research Prostate Cancer and Androgenic Alopecia
The document suggests more research is needed to understand the link between baldness and prostate cancer.
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research The Relation Between Androgenetic Thin Hair Diagnosed by Trichoscope and Benign Prostatic Hyperplasia
Men with thinner hair from genetic hair loss may be more likely to have an enlarged prostate.
research Use of Finasteride in the Treatment of Men With Androgenetic Alopecia
Finasteride effectively improves hair growth and slows hair loss in men with male pattern baldness.
research Inhibition of Rat 5α-Reductase Activity and Testosterone-Induced Sebum Synthesis in Hamster Sebocytes by an Extract of Quercus Acutissima Cortex
An extract from Quercus acutissima bark was found to reduce sebum production and block an enzyme linked to acne.
research Key Targets of Hormonal Treatment of Prostate Cancer: The Androgen Receptor and 5α-Reductase
Blocking DHT production more strongly may help control advanced prostate cancer and improve quality of life.
research Metformin Influence on Hormone Levels at Birth in PCOS Mothers and Their Newborns
Metformin taken during pregnancy increases SHBG in newborns but doesn't change other hormone levels in mothers or babies.
research Activation of Androgen Receptor Sensitizes Breast Carcinomas to NVP-BEZ235's Therapeutic Effect Mediated by PTEN and KLLN Upregulation
Breast cancer treatments work better with AR activation, improving results and reducing side effects.
research A Mechanism for Topical Cutaneous Calcinosis
Epilation and DHT cause skin calcification by increasing ATP and calcium deposits.
research Effects of Taxifolin-3-O-Arabinopyranoside from Rhododendron Mucronulatum Root Extracts on the Alleviation of Hair-Loss Symptoms
The compound from Rhododendron mucronulatum roots may help treat male pattern hair loss.
research The Antiandrogenic Effect of Finasteride Against a Mutant Androgen Receptor
Finasteride may improve prostate cancer treatment outcomes.
research Androgenetic Alopecia in Women and Men: Italian Guidelines Adapted from European Dermatology Forum/European Academy of Dermatology and Venereology Guidelines
Italian guidelines recommend using trichoscopy for diagnosis and treatments like minoxidil for hair loss.
research A Review on Steroidal 5α-Reductase Inhibitors for Treatment of Benign Prostatic Hyperplasia
New treatments for enlarged prostate are being developed, some of which may be more effective than current medications.
research Platelet-Rich Plasma Therapy in the Treatment of Androgenic Alopecia – Review
Platelet-rich plasma therapy shows promise in treating hair loss caused by androgenic alopecia.
research The Organ-Maintained Human Sebaceous Gland
Human sebaceous glands can grow normally for a week without certain growth factors, and adding estrogen reduces their oil production without affecting cell growth.
research Trace Elements Content and Hormonal Profiles in Women with Androgenetic Alopecia
Women with AGA have more androstenedione and dihydrotestosterone, less copper and zinc; copper imbalance affects AGA; treatment improves hormones and minerals.
research Intermolecular NH2-/Carboxyl-Terminal Interactions in Androgen Receptor Dimerization Revealed by Mutations That Cause Androgen Insensitivity
Mutations at Val-889 and Arg-752 disrupt key interactions in the androgen receptor, affecting its function.
research Steady-State Pharmacokinetics of Oral Testosterone Undecanoate with Concomitant Inhibition of 5α-Reductase by Finasteride
Finasteride doesn't affect oral testosterone undecanoate, and high DHT levels may cause acne, prostate issues, and hair loss.
research Management of Neonates and Children with Male Pseudohermaphroditism
Individuals with male pseudohermaphroditism often do better raised as females with early surgery.
research Mechanisms of Testosterone Action
Testosterone works in different ways, including direct interaction with its receptor, conversion to other hormones for specific effects on genitalia, hair, bones, and muscle, and changes in body fat and sexual function when low.
research Dihydrotestosterone Induces p27 Degradation via Direct Binding with SKP2 in Ovarian and Breast Cancer
Dihydrotestosterone causes p27 protein breakdown in ovarian and breast cancer cells by binding with SKP2.
research Androgenic Alopecia: A Counterproductive Outcome of the Anabolic Effect of Androgens
Male pattern baldness is an unintended side effect of the body's use of androgens for muscle growth, especially in those genetically prone to it.
research Pharmacokinetics of a Transdermal Testosterone Cream in Healthy Postmenopausal Women
A 5 mg dose of transdermal testosterone cream effectively restores testosterone levels in postmenopausal women.
research URB Expression in Human Dermal Papilla Cells
The gene URB is more active in human hair growth cells and responds to a hair-related hormone.
research Steroid 5α-Reductase 2 Deficiency Leads to Reduced Dominance-Related and Impulse-Control Behaviors
Mice lacking steroid 5α-reductase 2 show less aggression and better impulse control.
research Activation of Hair Cell Growth Factors by Linoleic Acid in Malva Verticillata Seed
Linoleic acid from Malva verticillata seeds may help treat hair loss by promoting hair cell growth and blocking baldness signals.
research Sebocytes’ Makeup: Novel Mechanisms and Concepts in the Physiology of the Human Sebaceous Glands
Hormones and signaling pathways control sebaceous gland function and could help treat acne.
research Clinical Observation of Yifa Compound Treating 40 Cases of Female Pattern Hair Loss and Its Effect on Serum Dihydrotestosterone and Dehydroepiandrosterone
Yifa compound effectively treats female pattern hair loss and lowers DHT and DHEA levels.
research In Vivo and In Vitro Exposure to Free Fatty Acids Induce Increased Androgen Production in Animal Models: A Potential Pathogenic Factor of Polycystic Ovary Syndrome
Free fatty acids may increase androgen production, potentially contributing to polycystic ovary syndrome.
research Finasteride in the Treatment of Androgenetic Alopecia
Finasteride effectively treats male pattern baldness, improving hair growth and density.
research Biological Activity of Novel Progesterone Derivatives Having Bulky Ester Side Chains at C-3
The more lipophilic the progesterone derivative, the better it binds to androgen receptors and has antiandrogenic effects.