinical judgment.

Minoxidil and caffeine in transfersomes improve hair growth treatment.

Chitosan-coated nanoparticles improve skin delivery of hair loss treatments with fewer side effects.

Nanostructured lipid carriers improve minoxidil delivery for hair loss treatment.

Testosterone therapy may slightly improve sexual function in postmenopausal women, but its long-term safety is unknown.

Nanoencapsulation creates adjustable cell clusters for hair growth.

Taking 5-α reductase inhibitors for prostate enlargement or hair loss does not significantly raise the risk of erectile dysfunction.

ΔNp63α stops TAp73β from working in skin cancer by blocking its access to specific genes, not by directly interacting with it.

Teriflunomide is effective and generally safe for treating relapsing-remitting multiple sclerosis.

Enzyme purified and characterized for minoxidil sulphation in rat liver.

A new hair loss treatment uses tiny needles to deliver a drug-loaded lipid carrier, promoting hair growth more effectively than current treatments.

New lipid nanoparticles show promise for delivering hair loss treatments but need improvement for better skin penetration.

Oleic acid nanovesicles improve minoxidil absorption in hair follicles for alopecia treatment.

The document concludes that using LC-MS/MS for measuring androgens is more accurate than older methods, but it needs careful validation and standardized references to be most effective.

Diagnosing PCOS in teenagers should focus on signs of excess male hormones and not rely solely on ovarian ultrasound or irregular periods, and should be reassessed in adulthood.

L-Carnitine-L-tartrate may help hair grow and prevent hair loss.

Finasteride improves hair growth.

Calcium is important for stem cell function and maintenance, especially in blood and skin cells.

Acitretin is effective for severe psoriasis and can be used long-term due to no immunosuppression, but must be carefully monitored for side effects and is not for pregnant women.

Minoxidil in HA-PLGA nanoparticles effectively treats alopecia through skin delivery.

Some growth factors, while important for normal body functions, can cause diseases when not regulated properly.