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Cicatricial alopecia, a permanent hair loss condition, is mainly caused by damage to specific hair follicle stem cells and abnormal immune responses, with gene regulator PPAR-y and lipid metabolism disorders playing significant roles.

Epithelial stem cells can adapt and help in tissue repair and regeneration.

Skin stem cells interacting with their environment is crucial for maintaining and regenerating skin and hair, and understanding this can help develop new treatments for skin and hair disorders.

Epidermal stem cells help heal severe skin wounds and have potential for medical treatments.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

Rapamycin reduces age-related hearing cell loss in mice, but acarbose does not.

UV exposure reduces Lgr6+ stem cells in mouse skin and they don't significantly contribute to skin cancer development.

Dihydrotestosterone treatment on 2D and 3D-cultured skin cells slows down hair growth by affecting certain genes and could be a potential target for hair loss treatment.

Skin healing from blisters can delay hair growth as stem cells focus on repairing skin over developing hair.

Proteins like aPKC and PDGF-AA, substances like adenosine and ATP, and adipose-derived stem cells all play important roles in hair growth and health, and could potentially be used to treat hair loss and skin conditions.

Clim proteins are essential for maintaining healthy corneas and hair follicles.

Using low-dose IL-2 to increase regulatory T cells might be a safe way to treat type 1 diabetes without severe side effects.

KDML105 bran extract may help with hair growth and prevent hair loss.

A protein from fat-derived stem cells, DKK1, is linked to hair loss and blocking it may help treat alopecia areata.

Blocking the virus's entry into cells by targeting certain pathways could lead to early COVID-19 treatments.

Cysteine helps maintain keratin production in skin cells even when iron is low.

Minoxidil can stop the growth of ovarian cancer cells without harming the heart.

Melatonin treatment increases a specific RNA in goat cells that boosts cashmere growth.

Keratin is crucial for keeping skin cells healthy and its changes can lead to diseases and affect cell behavior.

Wnt-signaling is regulated differently in skin cells and immune responses during wound healing.

Androgens increase growth factors in skin cells, which may lead to acne.

Changes to the Foxp3 protein affect how well regulatory T cells can control the immune system, which could help treat immune diseases and cancer.

The protein folliculin, involved in a rare disease, works with another protein to control how cells stick together and their organization, and changes in this interaction can lead to disease symptoms.

The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.

Stressed fibroblasts greatly increase melanin production in hair, skin, and eye cells, mainly due to a growth factor called bFGF.

Special particles from skin cells can promote hair growth by activating a specific growth signal.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

LGR5 helps maintain corneal cell characteristics and prevents unwanted changes by controlling specific cell signaling pathways.

Topical drugs and near-infrared light therapy show potential for treating alopecia.

Advanced human skin models improve drug development and could replace animal testing.