171 citations,
July 2007 in “Journal of Investigative Dermatology” A substance called DKK-1 increases in balding areas and causes hair cells to die when exposed to DHT.
82 citations,
August 2006 in “Pharmacology, Biochemistry and Behavior” Certain steroids in the brain affect mood and symptoms of depression, and treatments targeting these steroids show promise for improving these symptoms.
January 2023 in “Iranian Journal of Pharmaceutical Research” Stauntonia hexaphylla extract can help treat hair loss by blocking certain hormones.
May 2023 in “Animal Reproduction Update” High levels of cortisol in hair show long-term stress which can lower fertility in animals.
5 citations,
September 2017 in “PubMed” A new type of amniotic tissue graft improves wound healing better than other grafts.
22 citations,
April 2015 in “Current problems in dermatology” Human hair follicles have a unique metabolism that changes between growth stages and may contribute to baldness.
16 citations,
June 2008 in “Springer eBooks” Over 50% of women over 50 experience hair loss, with minoxidil being the only proven effective treatment.
8 citations,
May 2020 in “Arthritis research & therapy” DHT inhibition may increase spinal bone growth in ankylosing spondylitis.
November 2014 in “Elsevier eBooks” Gene mutations can cause problems in male genital development.
January 2024 in “Aesthetic Plastic Surgery” Botox can help prevent hair loss by blocking cell death in scalp cells.
54 citations,
April 2010 in “Baillière's best practice and research in clinical endocrinology and metabolism/Baillière's best practice & research. Clinical endocrinology & metabolism” Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.
6 citations,
May 2022 in “Research and reports in urology” Caesalpinia bonduc seed extracts may help treat enlarged prostate in rats.
9 citations,
January 2016 in “PubMed” Stem cell therapy could be a promising alternative for hair regrowth with fewer side effects.
1 citations,
June 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” Fetal skin has unique immune cells different from adult skin.
4 citations,
February 2019 in “Breast Cancer Research and Treatment” DHL-HisZnNa may help reduce hair loss from chemotherapy, but more research is needed.
3 citations,
May 2018 in “Journal of nutritional health & food science” Nutritional supplements can help manage hair loss and promote hair growth by strengthening hair roots and countering harmful effects of pollution, smoking, and deficiencies in vitamins and minerals.
11 citations,
August 1997 in “Expert Opinion on Therapeutic Patents” Many potential alopecia treatments need more testing to confirm they promote acceptable hair growth with minimal side effects.
May 2013 in “Journal of the Egyptian Women's Dermatologic Society (Print)” High aldosterone and free testosterone levels link to female hair loss; testing aldosterone may predict hypertension risk.
8 citations,
September 2010 in “Journal of Men's Health” Androgenic Alopecia, a common hair loss condition, can be effectively treated with finasteride and other treatments.
10 citations,
November 2012 in “The journal of investigative dermatology/Journal of investigative dermatology” Korean and Caucasian men with male pattern baldness have different hair steroid levels.
November 2023 in “Scientific reports” The research identified and described a gene important for hormone conversion in endangered catfish, which varies in activity during different reproductive stages and after hormone treatment.
June 2023 in “International journal of research in ayurveda and pharmacy” Dhatryadi Rasayana, an Ayurvedic herbal mix, may be a safe and effective way to prevent premature hair greying.
28 citations,
May 2015 in “Addiction Biology” Prenatal stress changes how male and female rats enjoy rewards differently, linked to sex hormones.
50 citations,
February 2013 in “Annals of Clinical Biochemistry” Understanding how DHT works is important for diagnosing and treating hormone-related disorders.
9 citations,
March 2015 in “Journal of Microbiology and Biotechnology” Ultra-high molecular weight poly-γ-glutamic acid may help promote hair growth.
195 citations,
February 2007 in “The Journal of Clinical Endocrinology and Metabolism” Dutasteride and finasteride may reduce sperm count and volume but don't affect movement or shape; effects are reversible after stopping.
40 citations,
April 2013 in “Dermato-endocrinology” People with chronic Alopecia Areata often have lower vitamin D levels.
75 citations,
February 2016 in “The Journal of Sexual Medicine” Androgens play a role in female sexual function, and testosterone therapy can help women with low sexual desire, but more research is needed on treatments and long-term safety.
9 citations,
January 2014 in “Medical Hypotheses” Higher DHT in male baldness may protect against prostate cancer.
11 citations,
September 2020 in “Journal of Cosmetic Dermatology” Silver nanoparticles can significantly promote hair growth.