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A topical treatment safely and effectively reduced acne by causing targeted cell death in sebaceous glands without side effects.

Finasteride, a drug that changes testosterone to a different hormone, was studied and its effects over time were modeled successfully.

Dihydrotestosterone treatment on 2D and 3D-cultured skin cells slows down hair growth by affecting certain genes and could be a potential target for hair loss treatment.

Dutasteride and finasteride can help increase hair growth gene expression but need further improvement.

Finasteride and dutasteride are effective in treating male hair loss but can cause sexual side effects and birth defects.

5 Alpha-Reductase Inhibitors reduce the effects of testosterone by blocking its conversion into a stronger form.

5-alpha reductase inhibitors may have additional effects on cancer, mental health, heart health, and hormone levels beyond treating prostate enlargement.

Finasteride effectively treats hair loss and prostate issues with minimal side effects.

Finasteride slowly binds to 5-alpha-reductase, affecting enzyme stability and inhibitor potency.

Finasteride treats enlarged prostate and baldness, but may cause limited urinary improvement and sex-related side effects.

Substances from fat-derived stem cells can promote hair growth and counteract hormone-related hair loss by activating a key hair growth pathway.

LY191704 is a compound that effectively blocks a specific enzyme involved in hormone conversion and could help treat enlarged prostate and hair loss.

A reliable model for screening type II 5α-reductase inhibitors was created and validated.

ADSC-Exos with miR-122-5p can help treat hair loss by promoting hair growth.

Some plant-based products might treat hair loss with fewer side effects than current medications.

Compound 4 is a promising treatment for hair loss with low toxicity.

Finasteride may treat baldness but less effective for those with 5α-reductase deficiency.

Male androgenetic alopecia involves hair follicle miniaturization due to DHT, with potential treatments using inhibitors and blockers.

Finasteride effectively blocks enzyme causing male pattern baldness.

5 alpha reductase inhibitors can cause sexual, cognitive, and muscle side effects, and may slightly increase aggressive cancer risk.

Rosa rugosa extract promotes hair growth and could be a natural treatment for hair loss.

Blocking the enzyme that turns testosterone into DHT can safely and effectively treat enlarged prostate.

Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.

Blocking a specific enzyme in male rat fetuses leads to the development of nipples and feminized genitalia.

Understanding how DHT works is important for diagnosing and treating hormone-related disorders.

Long-term use of a certain medication can worsen erectile function in aged rats by damaging penile muscle cells.

Androgenetic alopecia is a common hair loss condition caused by testosterone effects on hair follicles, leading to thinner, shorter, and less pigmented hair, diagnosed using scalp dermoscopy and treated with topical minoxidil, antiandrogen agents, and 5-alpha reductase inhibitors.

Researchers developed a model to predict how well certain compounds can block an enzyme related to hair loss and prostate issues, suggesting a 50 mg dose of finasteride might be effective based on lab and body data.

Finasteride doesn't affect oral testosterone undecanoate, and high DHT levels may cause acne, prostate issues, and hair loss.

Finasteride lowers DHT levels and raises testosterone in a dose-dependent way.