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The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.

People with PCOS, especially if obese, often have NAFLD, linked to obesity, insulin resistance, and high androgen levels.

Oral retinoids are effective for various skin conditions but have side effects and should not be used during pregnancy.

UV radiation can help sterilize wounds and promote healing but requires careful use to avoid damaging cells.

New hormonal contraceptives are safer, have fewer side effects, and offer health benefits for women.

Vitiligo is linked to autoimmune diseases and hearing issues, so hearing tests are recommended for patients.

Hidradenitis suppurativa is caused by genetic factors, inflammation, bacteria, hormones, and lifestyle factors like obesity and smoking.

Blocking the enzyme 11β-HSD1 might help treat obesity and metabolic issues.

Mood stabilizers like lithium and anticonvulsants have side effects that can lead to patients stopping their medication, and managing these effects is important for treatment adherence.

The document suggests that clinical trials for PCOS should focus on meaningful primary outcomes like live birth rates, rather than less reliable surrogate markers.

Alopecia is linked to various health and mental conditions, impacts life quality, and needs medical attention beyond its cosmetic effects.

The document concludes that new treatments are needed to better manage acne and reduce side effects related to current therapies.

Testosterone therapy seems safe and effective for transgender men with proper care, but more long-term research is needed.

Every elderly patient had at least one skin condition, often linked to other diseases, highlighting the need for integrated skin and general healthcare in the elderly.

Acitretin is effective for severe psoriasis and can be used long-term due to no immunosuppression, but must be carefully monitored for side effects and is not for pregnant women.

Delayed ejaculation is a complex issue caused by psychological, biological, and lifestyle factors, requiring a holistic treatment approach.

Chronic kidney disease can cause skin problems that affect patient quality of life, and treating these conditions can improve outcomes.

The Chinese version of the PCOS quality of life questionnaire is reliable and valid for Chinese-speaking women with PCOS.

Vitiligo patients should be routinely screened for thyroid disease and, if extensive or prolonged, also for RA, PA, and type 2 diabetes.

Testosterone helps human pancreatic cells increase insulin release.

The conclusion is that there is a high demand for new contraceptives that provide both pregnancy prevention and protection against STIs, along with additional health benefits.

A woman was the first known case to have both polycystic ovary syndrome and autoimmune polyglandular syndrome type 2, suggesting a need to check for both conditions in similar patients.

Skin health and diseases are closely linked to metabolic processes.

Hormone therapy may increase migraines in transgender women and decrease them in transgender men; more research is needed on migraine management in transgender individuals.

A patient with Werner syndrome showed a range of aging-like symptoms and metabolic issues, underscoring the need for early detection and treatment.

Hormonal therapies are safe and effective for treating acne in female adolescents, with specific treatments for those with endocrine disorders.

Hair loss is linked to insulin resistance in women, regardless of hormone levels.

Metformin and thiazolidinediones are similarly effective for PCOS, but metformin is often preferred due to fewer side effects.