Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This review discusses the roles of the hairless (HR) protein as a corepressor, particularly its impact on RORα-mediated transcriptional repression, and reports no new experimental findings.

This study found that boosting the synthesis of neural-derived 17β-estradiol effectively counteracted the impairment of hippocampal long-term potentiation caused by amyloid beta 1-42 in rat hippocampal slices, with the effect seemingly linked to glutamate NMDAR signaling.

This Ph.D. project aims to evaluate the self-assembling potential of hair keratin extracts and study the cellular response to both crude and purified keratins, highlighting their potential applications from biomedical to water remediation.

This study found that secretory proteins in DFCM play crucial roles in regulating nerve restoration by forming significant protein interaction networks during the wound repair process.

This study found that PES1CMU-defatted rice bran (DFRB) showed effective skin whitening and anti-aging properties comparable to standard treatments in cell models, suggesting its potential use in dermatocosmetics.

This study reports that topical fish oil treatment in GsdmA3 Dfl/+ mice increased cellular proliferation and macrophages but did not affect COX-2 expression related to psoriasis-like skin changes.

This randomized, controlled clinical trial found that combining 25 mg/d bicalutamide with 1 mg/d minoxidil for 24 weeks did not enhance hair density improvement in female pattern hair loss compared to 1 mg/d minoxidil alone, with no significant difference observed between the groups.

This retrospective cross-section study found that in a cohort of Pica patients in Iraq, 92.4% were female, and many had low levels of ferritin, hemoglobin, and vitamin D, which may contribute to the disorder by causing psychological issues.

This review explores the applicability of the current PCOS diagnostic criteria, highlighting the need to reassess these criteria in light of new evidence on the disorder's heterogeneity and potential subtypes.

In this review, the authors discuss the promising role of exosomes from various cell sources as potential cell-free therapies for diabetic foot ulcers, highlighting their therapeutic benefits in wound healing and the challenges faced in their clinical application.

This review discusses the potential of activated autologous platelet-rich plasma (aaPRP) for improving diabetic foot ulcer outcomes but reports no new clinical results, noting the need for further evidence.

In this study, the researchers used the dual-flow-RootChip to show that Arabidopsis roots can locally adapt their hair development in response to asymmetric phosphate conditions.

This study found that dermal fibroblast cultures, especially those with higher alpha-smooth muscle actin expression, can be used to produce skin-derived precursor cells, unlike human hair follicle dermal papilla cultures.

This study found that estrogen affected cell behaviors differently in a scratch-wound assay, increasing VEGF secretion in follicular dermal papilla cells but decreasing it in wounded dermal sheath cells.

This study found that while 450nm blue light can inhibit collagen and induce oxidative stress in dermal fibroblasts, 850nm near-infrared light may enhance metabolic activity without causing oxidative damage, suggesting potential for tailored light therapies in skin treatments.

This study used Density Functional Theory to calculate finasteride's molecular properties, finding the GGA/PW91 method aligns well with experimental data and identifying key reactive sites for chemical interactions.

This study introduced the dual-flow-RootChip platform to demonstrate that Arabidopsis roots exhibit non-autonomous adaptations, such as hair growth regulation, when subjected to varied environmental conditions on opposite sides.

This review highlights that unresolved inflammation is a major issue in diabetic foot ulcers and discusses emerging biomaterials-based strategies to modulate the inflammatory response, potentially aiding in tissue regeneration and healing in these chronic wounds.

This study reports that negative pressure wound therapy combined with PRP may effectively accelerate wound healing and reduce mortality in diabetic foot ulcers, with albumin and age identified as independent predictors of mortality risk.

This study highlights the crucial, multifaceted roles of fibroblasts in wound healing and various diseases, including their dysregulation in diabetic foot ulcers, underscoring the need for targeted therapies to address complications and morbidity from such chronic conditions.

In this study, the researchers observed that the transdermal permeation mechanisms of diclofenac salts differ based on counterions, with varying pathways and routes for passive and iontophoretic transport.

This study explored the epigenetic mechanisms of dermal fibroblast progenitor differentiation and found that the repressive chromatin profile from H3K27me3 prevents these progenitors from reforming skin in allograft assays, despite their multipotent potential.

This study observed that in patients with diabetic foot ulcers, an imbalance in skin microbiota, with increased pathogenic bacteria, contributes to infection and poor wound healing, and suggests that modulating microbiota composition might improve healing outcomes.

This review highlights that Microneedle Hydrogels may offer promising advantages for diabetic foot ulcer treatment due to their minimally invasive application and effective drug delivery capabilities.

This review discusses advancements and challenges in using 3D bioprinting for diabetic foot ulcer treatments, highlighting potential improvements and existing limitations in replicating skin architecture and clinical application.

Hair transplantation using micro- and minigraft megasessions is safe, effective, and provides natural results with high patient satisfaction.

This study explored a dual-functional dressing with quaternized chitosan and magnesium, finding it enhanced wound healing and had strong antibacterial effects against drug-resistant bacteria in diabetic rat models with infected foot ulcers, suggesting promise for diabetic foot ulcer treatment.

This study reported that canine dermal papilla cells showed a distinct growth pattern and strong collagen IV and laminin staining compared to dermal fibroblasts.

This study observed that cultured dermal papilla cells showed distinct functional properties from dermal fibroblasts, including lower proliferation rates, higher adhesion to collagen type IV, and different cell-matrix interactions.

This review examines the potential of biomaterial-based wound dressings in managing diabetic foot ulcers, highlighting their versatility and therapeutic properties for promoting wound healing in individuals with diabetes mellitus.