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Chrousos Syndrome is caused by mutations that make the body less sensitive to glucocorticoids, leading to various symptoms and requiring high-dose treatment.

imTA and pulse therapy are effective for alopecia areata with manageable side effects, but relapse rates need improvement.

The document suggests creating a validated score to diagnose Cushing's Syndrome and considers plasma steroid profiling as a simpler diagnostic method.

Liposomal anthracyclines are effective and safer for treating multiple myeloma, especially in elderly patients.

Retinoic acid, glucocorticoids, and IGF1 increase IGFBP-3 production in human dermal papilla cells, affecting hair growth.

Some small molecule antivirals show promise against COVID-19, but more research is needed to understand and improve them.

Cronkhite-Canada syndrome may be more treatable and less severe than previously thought.

A sick foal with Rhodococcus equi pneumonia was successfully treated for multiple complications with targeted therapy and careful monitoring.

Proactive monitoring and management are essential to maximize the benefits of Trastuzumab Deruxtecan while minimizing serious side effects.

A woman's severe insulin resistance improved with treatment, but she still had high testosterone levels due to ovarian issues.

The man was diagnosed with stage III multiple myeloma and treated to improve kidney function.

Minoxidil showed a 30% success rate for hair growth in a study, and various skin treatments were effective, but some had limitations or side effects.

Certain defective glucocorticoid receptor mutants move faster inside cell nuclei and work less effectively.

A woman's pelvic pain and bleeding led to finding and successfully treating a rare benign tumor in her reproductive system.

Male hormones like testosterone may make COVID-19 worse, and testing for sensitivity to these hormones could help predict how severe a patient's symptoms might be. Treatments that reduce these hormones are being explored.

A new gene mutation causes female pseudohermaphroditism due to glucocorticoid resistance.

Spironolactone can reduce hair growth in women with hirsutism.

Surface-modified nanoparticles mainly use non-follicular pathways to enhance skin permeation of ibuprofen and could improve treatment for inflammatory skin diseases.

The research found that polycystic ovary syndrome (PCOS) has two distinct types, with one having more severe hormone and insulin issues.

St. John's Wort can cause dangerous high blood pressure if taken with certain foods.

Finasteride reduces hair growth and is safe for women with excessive hair.

Spironolactone is better than placebo for reducing excessive hair growth in women, but its effectiveness for acne is unclear due to small study sizes.

The document concludes that managing non-classical congenital adrenal hyperplasia in females requires personalized treatment, genetic counseling, and a team of specialists.

Cyclodextrins improve how steroid drugs work and are used in marketed medications and environmental applications.

High glucocorticoids cause pancreatic malfunction and malabsorption, reversible with enzyme supplements.

Adrenal gland disease is common in ferrets and causes hair loss and other symptoms.

The cancer drugs bortezomib and lenalidomide cause skin side effects in many patients.

The rapid corticotropin test is a quick and simple way to diagnose adrenal insufficiency.

Oral contraceptives may cause hair loss in women.