research Androgen Profile Through Life in Women With Polycystic Ovary Syndrome: A Nordic Multicenter Collaboration Study
Women with PCOS have higher androgen levels that decrease with age but are still higher than in women without PCOS.
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research Steroidogenesis of the Testis: New Genes and Pathways
New genes and pathways are important for testosterone production and male sexual development.
research The SAHA Syndrome: Overview and Classification
SAHA syndrome is a condition in women involving skin and hair issues, often related to hormonal imbalances, and is treated based on the underlying cause.
research Clinical and Endocrine Effects of Finasteride, a 5α-Reductase Inhibitor, in Women with Idiopathic Hirsutism
Finasteride reduces hairiness and androgen levels in women with unexplained excessive hair growth.
research Expression of mRNA for Androgen Receptor, 5α-Reductase, and 17β-Hydroxysteroid Dehydrogenase in Human Dermal Papilla Cells
Hair sensitivity to androgens is partly controlled by specific enzyme expressions in different hair areas.
research Comparison of Diane 35 and Diane 35 Plus Finasteride in the Treatment of Hirsutism
Diane 35 plus finasteride is more effective for treating hirsutism.
research Changes in the PCOS Phenotype with Age
PCOS symptoms change with age; younger women have higher androgen levels and less metabolic issues, while older women face more metabolic challenges despite milder PCOS symptoms.
research Patients Treated for Male Pattern Hair Loss with Finasteride Show Altered Levels of Neuroactive Steroids in Cerebrospinal Fluid and Plasma After Discontinuation
Finasteride affects brain and blood steroids, causing lasting sexual and emotional side effects.
research Polycystic Ovary Syndrome and Insulin-Resistant Hyperinsulinemia
Insulin resistance contributes to hormone imbalances in many women with polycystic ovary syndrome.
research Relationships Between Cerebrospinal Fluid GABAergic Neurosteroid Levels and Symptom Severity in Men with PTSD
Lower levels of certain brain chemicals are linked to worse PTSD symptoms in men.
research Neuroactive Steroid Levels and Psychiatric and Andrological Features in Post-Finasteride Patients
Post-finasteride patients show changed neuroactive steroid levels, possibly causing erectile dysfunction and depression.
research The Dihydrotestosterone Hypothesis of Prostate Cancer and Its Therapeutic Implications
The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.
research Differential Expression of miR-93 and miR-21 in Granulosa Cells and Follicular Fluid of Polycystic Ovary Syndrome Associating with Different Phenotypes
The study found that certain microRNAs are higher in the cells and lower in the fluid of women with a specific type of polycystic ovary syndrome, and one microRNA could potentially help diagnose the condition.
research Decreased Androgen Receptor Gene Methylation in Premature Pubarche: A Novel Pathogenetic Mechanism?
Reduced AR gene methylation may cause early pubic hair growth in girls.
research Cutaneous Findings and Systemic Associations in Women With Polycystic Ovary Syndrome
Women with PCOS often have more body hair, acne, and skin darkening, and these signs are linked to metabolic issues like insulin resistance and high cholesterol.
research Androgen Profiling by Liquid Chromatography–Tandem Mass Spectrometry in Healthy Normal-Weight Ovulatory and Anovulatory Late Adolescent and Young Women
The research found that anovulatory young women have higher androgen and hormone levels than those who ovulate, suggesting immature hormonal regulation rather than a specific condition.
research Androgens and Hair Loss: An In-Depth Analysis of Androgenetic Alopecia
The document concludes that hair transplantation and gene therapy may be important for future hair loss treatment.
research The Therapeutic Use of Androgens in Women
Testosterone replacement may improve sexual desire and bone health in women with low androgen levels, but more research is needed on its long-term safety.
research Influence of Spironolactone Treatment on Endothelial Function in Non-Obese Women with Polycystic Ovary Syndrome
Spironolactone improved blood vessel function and cholesterol levels in non-obese women with PCOS.
research A Prospective, Randomized Trial Comparing Flutamide (250 mg/d) and Finasteride (5 mg/d) in the Treatment of Hirsutism
Flutamide reduces hair growth better but has more side effects.
research Finasteride in the Treatment of Hirsutism: New Therapeutic Perspectives
Finasteride effectively treats hirsutism in women, but more research needed for long-term results.
research Comparison of Cyproterone Acetate Plus Ethinyl Estradiol and Finasteride in the Treatment of Hirsutism
Cyproterone acetate plus ethinyl estradiol is generally more effective in treating hirsutism, but consider side effects and patient characteristics.
research Association Between the D19S884 Marker at the Insulin Receptor Gene Locus and Polycystic Ovary Syndrome
There's no significant link between the D19S884 marker at the insulin receptor gene and polycystic ovary syndrome.
research Role of Androgens in Female-Pattern Androgenetic Alopecia, Either Alone or Associated with Other Symptoms of Hyperandrogenism
Androgens significantly affect female hair loss, and hormonal treatments may help.
research Localization of Minoxidil Sulfotransferase in Rat Liver and the Outer Root Sheath of Anagen Pelage and Vibrissa Follicles
Minoxidil works in liver and outer hair root sheath for hair growth.
research Finasteride 5 mg/Day Treatment of Patterned Hair Loss in Normo-Androgenetic Postmenopausal Women
Finasteride 5 mg/day effectively treats hair loss in postmenopausal women without hyper-androgenism.
research 17-Hydroxyprogesterone Responses to Gonadotropin-Releasing Hormone Reveal Distinct Phenotypes of Functional Ovarian Hyperandrogenism and Polycystic Ovary Syndrome
The research found that polycystic ovary syndrome (PCOS) has two distinct types, with one having more severe hormone and insulin issues.
research Hirsutism: Evaluation and Treatment
Excessive hair growth can be assessed by history, exam, and blood tests, and treated with medication like dexamethasone, birth control pills, and spironolactone.
research Prevalence of CYP21 Mutations and IRS1 Variant Among Women With Polycystic Ovary Syndrome and Adrenal Androgen Excess
Some women with PCOS have CYP21 mutations and IRS1 variants, but these genetic factors are not major contributors to PCOS.
research Comparison of Clinical and Laboratory Characteristics of Cases with Polycystic Ovarian Syndrome Based on Rotterdam’s Criteria and Women with Only Oligo/Anovulation or Hirsutism
Women with only irregular periods or excess hair have a better hormone profile than those with full PCOS, but both groups are similar, indicating a need for better PCOS diagnosis methods.