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    Glossary Diabetic Ulcers

    open sores on feet due to diabetes-related complications

    Diabetic ulcers, also known as diabetic foot ulcers, are open sores or wounds that occur in individuals with diabetes, typically on the feet. These ulcers result from a combination of factors such as poor blood circulation, neuropathy (nerve damage), and a weakened immune system, which impair the body's ability to heal. If left untreated, diabetic ulcers can lead to serious complications, including infections and, in severe cases, amputation.

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    Research 30 of 1000+

    1. Thou shall not heal: Overcoming the non-healing behaviour of diabetic foot ulcers by engineering the inflammatory microenvironment Advanced Drug Delivery Reviews · 2023 · 90 citations
    2. Skin microbiota and diabetic foot ulcers Frontiers in Microbiology · 2025 · 6 citations
    3. Comparative Assessment of Topical Platelet-Rich Plasma and Phenytoin for Diabetic Foot Ulcer Healing in a Rat Model University of Science and Technology Journal for Medical Sciences · 2026
    4. 1492 Prostacyclin pathway to enhance wound healing in diabetic foot ulcers Journal of Investigative Dermatology · 2023
    5. Exosome-based cell therapy for diabetic foot ulcers: Present and prospect Heliyon · 2024 · 9 citations
    6. Risk factors for diabetic foot ulcers mortality and novel negative pressure combined with platelet-rich plasma therapy in the treatment of diabetic foot ulcers Frontiers in Pharmacology · 2022 · 14 citations
    7. Innovative microneedle-integrated hydrogels: a promising strategy for diabetic foot ulcer management Frontiers in Bioengineering and Biotechnology · 2026
    8. Efficacy of Activated Autologous Platelet-Rich Plasma in The Treatment of Diabetic Foot Ulcers: An Evidence-Based Brief Literature Review Biotechnological Research · 2022
    9. Fibroblasts in Diabetic Foot Ulcers International Journal of Molecular Sciences · 2024 · 33 citations
    10. Platelet Rich Plasma Effects on Diabetic Foot Ulcers - A Review National Journal of Health Sciences · 2023 · 3 citations
    11. Fat grafting and platelet‐rich plasma for the treatment of diabetic foot ulcers: A feasibility‐randomised controlled trial International Wound Journal · 2020 · 55 citations
    12. Use of Leukocyte Platelet (L-PRF) Rich Fibrin in Diabetic Foot Ulcer with Osteomyelitis (Three Clinical Cases Report) Diseases · 2018 · 38 citations
    13. Innovative Functional Biomaterials as Therapeutic Wound Dressings for Chronic Diabetic Foot Ulcers International Journal of Molecular Sciences · 2023 · 12 citations
    14. Exploring the Role of GLP‐1 Agents in Managing Diabetic Foot Ulcers: A Narrative and Systematic Review Wound Repair and Regeneration · 2025
    15. Platelet-rich plasma-loaded bioactive chitosan@sodium alginate@gelatin shell-core fibrous hydrogels with enhanced sustained release of growth factors for diabetic foot ulcer healing International Journal of Biological Macromolecules · 2023
    16. Study on the regulatory effect of Panax notoginseng saponins combined with bone mesenchymal stem cell transplantation on IRAK1/TRAF6-NF-κB pathway in patients with diabetic cutaneous ulcers Journal of Orthopaedic Surgery and Research · 2023 · 10 citations
    17. Dual-functional hybrid quaternized chitosan/Mg/alginate dressing with antibacterial and angiogenic potential for diabetic wound healing Journal of Orthopaedic Translation · 2021 · 43 citations
    18. Interleukin-25-Mediated-IL-17RB Upregulation Promotes Cutaneous Wound Healing in Diabetic Mice by Improving Endothelial Cell Functions Frontiers in Immunology · 2022 · 34 citations
    19. Inhibiting the cytosolic function of CXXC5 accelerates diabetic wound healing by enhancing angiogenesis and skin repair Experimental & Molecular Medicine · 2023 · 19 citations
    20. Major Improvement in Wound Healing Through Pharmacologic Mobilization of Stem Cells in Severely Diabetic Rats Diabetes · 2020 · 16 citations
    21. Enhancing diabetic wound healing: advances in electrospun scaffolds from pathogenesis to therapeutic applications Frontiers in bioengineering and biotechnology · 2024 · 5 citations
    22. Risk factors of peripheral occlusive arterial disease in patients with diabetic retinopathy due to type 2 diabetes Srpski arhiv za celokupno lekarstvo · 2024
    23. An off-the-shelf bioactive EV delivering cryogel orchestrating immunomodulatory reprogramming and angiogenesis for diabetic ulcer healing Biomaterials · 2026
    24. Pharmacological Activity and Clinical Use of PDRN Frontiers in Pharmacology · 2017 · 80 citations
    25. Systematic Review: Adipose-Derived Mesenchymal Stem Cells, Platelet-Rich Plasma and Biomaterials as New Regenerative Strategies in Chronic Skin Wounds and Soft Tissue Defects International Journal of Molecular Sciences · 2021 · 70 citations
    26. Skin diseases in consequence of endocrine alterations The Aging Male · 2006 · 16 citations
    27. Evidence-based consensus on the clinical application of photobiomodulation Journal of the American Academy of Dermatology · 2025 · 16 citations
    28. Cathelicidins: Opportunities and Challenges in Skin Therapeutics and Clinical Translation Antibiotics · 2024 · 7 citations
    29. Trace element zinc and skin disorders Frontiers in Medicine · 2023 · 4 citations
    30. Local anti-inflammatory effect and immunomodulatory activity of chitosan-based dressing in skin wound healing: a systematic review Journal of clinical and translational research · 2022 · 4 citations