research Analysis of the MicroRNA Expression Profile of Normal Human Dermal Papilla Cells Treated with 5α-Dihydrotestosterone
DHT affects hair follicle cells by changing microRNA levels, leading to less cell growth and more cell death.
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research Effect of Finasteride on Serum Concentrations of Dihydrotestosterone and Testosterone in Three Clinically Normal Sexually Intact Adult Male Dogs
Finasteride significantly reduces DHT levels in male dogs without affecting testosterone levels, suggesting it could be used to treat benign prostatic hypertrophy in dogs weighing 10 to 50 kilograms.
research Camellia Seed Cake Extract Supports Hair Growth by Abrogating the Effect of Dihydrotestosterone in Cultured Human Dermal Papilla Cells
Camellia seed cake extract may help hair growth by blocking the hair loss effects of a hormone called DHT.
research Testosterone Metabolite Nonessential For Androgen Effects
The body's change of testosterone into DHT is not necessary for testosterone's muscle and sexual effects.
research A Mechanism for Topical Cutaneous Calcinosis
Epilation and DHT cause skin calcification by increasing ATP and calcium deposits.
research Hair Growth Effect of AT-Grow Using Natural Plants
AT-Grow, a natural product, might help with a common type of hair loss by reducing DHT levels.
research Effect of Testosterone Supplementation With and Without a Dual 5α-Reductase Inhibitor on Fat-Free Mass in Men with Suppressed Testosterone Production: A Randomized Controlled Trial
Testosterone increases muscle mass regardless of DHT conversion blocking.
research Androgenic Alopecia: Characteristics and Perspectives
Male pattern baldness is mainly caused by a hormone called dihydrotestosterone (DHT), and drugs that can block this hormone might help prevent hair loss.
research Clinical Observation of Yifa Compound Treating 40 Cases of Female Pattern Hair Loss and Its Effect on Serum Dihydrotestosterone and Dehydroepiandrosterone
Yifa compound effectively treats female pattern hair loss and lowers DHT and DHEA levels.
research Synergistic Effect of Carbodiimide and Dehydrothermal Crosslinking on Acellular Dermal Matrix
Combining DHT and EDC improves the strength and stability of PADM scaffolds for tissue engineering.
research 5α-Reductase Activity in the Prostate
Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.
research The Human Skin as a Hormone Target and an Endocrine Gland
Human skin acts like a hormone-producing organ, making and managing various hormones important for skin and hair health.
research Effects of In Utero Exposure to Finasteride on Androgen-Dependent Reproductive Development in Male Rats
Exposure to finasteride in the womb caused lasting reproductive issues in male rats.
research Role of 5α-Reductase in Health and Disease
5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.
research Anti-Androgenic Activities of Ganoderma Lucidum
Ganoderma lucidum, a type of mushroom, may help treat enlarged prostate by blocking testosterone conversion.
research The Effects of Finasteride on Scalp Skin and Serum Androgen Levels in Men with Androgenetic Alopecia
Finasteride effectively reduces hair loss by decreasing androgen levels.
research Finasteride in the Treatment of Androgenetic Alopecia
Finasteride effectively treats male pattern baldness, improving hair growth and density.
research Treatment of MSCs with Wnt1a-Conditioned Medium Activates DP Cells and Promotes Hair Follicle Regrowth
Wnt1a-conditioned medium from stem cells helps activate cells important for hair growth and can promote hair regrowth.
research Male Pattern Hair Loss: Current Understanding
Genetics and hormones cause hair loss; finasteride treats it safely.
research Steroidogenesis Inhibitors Alter But Do Not Eliminate Androgen Synthesis Mechanisms During Progression to Castration-Resistance in LNCaP Prostate Xenografts
Steroidogenesis inhibitors change but don't stop androgen production in prostate cancer.
research Regulation of Masculinization: Androgen Signaling for External Genitalia Development
Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.
research 5α-Reductase Activity in the Human Hair Follicle Concentrates in the Dermal Papilla
The enzyme that changes testosterone to a stronger form is mostly found in the part of the hair follicle called the dermal papilla.
research Use of Finasteride in the Treatment of Men With Androgenetic Alopecia
Finasteride effectively improves hair growth and slows hair loss in men with male pattern baldness.
research A Bald Statement: Current Approaches to Manipulate Miniaturization Focus Only on Promoting Hair Growth
The conclusion is that future hair loss treatments should target the root causes of hair thinning, not just promote hair growth.
research Hormone-Dependent Medial Preoptic, Lumbar Spinal Cord, and Autonomic Coordination Supporting Male Sexual Behaviors
Testosterone and its byproducts help support male sexual behavior through different pathways in the brain and body.
research Ketoconazole as an Adjunct to Finasteride in the Treatment of Androgenetic Alopecia in Men
Ketoconazole shampoo with finasteride improves hair density in men with hair loss.
research Inhibitory Activities of Some Traditional Chinese Herbs Against Testosterone 5α-Reductase and Effects of Cacumen Platycladi on Hair Regrowth in Testosterone-Treated Mice
Certain Chinese herbs, especially Cacumen platycladi, can promote hair regrowth and reduce hair loss-related hormone levels in mice.
research Serenoa Repens Extracts Promote Hair Regeneration and Repair of Hair Loss in Mouse Models by Activating TGF-β and Mitochondrial Signaling Pathway
Serenoa repens extract helps regrow hair and repair hair loss by activating certain cell growth pathways.
research The Role of Androgen Therapy
Androgens, male hormones, play a role in both men and women's health, and testosterone therapy can help women with low levels, but it's not suitable for pregnant or lactating women, or those with certain conditions.
research A Systematic Review of Topical Finasteride in the Treatment of Androgenetic Alopecia in Men and Women
Topical finasteride reduces hair loss and promotes hair growth in men and women.