25 citations,
December 2017 in “The Journal of Clinical Endocrinology & Metabolism” Birth control pills combined with bicalutamide are more effective at reducing excessive hair growth in women with PCOS than birth control pills alone.
25 citations,
August 2006 in “Human Reproduction” Oral contraceptives lower testosterone levels in women, especially those with certain genetic traits, and may be linked to increased breast cancer risk.
24 citations,
March 2017 in “Archives of Gynecology and Obstetrics” The study found that women with hyperandrogenic PCOS have higher levels of AKT1 and AKT2 proteins in their cells, which may lead to cell dysfunction.
23 citations,
January 1994 in “Skin Pharmacology and Physiology” Hair loss in men and women is linked to high stress hormone levels and other hormonal imbalances, suggesting treatments should be customized to each person's hormones.
22 citations,
June 2004 in “Journal of The European Academy of Dermatology and Venereology” A woman had both Graham Little-Piccardi-Lassueur syndrome, causing hair loss, and complete androgen insensitivity syndrome, making her genetically male but physically female. This suggests androgens don't affect the hair loss condition.
21 citations,
March 2019 in “Critical Reviews in Clinical Laboratory Sciences” The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.
20 citations,
January 2003 in “Treatments in Endocrinology” Testosterone therapy can help improve mood, sexual function, and bone health in women with low androgen levels, but more research is needed to establish safe and effective guidelines.
19 citations,
January 2017 in “Hormone Molecular Biology and Clinical Investigation” High levels of male hormones are very common in women with PCOS and affect their metabolism differently depending on their weight.
19 citations,
July 2013 in “The obstetrician & gynaecologist” The document concludes that careful evaluation is needed to diagnose PCOS correctly due to similar symptoms in other conditions, and accurate testosterone level measurement is crucial.
19 citations,
May 2007 in “Dermatologic therapy” The document concludes that various treatments, including laser therapy, are effective for managing pseudofolliculitis barbae, especially in darker skin types.
18 citations,
March 2008 in “British Journal of Dermatology” Finasteride works better for hair loss in patients 26 or younger.
17 citations,
March 2016 in “Liver international” Men with advanced liver disease and high oestrone and low testosterone levels have worse health outcomes.
17 citations,
February 1989 in “Fertility and sterility” Cimetidine did not reduce hair growth in women with hirsutism.
16 citations,
September 2008 in “Dermatologic Therapy” CAH is a genetic disorder affecting cortisol production and causing hormonal imbalances, with treatment and diagnosis varying by form and symptoms.
16 citations,
January 2008 in “Acta dermato-venereologica” Vitamin B12 deficiency can cause skin darkening and increased blood vessels, but treatment can improve symptoms.
16 citations,
March 2000 in “Clinical Biochemistry” Women with hair loss had higher levels of certain hormones, suggesting a link to a condition like PCOS.
15 citations,
August 2021 in “Reviews in endocrine and metabolic disorders” COVID-19 and hypopituitarism (reduced pituitary gland function) are linked, with the latter's related health issues potentially worsening COVID-19 outcomes, and COVID-19 possibly increasing risk for pituitary complications.
14 citations,
December 2010 in “Seminars in Oncology” Rare adrenal cancers that secrete androgens or estrogens have a poor prognosis and are treated primarily with surgery.
14 citations,
September 1986 in “Archives of Dermatology” Women with low SHBG levels and a high 3a-diol G to SHBG ratio are likely to experience female pattern baldness, possibly due to a slight excess of androgens affecting sensitive hair bulbs.
13 citations,
December 2012 in “Frontiers in bioscience” Vitamin D and estrogen may help protect heart and kidney health, and maintaining sufficient vitamin D levels could be especially beneficial for African Americans, postmenopausal women, and people with chronic kidney disease.
12 citations,
March 2018 in “Medicine” A postmenopausal woman's hirsutism and high testosterone levels improved after surgery for an ovarian tumor not seen on ultrasound.
12 citations,
January 2009 in “Gynecological Endocrinology” A postmenopausal woman's hair loss and excess hair growth improved after surgery for ovarian hyperthecosis.
8 citations,
October 2010 in “Scandinavian Journal of Clinical & Laboratory Investigation” Normal-range ALT levels can indicate metabolic and hormonal imbalances in young women.
7 citations,
September 2014 in “Journal of Obstetrics and Gynaecology Research” Ultrasound measurement of the ovarian stroma to total area ratio is not a reliable single predictor of high male hormone levels in Thai women with PCOS, but works better when combined with clinical signs.
6 citations,
April 2018 in “Obstetrics, gynaecology and reproductive medicine” Most women with hirsutism have it because of PCOS, and they need long-term treatment including medication and hair removal to improve their condition.
6 citations,
December 2016 in “Journal of Dermatology” Dutasteride effectively and safely treats male hair loss for over a year.
5 citations,
June 2021 in “Pharmacological Reports” Vitamin D may help reduce antibody levels in men with autoimmune thyroiditis and early-onset androgenic alopecia, but has no significant impact on thyroid function.
5 citations,
November 2016 in “Experimental and Therapeutic Medicine” BeauTop improves hair growth in androgenetic alopecia patients.
5 citations,
January 2014 in “Postepy Dermatologii I Alergologii” Hormonal treatments like birth control pills can improve acne in women with excess hair growth and hormone imbalances.
5 citations,
October 2013 in “Endocrine” Blood tests can detect ovarian Leydig cell tumors when scans don't, and surgery can confirm and treat these tumors.