research Anti-DFS70 as a Marker of Non-Systemic Autoimmune Events (Primary Biliary Cholangitis) in Systemic Lupus Erythematosus
Anti-DFS70 antibodies can help identify nonsystemic autoimmune conditions in SLE patients.
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30 / 1000+ resultsresearch Biochemical Features of Primary Cells from a Pediatric Patient with a Gain-of-Function ODC1 Genetic Mutation
A new genetic disorder caused by an ODC1 mutation can be treated with DFMO.
research Alpha-Difluoromethylornithine, a Polyamine Inhibitor: Its Potential Role in Controlling Hair Growth and in Cancer Treatment and Chemoprevention
DFMO may help control hair growth and treat cancer.
research Bachmann–Bupp Syndrome and Treatment
DFMO treatment improves hair growth, muscle tone, and development in Bachmann-Bupp syndrome patients.
research Age-Related Loss of Innate Immune Antimicrobial Function of Dermal Fat Is Mediated by Transforming Growth Factor Beta
Targeting TGFβ can improve skin immunity in older people.
research Co-Operation Between Follicular Ornithine Decarboxylase and v-Ha-ras Induces Spontaneous Papillomas and Malignant Conversion in Transgenic Skin
High levels of ODC and a mutant Ha-ras gene cause tumors in mice.
research A Definitive Role of Ornithine Decarboxylase in Photocarcinogenesis
Inhibiting ODC can prevent UV-induced skin cancer.
research Ornithine Decarboxylase as a Target for Chemoprevention of Basal and Squamous Cell Carcinomas in Ptch1+/– Mice
Inhibiting ornithine decarboxylase may help prevent certain skin cancers.
research Ornithine Decarboxylase as a Target for Chemoprevention of Basal and Squamous Cell Carcinomas in Ptch1+/– Mice
Targeting ornithine decarboxylase can help prevent skin cancer.
research Disturbed Keratinocyte Differentiation in Transgenic Mice and Organotypic Keratinocyte Cultures Due to Spermidine/Spermine N1-Acetyltransferase Overexpression
Overexpression of SSAT causes hair loss and skin issues, but reducing putrescine can help.
research Finasteride-Induced Secondary Infertility Associated with Sperm DNA Damage
Finasteride use may cause sperm damage and infertility, stopping it can improve sperm health.
research Clinical Significance of Dense Fine Speckled Pattern in Anti-nuclear Antibody Test Using Indirect Immunofluorescence Method
The dense fine speckled pattern in ANA tests is common in autoimmune diseases, challenging previous beliefs that it was unrelated.
research Inhibition of Metastatic Squamous Cell Carcinoma Development in Protein Kinase C Epsilon Transgenic Mice by Alpha-Difluoromethylornithine with Hair Follicle Degeneration and Hair Loss
Alpha-difluoromethylornithine prevents cancer in mice but causes hair loss.
research Primary Cicatricial Alopecias
Early diagnosis and aggressive treatment are key for managing rare scalp disorders that cause permanent hair loss.
research Deferasirox, an Oral Iron Chelator, Prevents Hepatocarcinogenesis and Adverse Effects of Sorafenib
Deferasirox combined with sorafenib reduces liver cancer risk and lessens treatment side effects.
research Expanding the Phenotype: Four New Cases and Hope for Treatment in Bachmann-Bupp Syndrome
Four new cases of Bachmann-Bupp syndrome suggest potential for targeted treatment.
research NFIC Promotes the Vitality and Osteogenic Differentiation of Rat Dental Follicle Cells
NFIC helps rat dental cells grow and turn into bone-like cells.
research Development and Evaluation of Polyherbal Formulations for Hair Growth-Promoting Activity
The polyherbal oil with Eclipta alba, Hibiscus rosa sinensis, and Nardostachys jatamansi was found to be highly effective in promoting hair growth, better than minoxidil.
research URB Expression in Human Dermal Papilla Cells
The gene URB is more active in human hair growth cells and responds to a hair-related hormone.
research HIF-1α Stimulators Function Equally to Leading Hair Loss Agents in Enhancing Dermal Papilla Growth
HIF-1α stimulators, like deferiprone, work as well as popular hair loss treatments, minoxidil and caffeine, in promoting hair growth.
research Scaled Quantum Chemical Studies of the Molecular Structure and Vibrational Spectra of Minoxidil
The analysis shows where minoxidil's atoms are likely to react and describes its electronic transitions and behavior with temperature changes.
research Enhancing Diabetic Wound Healing: Advances in Electrospun Scaffolds from Pathogenesis to Therapeutic Applications
Electrospun scaffolds can improve healing in diabetic wounds.
research The Potential Role of Fibroblast-Derived Multi-Peptide Factors in Activation of Growth Factors and Beta-Catenin in Hair Follicle Cells
Multi-peptide factors from fibroblasts may stimulate hair growth by increasing growth factors and β-catenin in hair cells.
research Serendipity in Trichology
Accidental findings have led to new hair treatment discoveries, like using blood pressure and diabetes medications for hair loss and unwanted hair.
research A Correlative Fluorescent and Electron Microscopic Technique for Ultralocalization of Trichocyte Keratins
Researchers developed a new method to clearly see and label hair proteins with minimal errors using advanced freezing and microscopy techniques.
research Investigation of Transcriptional Gene Profiling in Normal Murine Hair Follicular Substructures Using Next-Generation Sequencing to Provide Potential Insights into Skin Disease
Hair follicles have a more inactive cell cycle than other skin cells, which may help develop targeted therapies for skin diseases and cancer.
research Lineage Commitment of Dermal Fibroblast Progenitors Is Mediated by Chromatin De-repression
Skin cell types develop when specific genes are turned on by removing certain chemical tags from DNA.
research GTL1 Is Required for a Robust Root Hair Growth Response to Avoid Nutrient Overloading
GTL1 is needed to control root hair growth and prevent problems when there are too many nutrients.
research Sentinel Lymph Node Status Is the Strongest Independent Predictor for Disease-Free and Overall Survival in Patients with Thick Melanoma
The health of the sentinel lymph node is the best indicator of survival for patients with thick skin cancer.
research Single-Cell RNA Sequencing of Different Fibroblast Populations Cultured from Female Scalp Reveals Significant Alterations to Transcriptional Profiles with Age
Aging changes female scalp cells, likely affecting hair health.