research Combination of an Antiandrogen and a 5α-Reductase Inhibitor: A Further Step Towards Total Androgen Blockade?
Using two drugs together, Flutamide and 4-MA, is more effective for blocking male hormones than using each one alone.
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research Influence of Dosing Time on the Efficacy and Safety of Finasteride in Rats
Dosing time affects finasteride's effectiveness and safety in rats.
research Selective Induction of Apoptosis in the Hamster Flank Sebaceous Gland Organ by a Topical Liposome 5-Alpha-Reductase Inhibitor: A Treatment Strategy for Acne
A topical treatment safely and effectively reduced acne by causing targeted cell death in sebaceous glands without side effects.
research Pharmacokinetics of Modified Slow-Release Oral Testosterone Over 9 Days in Normal Men With Experimental Hypogonadism
The new oral testosterone pill normalized testosterone levels and lowered SHBG in men with low testosterone.
research The Role of Androgens in Hormone Replacement Therapy
Androgen therapy can help with symptoms like low libido in women, but more research is needed to understand its long-term safety and effects on health.
research Serum Dihydrotestosterone Levels Are Associated With Adverse Myocardial Remodeling in Patients With Severe Aortic Valve Stenosis Before and After Aortic Valve Replacement
Higher DHT levels are linked to worse heart changes in severe aortic valve stenosis patients.
research Is Dihydrotestosterone a Classic Hormone?
Dihydrotestosterone (DHT) mainly affects nearby cells, doesn't significantly change prostate hormonal environment or cancer risk, and doesn't play a main role in causing hair loss or acne. More research is needed on its effects on heart health, sexual function, and bone health.
research The Effect of Leonuri Herba Alkaloids on Senile BPH (Male and Female Hormone Induced) Model Rats
Leonuri Herba alkaloids may help treat hormone-induced enlarged prostate in rats.
research Dutasteride: A Review of Its Use in the Management of Prostate Disorders
Dutasteride is effective for treating prostate enlargement and reducing related surgery risk, but is not approved for preventing prostate cancer.
research Application of Ostrich Antibodies to the Restoration of Hair Growth, a Preliminary and Case Report
Ostrich antibodies helped regrow hair in men with hair loss, but the application needs to be easier.
research Behavioral and Hormonal Changes Following the Continuous Administration of Testosterone in Adult Female Capuchin Monkeys (Sapajus Libidinosus)
Testosterone increases sexual behavior in female capuchin monkeys.
research Dual Deficiency of Melatonin and Dihydrotestosterone Promotes Stromal Cell Damage and Mediates Prostatitis via the cGAS-STING Pathway in Sleep-Deprived Mice
Lack of sleep in mice leads to prostatitis by reducing certain hormones and activating an inflammatory pathway, which can be temporarily fixed with normal sleep.
research The Hormonal Background of Hair Loss in Non-Scarring Alopecias
Hormones like androgens, estrogen, thyroid hormones, and stress hormones can contribute to hair loss, and treatments target these hormonal imbalances.
research Platelet-Rich Plasma Therapy in the Treatment of Androgenic Alopecia – Review
Platelet-rich plasma therapy shows promise in treating hair loss caused by androgenic alopecia.
research Oral and Topical Administration of Standardized Saw Palmetto Oil Reduces Hair Fall and Improves Hair Growth in Androgenetic Alopecia Subjects: A 16-Week Randomized, Placebo-Controlled Study
Saw palmetto extract reduced hair loss and improved hair growth in people with hair thinning.
research Screening the Chemical Composition and Bioactivity of Cerasus Serrulata Flower Extracts Using Two Extraction Methods
Cerasus serrulata flower extracts have strong antibacterial and antioxidant effects and may help prevent hair loss.
research Bioinformatic Analysis of Gene Expression Data Reveals Src Family Protein Tyrosine Kinases as Key Players in Androgenetic Alopecia
Protein tyrosine kinases are key in male pattern baldness, affecting skin structure, hair growth, and immune responses.
research Targeting JAK/STAT and Wnt/Beta-Catenin Pathways and 5-Alpha-Reductase Activity to Develop an Effective Anti-Hair Loss Product
The lotion with specific plant extracts effectively increased hair growth and improved hair cycle in subjects after 3 months.
research Intracrine Testosterone Activation in Human Pancreatic Beta Cells Stimulates Insulin Secretion
Testosterone in human pancreas cells boosts insulin production.
research Intracrine Testosterone Activation in Human Pancreatic Beta Cells Stimulates Insulin Secretion
Testosterone in our bodies helps increase insulin secretion from the pancreas.
research Male Pattern Baldness: Symptoms, Causes, and Treatments
Male pattern baldness is a common hair loss in men caused by genetics and hormones, with treatments including drugs, hair transplants, and hair loss products.
research Synergistic Therapeutic Effect of Ginsenoside Rg3 Modified Minoxidil Transfersomes on Androgenic Alopecia in C57BL/6 Mice
Ginsenoside Rg3 combined with minoxidil was more effective in treating hair loss in mice.
research Testosterone Modulates Vasodilation in Mesenteric Arteries of Hypertensive Rats
Testosterone affects blood vessel relaxation in hypertensive rats.
research Active Pharmaceutical Ingredient-Ionic Liquids Assisted Follicular Co-Delivery of Ferulic Acid and Finasteride for Enhancing Targeted Anti-Alopecia
The new delivery system improves treatment for hair loss by enhancing drug absorption and effectiveness.
research The Microbiome in Hair Disorders
Changes in skin bacteria can affect hair loss and new treatments targeting these bacteria may prevent balding without sexual side effects.
research The Efficacy of Ostrich Antibodies to Dihydrotestosterone and 5α-Reductase in the Restoration of Hair Growth
Ostrich antibodies can help restore hair growth in people with a specific type of hair loss, increasing hair count by 71% on average.
research Medicinal Plants Used in Mexico for the Treatment of Alopecia
Mexican medicinal plants are used to treat hair loss.
research Disorders Linked to Insufficient Androgen Action in Male Children
Male children's genital development issues can be caused by genetic mutations or environmental factors affecting hormone action.
research Untargeted Metabolomics and Steroid Signatures in Urine of Male Pattern Baldness Patients After Finasteride Treatment for a Year
Finasteride treatment changes hormone levels in male pattern baldness patients.
research Scalp Threading – New Treatment Option for Androgenetic Alopecia
Scalp Threading is a promising new treatment for hair loss that may work better than current options.